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Filtered Search Results
Medchemexpress LLC Ceftezole sodium | 41136-22-5 | 1 ML
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Ceftezole sodium is a broad-spectrum cephem antibiotic that is effective against many species of gram-positive and gram-negative bacteria. It also acts as an alpha-glucosidase inhibitor with in vivo anti-diabetic activity.
- Broad-spectrum cephem antibiotic
- Effective against many species of gram-positive and gram-negative bacteria
- Acts as an alpha-glucosidase inhibitor
- Has in vivo anti-diabetic activity
- Purity of 98.75%
- White to off-white solid appearance
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Medchemexpress LLC EGFR-IN-70 | 2926716-96-1 | C31H36ClN5O5S | 1 ML
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EGFR-IN-70 (compound 18j) is a potent EGFR inhibitor with IC50 values of 23.6 nM for EGFRLR/TM/CS and 307.5 nM for EGFRWT. It exhibits anti-proliferative activity and suppresses the phosphorylation of EGFR. This compound is suitable for cancer research.
- Potent EGFR inhibitor with IC50 values of 23.6 nM (EGFRLR/TM/CS) and 307.5 nM (EGFRWT)
- Exhibits anti-proliferative activity
- Suppresses phosphorylation of the EGFR
- Suitable for cancer research
- Demonstrates antiproliferative activity against human A-431 cells (IC50 of 2.003 nM)
- Exhibits antiproliferative activity against mouse BaF3 cells expressing EGFR L858R/T790M/C797S mutant (IC50 of 0.036 μM)
- Suppresses phosphorylation of EGFR and downstream signaling ERK level
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Medchemexpress LLC DNA, d(P-thio)(C-C-T-G-G-C-c7rGm-G-G-G), sodium salt | 1682661-49-9 | DNA, d(P-thio)(C-C-T-G-G-C-c7rGm-G-G-G) | 1 MG
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ODN 24991 is a guanine-modified inhibitory oligonucleotide (INH-ODN) that functions as a TLR3, TLR7, and TLR9 (Toll-like receptor) inhibitor. It disrupts immune cell responses mediated by these Toll-like receptors.
- Guanine-modified inhibitory oligonucleotide (INH-ODN)
- Inhibits TLR3, TLR7, and TLR9 (Toll-like receptor)
- Disrupts immune cell immune responses mediated by TLR3, TLR7, and TLR9
- Derived from INH-ODN 2088
- Sequence: 5'-C-C-T-G-G-C-c7rGm-G-G-G-3'
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Medchemexpress LLC CHLOROPHENOL RED--D 25 mg
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CHLOROPHENOL RED--D 25MG
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Medchemexpress LLC S -N-GLYCIDYLPHTHAL 500G
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S -N-GLYCIDYLPHTHAL 500G
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Medchemexpress LLC 3-BENZYL-6-BROMO-1H- 1G
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3-BENZYL-6-BROMO-1H- 1G
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Medchemexpress LLC Bis(pinacolato)diborane | 73183-34-3 | 99.97% | C12H24B2O4 | 5 G
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Bis(pinacolato)diborane is an organoboron reagent that serves as a source of the [Bpin] moiety with pronounced nucleophilic character. It is utilized in the synthesis of various organoboranes, including organoboron compounds and arylboronates. This compound reacts with p-benzyne to produce tetraborylated products through a series of steps involving addition and 1,2-migration of the boryl group.
- Source of [Bpin] moiety with nucleophilic character
- Used in the synthesis of various organoboranes
- Reacts with p-benzyne to produce tetraborylated products
- Suitable for in vitro biological activity studies
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Medchemexpress LLC Tropisetron (Hydrochloride) | 105826-92-4 | MFCD02313825 | ≥98% | C17H21ClN2O2 | 100 MG
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Tropisetron (Hydrochloride) is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChR receptor agonist, with an IC50 of 70.1 nM for the 5-HT3 receptor. It possesses anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. This compound also reduces Aβ-induced hippocampal neuroinflammation.
- Effective neuroprotective agent.
- Acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChR receptor agonist.
- IC50 of 70.1 nM for the 5-HT3 receptor.
- Possesses anti-inflammatory properties and immune-regulating functions.
- Effectively alleviates symptoms associated with chemotherapy and post-surgery.
- Reduces Aβ-induced hippocampal neuroinflammation.
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Medchemexpress LLC Broussonin E | 90902-21-9 | 1 ML
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Broussonin E is a phenolic compound exhibiting anti-inflammatory activity. It suppresses inflammation by modulating the activation state of macrophages through inhibiting the ERK and p38 MAPK pathways, while enhancing the JAK2-STAT3 signaling pathway. This compound can be utilized for research related to inflammation-related diseases, such as atherosclerosis.
- Inhibits LPS (lipopolysaccharides)-stimulated phosphorylation of ERK and p38 MAPK at 20 μM for 3 hours.
- Activates janus kinase (JAK) 2 and signal transducer and activator of transcription (STAT) 3.
- Suppresses LPS-induced pro-inflammatory production in RAW264.7 cells (0-20 μM, 3 h), including TNF-α, IL-1β, IL-6, COX-2, and iNOS.
- Enhances the expression of anti-inflammatory mediators such as IL-10, CD206, and arginase-1 (Arg-1) in LPS-stimulated RAW264.7 cells.
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Medchemexpress LLC 50 BP DNA MARKER 250UL
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50 BP DNA MARKER 250UL
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Medchemexpress LLC AZOPHLOXINE 25G
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AZOPHLOXINE 25G
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Medchemexpress LLC 3-BENZYL-6-BROMO-1H- 250 mg
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3-BENZYL-6-BROMO-1H- 250MG
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Medchemexpress LLC POTASSIUM SODIUM TAR 25G
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POTASSIUM SODIUM TAR 25G
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Medchemexpress LLC CYTOSINE 250G
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CYTOSINE 250G
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Medchemexpress LLC L-PORRETINE 25G
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L-PORRETINE 25G
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