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Filtered Search Results
Cambridge Isotope Laboratories Toluene (ring-D5 98%) 1 g
Toluene (ring-D5 98%) 1 g
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Medchemexpress LLC Zika virus E/envelope protein | 5 UG
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Recombinant Zika virus envelope (E) protein fragment (residues V593-K699) expressed in HEK293 cells with a His tag, supplied as a 0.22 μm filtered PBS solution for research use. The fragment is ~107 amino acids (~13 kDa) with endotoxin <1 EU/μg; store at -80°C and avoid repeated freeze-thaw cycles.
- Expressed in HEK293 human cells for mammalian post-translational modifications.
- His tag facilitates purification and detection.
- Supplied as a sterile 0.22 μm filtered PBS solution.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Fragment corresponds to residues V593-K699 (≈107 aa, ~13 kDa).
- Stable long-term at -80°C; avoid repeated freeze-thaw cycles.
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Medchemexpress LLC PROTAC BCR-ABL1 ligand 1 | 2489876-34-6 | 99.2% | 250 MG
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PROTAC BCR-ABL1 ligand 1, also known as compound GMB-475, is a PROTAC ligand that allosterically targets the BCR-ABL1 protein. It recruits the E3 ligase Von Hippel-Lindau, leading to the ubiquitination and subsequent degradation of BCR-ABL1. It demonstrates cell proliferation inhibition with IC50 values ranging from 0.37 μM to 1.98 μM for different BCR-ABL1 cell types and induces the degradation of BCR-ABL1 and c-ABL1, inhibiting downstream signaling via the STAT5 pathway in a dose- and time-dependent manner.
- Targets the BCR-ABL1 protein allosterically
- Recruits the E3 ligase Von Hippel-Lindau
- Leads to ubiquitination and degradation of BCR-ABL1
- Induces degradation of BCR-ABL1 and c-ABL1
- Inhibits downstream signaling via the STAT5 pathway
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Medchemexpress LLC IL-34 Mouse HEK293 100ug
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IL-34 protein is an important cytokine that promotes the proliferation survival and differentiation of monocytes and macrophages It plays a key role in innate immune responses and inflammatory processes by promoting the release of pro-inflammatory chemokines IL-34 Protein Mouse (HEK293 His) is the recombinant mouse-derived IL-34 protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC Thrombin Receptor/PA 10ug
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The thrombin receptor/PAR1 protein is a high-affinity receptor for activated thrombin that is coupled to G proteins to stimulate phosphoinositide hydrolysis This signaling mechanism suggests its involvement in platelet activation which is critical for hemostasis and thrombosis Thrombin Receptor/PAR1 Protein Human (HEK293 His) is the recombinant human-derived Thrombin Receptor/PAR1 protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC Tibenelast sodium | 105102-18-9 | MFCD00864802 | 99.7% | 288.30 g/mol | C13H13NaO4S | 1 ML
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Tibenelast sodium is a phosphodiesterase inhibitor supplied as a ready-to-use 10 mM solution in DMSO for research applications. It is identified by CAS 105102-18-9, with molecular formula C13H13NaO4S and a molecular weight of about 288.3 g/mol. The material is reported to have high purity and is intended for biochemical and cell-based studies.
- Ready-to-use 10 mM solution in DMSO, convenient for assay setup.
- High reported purity suitable for sensitive biochemical assays (refer to COA).
- Soluble in DMSO and compatible with common assay solvents.
- Suitable for phosphodiesterase inhibition and cellular pharmacology studies.
- Includes CAS identifier for unambiguous referencing.
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Medchemexpress LLC Bis-Tos-PEG7 | 69502-27-8 | 98.0% | C28H42O12S2 | 100 MG
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Bis-Tos-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Apexbio Technology LLC TUG-770 1402601-82-4 25mg
TUG-770 (CAS 1402601-82-4) is a potent agonist of the free fatty acid receptor 1 (FFA1/GPR40) a G protein-coupled receptor implicated in the enhancement of glucose-stimulated insulin secretion by pancreatic -cells TUG-770 demonstrates high affinity for FFA1 with an EC50 of 6 nM and over 150-fold selectivity compared to FFA4 as well as high selectivity over other receptors and transporters In INS-1E rat -cell lines TUG-770 promotes insulin secretion in the presence of elevated glucose Pharmacokinetic studies in mice indicate favorable oral absorption and bioavailability with dose-dependent reductions in blood glucose during glucose tolerance tests TUG-770 is a valuable tool for investigating FFA1-mediated pathways and glucose homeostasis in metabolic research
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Medchemexpress LLC hsa-miR-145-5p mimic 20nmol | 20nmol
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hsa-miR-145-5p mimics are small chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity
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Alkali Scientific bis Acrylamide, 250 G
Bis Acrylamide, 250 G is a crosslinking agent used in the preparation of polyacrylamide gels for applications in electrophoresis, gel filtration, and molecular biology studies. The 250g package is ideal for medium-volume research laboratories that require bis acrylamide for regular gel preparation. Bis Acrylamide forms crosslinks with acrylamide to create a stable gel matrix, providing the mechanical strength necessary for separating proteins, DNA, and other molecules by size. The powder form ensures easy customization of crosslinking density based on experimental requirements, offering flexibility for various types of gel electrophoresis, including SDS-PAGE and native PAGE.
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Medchemexpress LLC Hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine | 4719-04-4 | MFCD01678788 | >=96.0% | 219.28 g/mol | C9H21N3O3 | 500 G
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Triazinetriethanol (hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine) is a hexahydro triazine derivative used as a chemical reagent and intermediate. Supplied as a colorless to light-yellow liquid, it is characterized by certificate of analysis data for identity and composition.
- CAS registry number 4719-04-4.
- High purity: ≥96.0% (certificate of analysis).
- Chemical formula C9H21N3O3; molecular weight 219.28 g/mol.
- Physical form: colorless to light-yellow liquid; density ≈1.157 g/mL at 20 °C.
- Analytical parameters reported: refractive index, pH, ethanolamine and formaldehyde content.
- Storage recommended refrigerated or frozen for extended stability.
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Medchemexpress LLC C2/Complement C2 Mo 5ug
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Complement C2 is a component of the classical pathway of the complement system and is cleaved by activated factor C1 resulting in the formation of two distinct fragments C2b and C2a The subsequent serine protease activity of C2a is critical for its subsequent interaction with the complement factor C4b leading to the formation of C3 or C5 convertase C2/Complement C2 Protein Mouse (HEK293 His) is the recombinant mouse-derived C2/Complement C2 protein expressed by HEK293 with C-His labeled tag
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Alkali Scientific Acrylamide/bis Acrylamide, 19:1 Ratio Solution, Liquid, 1 L
Acrylamide/bis Acrylamide, 19:1 Ratio Solution, Liquid, 1 L, is a ready-to-use solution ideal for polyacrylamide gel electrophoresis (PAGE). The 19:1 ratio ensures optimal gel formation for separating larger proteins and biomolecules. This solution is pre-mixed, saving time and reducing the need for precise measurements during gel preparation. It is widely used in molecular biology, biochemistry, and protein analysis to achieve high-resolution separation of proteins based on size. The solution is convenient for researchers who require reliable and reproducible results in electrophoresis experiments, particularly in proteomics and enzymology studies.
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Medchemexpress LLC 1-hydroxy-7-azabenzotriazole | 39968-33-7 | MFCD00210053 | 100g
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HOAT is a commonly used peptide bond forming agent that may become an impurity in drug synthesis but is not mutagenic HOAT can be used for peptide fragment polycondensation and can also inhibit the racemization of peptide polycondensation[1]
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Alkali Scientific SOB Broth, 1 Kg
SOB Broth (Standard Oxytetracycline Broth) is a microbiological growth medium used to support the growth of a variety of bacterial species. The 1 kg package is ideal for large-scale microbial growth studies and testing in clinical, pharmaceutical, and environmental laboratories. This broth is particularly effective in the recovery and cultivation of organisms from water and environmental samples. The medium contains a broad-spectrum antibiotic (oxytetracycline) that suppresses unwanted bacterial growth, allowing researchers to focus on the target organisms. SOB Broth is commonly used in research, diagnostics, and quality control testing to isolate and enumerate specific bacterial populations from contaminated samples.
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