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Filtered Search Results
Ambeed AMBEED
5000866629 3-BROMO-2-IODOPHENOL 1GR
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Apexbio Technology LLC Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium 168555-66-6 10mM (in 1mL DMSO)
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Fosbretabulin (Combretastatin A4 Phosphate CA4P) Disodium (CAS 168555-66-6) is a water-soluble prodrug of combretastatin A4 that acts as a microtubule-destabilizing agent and tumor vascular targeting compound By binding to tubulin CA4P disrupts microtubule dynamics leading to endothelial cell cytoskeletal rearrangement impaired proliferation and migration In vitro CA4P induces myosin light chain phosphorylation actin stress fiber assembly and focal adhesion formation in endothelial cells resulting in vascular shutdown at sub-maximal tolerated doses In vivo studies show significant reduction of tumor functional vasculature and increased tumor necrosis supporting its application in tumor angiogenesis and vascular research
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431074 POTASSIUM SODIUM TAR 25G
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Aobchem AOBCHEM
5000864455 3-BROMO-5-IODOTOLUENE 1G
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eMolecules 22426-14-8 | 2-Bromo-1,10-phenanthroline | ChemScene | MFCD13152102 | 259.106 | C12H7BrN2 | 95.000 | Brc1ccc2ccc3cccnc3c2n1 | 25g | 572231202
2-Bromo-1,10-phenanthroline | ChemScene | 22426-14-8 | MFCD13152102 | 259.106 | C12H7BrN2 | 95.000 | Brc1ccc2ccc3cccnc3c2n1 | 25g | 572231202
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431080 L-PORRETINE 25G
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eMolecules 50270-27-4 | 2,4,6-Trichloropyrimidine-5-carbaldehyde | ChemScene | MFCD02257700 | 211.430 | C5HCl3N2O | 98.000 | Clc1nc(Cl)c(C=O)c(Cl)n1 | 100g | 572223343
2,4,6-Trichloropyrimidine-5-carbaldehyde | ChemScene | 50270-27-4 | MFCD02257700 | 211.430 | C5HCl3N2O | 98.000 | Clc1nc(Cl)c(C=O)c(Cl)n1 | 100g | 572223343
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000703515 GLYCOPYRRONIUM IMPUR 100G
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Medchemexpress LLC Nα,Nα-bis(carboxymethyl)-L-lysine | 113231-05-3 | 98.8% | 262.26 | C10H18N2O6 | 100 G
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Nα,Nα-Bis(carboxymethyl)-L-lysine is a research-grade amino acid derivative and potent competitive inhibitor of the bitter taste receptor TAS2R4 (IC50 = 59 nM). It is used in receptor pharmacology, structure-activity relationship studies, and biochemical assays requiring a selective TAS2R4 antagonist.
- Competitive inhibitor of bitter taste receptor 4 (IC50 = 59 nM).
- High purity suitable for biochemical and pharmacological assays (98.8%).
- Solid reagent compatible with standard solvents used in receptor studies.
- Molecular weight 262.26; molecular formula C10H18N2O6.
- Available in lab-scale quantities (for example, 100 g) for screening and validation.
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Apexbio Technology LLC Lomerizine HCl 101477-54-7 10mM (in 1mL DMSO)
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Lomerizine HCl (CAS 101477-54-7) is a small molecule antagonist of voltage-gated calcium channels exhibiting inhibitory activity on both L-type and T-type subtypes By modulating calcium influx across neuronal membranes lomerizine HCl is proposed to attenuate neuronal excitability associated with migraine pathophysiology This compound is utilized in biomedical research to investigate calcium channel function and the molecular mechanisms underlying migraine and related neurological disorders
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Apexbio Technology LLC Piperacillin Sodium 59703-84-3 10mM (in 1mL DMSO)
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Piperacillin Sodium (CAS 59703-84-3) is a small-molecule inhibitor targeting bacterial penicillin-binding proteins (PBPs) It is designed to inhibit cell wall biosynthesis thereby disrupting peptidoglycan cross-linking in bacteria Piperacillin Sodium exerts its biological activity primarily through irreversible binding to bacterial transpeptidases (PBPs) In in vitro studies Piperacillin Sodium demonstrates antibacterial inhibition with IC50 values typically ranging from 2 to 16 g/ml depending on microorganism sensitivity and experimental conditions Based on these pharmacological properties Piperacillin Sodium holds research potential in microbiological studies and the investigation of Pseudomonas aeruginosa infections
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Apexbio Technology LLC Prilocaine hydrochloride 1786-81-8 5g
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Prilocaine hydrochloride (CAS 1786-81-8) is a local anesthetic belonging to the amino amide class It functions by reversibly inhibiting voltage-gated sodium channels on neuronal cell membranes thereby blocking the initiation and propagation of nerve impulses This property makes it suitable for investigating neuronal excitability pain signaling and ion channel pharmacology in various preclinical models Prilocaine hydrochloride is commonly employed in studies requiring local anesthesia and serves as a reference compound for benchmarking novel anesthetic agents in research settings
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Medchemexpress LLC Bis(pinacolato)diborane | 73183-34-3 | 99.97% | C12H24B2O4 | 5 G
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Bis(pinacolato)diborane is an organoboron reagent that serves as a source of the [Bpin] moiety with pronounced nucleophilic character. It is utilized in the synthesis of various organoboranes, including organoboron compounds and arylboronates. This compound reacts with p-benzyne to produce tetraborylated products through a series of steps involving addition and 1,2-migration of the boryl group.
- Source of [Bpin] moiety with nucleophilic character
- Used in the synthesis of various organoboranes
- Reacts with p-benzyne to produce tetraborylated products
- Suitable for in vitro biological activity studies
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Apexbio Technology LLC Dicyclomine HCl 67-92-5 5g
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Dicyclomine Hydrochloride (CAS 67-92-5) is an orally active muscarinic acetylcholine receptor antagonist that primarily interacts with the M1 and M2 receptor subtypes It exhibits high binding affinity for the M1 subtype (Ki 5 nM) and moderate affinity for M2 receptors (Ki 55 nM) By inhibiting these receptors Dicyclomine HCl is utilized in studies investigating muscarinic receptor-mediated signal transduction Additionally it is commonly employed in pharmacological and pathophysiological research involving gastrointestinal smooth muscle spasm and related mechanisms
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Medchemexpress LLC N-desbutyl bupivacaine | 15883-20-2 | MFCD01701244 | 232.32 g/mol | C14H20N2O | 100 G
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N-Desbutyl bupivacaine is a major metabolite of bupivacaine used as a pharmacological reference compound. It is reported to act as an NMDA receptor inhibitor and an SCN5A antagonist.
- Cas number: 15883-20-2.
- Molecular formula: C14H20N2O.
- Molecular weight: 232.32 g/mol.
- Available pack sizes: 50 g, 100 g, larger quantities by request.
- Storage: 4°C, protect from light; in solvent: -80°C (6 months) or -20°C (1 month).
- Common use: drug metabolite and reference standard in pharmacology and metabolism studies.
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