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Filtered Search Results
Medchemexpress LLC 21-Hydroxypregnenolone | 1164-98-3 | 98.1% | 332.48 | 1 ML
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21-Hydroxypregnenolone is an essential intermediate in corticosterone synthesis. It is classified as an endogenous metabolite and is related to metabolic diseases and steroids. This product is intended for research and analytical applications.
- Essential intermediate in corticosterone synthesis
- Classified as an endogenous metabolite
- Related to metabolic diseases and steroids
- Suitable for research and analytical applications
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Medchemexpress LLC Resminostat (hydrochloride) | 1187075-34-8 | 99.67% | 385.87 | 25 MG
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Resminostat hydrochloride is a potent inhibitor of HDAC1, HDAC3, and HDAC6, with IC50 values in the nanomolar range. It is used for research applications and appears as a white to off-white solid. This compound shows less potent activity against HDAC8.
- Potent inhibitor of HDAC1, HDAC3, and HDAC6
- Exhibits less potent activity against HDAC8
- Induces histone acetylation in myeloma cells
- Inhibits cell growth and induces apoptosis in myeloma cells
- Synergistic activity with anti-myeloma agents
- Reduces viability of HCC cells when co-treated with AZD-2014
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000703515 GLYCOPYRRONIUM IMPUR 100G
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Medchemexpress LLC GR 64349 | 137593-52-3 | MFCD00153800 | 99.9% | 921.11 | 1 MG
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GR 64349 is a potent and highly selective NK2 receptor peptide agonist with an EC50 of 3.7 nM in rat colon. This compound demonstrates selectivity of over 1000-fold with respect to NK1 receptors and over 300-fold with respect to NK3 receptors.
- Potent and highly selective NK2 receptor peptide agonist.
- Exhibits high selectivity for NK2 receptors over NK1 and NK3 receptors.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000586339 OXIDOPAMINE HYDROCH 500MG
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Ambeed AMBEED
5000866730 2-BROMO-8-PHENYL-124TRIAZO 1GR
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431080 L-PORRETINE 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431192 ISOVANILLIN 25G
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Apexbio Technology LLC Sodium Tauroursodeoxycholate (TUDC) 35807-85-3 10mM (in 1mL DMSO)
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Sodium tauroursodeoxycholate (TUDC CAS 35807-85-3) is a taurine-conjugated bile salt studied for its modulating effects on cholestasis In human erythrocytes TUDC inhibits bile salt-induced efflux of the fluorochrome BCPCF via MRP1 exhibiting an IC50 of 560 M In vitro TUDC partially reverses 17 -estradiol glucuronide (17 EG)-induced reduction of cholyllysylfluorescein canalicular accumulation suggesting an influence on bile secretion dynamics In rat models of phalloidin-induced cholestasis TUDC administration decreases biochemical markers of liver injury and improves biliary excretion of cholesterol and phospholipids These properties make TUDC relevant for research on hepatoprotection and cholestatic mechanisms
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eMolecules 128-08-5 | N-Bromosuccinimide | Oakwood Chemical | MFCD00005510 | 177.985 | C4H4BrNO2 | 99.000 | BrN1C(=O)CCC1=O | 500g | 537663783
N-Bromosuccinimide | Oakwood Chemical | 128-08-5 | MFCD00005510 | 177.985 | C4H4BrNO2 | 99.000 | BrN1C(=O)CCC1=O | 500g | 537663783
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Apexbio Technology LLC Ibandronate sodium 138926-19-9 10mM (in 1mL H2O)
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Ibandronate sodium (CAS 138926-19-9) is a nitrogen-containing bisphosphonate that selectively inhibits farnesyl pyrophosphate synthase within the mevalonate pathway thereby disrupting osteoclast-mediated bone resorption By impairing osteoclast function and survival ibandronate sodium effectively reduces bone turnover This compound is widely utilized in biomedical research to investigate mechanisms related to bone metabolism remodeling and diseases characterized by excessive bone resorption such as osteoporosis Its precise inhibitory profile makes it a valuable tool for studies on osteoclast biology and bisphosphonate pharmacodynamics
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Medchemexpress LLC Trandolaprilate hydrate | 951393-55-8 | 97.3% | C22H32N2O6 | 1 MG
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Trandolaprilate hydrate is a potent angiotensin-converting enzyme (ACE) inhibitor that partially inhibits angiotensin-I-mediated c-fos induction. It is the main bioactive metabolite of Trandolapril and exhibits high lipophilicity. For storage, the product should be kept at -20°C, sealed, away from moisture. If stored in solvent, it is stable at -80°C for 6 months or -20°C for 1 month (sealed storage, away from moisture).
- Potent angiotensin-converting enzyme (ACE) inhibitor.
- Partially inhibits angiotensin-I-mediated c-fos induction.
- Bioactive metabolite.
- High lipophilicity.
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Pfaltz & Bauer 2 4 6-Trichlorophenol 98% - C 500G | 88-06-2
2 4 6-Trichlorophenol 98% - C 500G | 88-06-2
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eMolecules 433926-46-6 | ChemScene | 3-Chloro-5-(trifluoromethoxy)benzoic acid | 1g | 569144911 | CS-0084815 | MFCD06660306 | 240.56 | C8H4ClF3O3
Medchem Express | Danegaptide Hydrochloride | 5mg | 446259523 | HY-10913A | 943133-81-1 | MFCD23160032 | 327.770 | C14H18ClN3O4
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Apexbio Technology LLC RVX-208 1044870-39-4 20mg
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RVX-208 (CAS 1044870-39-4) is a small-molecule inhibitor targeting BET (bromodomain and extra-terminal) proteins It is designed to selectively inhibit the binding of BET bromodomains to acetylated lysine residues thereby modulating transcriptional regulation RVX-208 exerts its biological activity primarily through competitive inhibition of the second bromodomain (BD2) of BET proteins In in vitro studies using human hepatic (HepG2) cells RVX-208 demonstrates BD2 inhibitory activity with an IC50 value of 0 51 M and lower affinity for BD1 (IC50 87 M) Based on these pharmacological properties RVX-208 holds research potential in lipid metabolism cholesterol efflux and atherosclerotic disease processes
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