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Filtered Search Results
Medchemexpress LLC GSK 3008348 hydrochloride | 1629249-40-6 | 98.0% | 10 MG
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GSK 3008348 hydrochloride is a small-molecule antagonist of the αvβ6 integrin used as a research tool to study integrin-mediated TGF-β activation, pulmonary fibrosis, and integrin-dependent viral entry. It exhibits low-nanomolar activity in cell assays and is supplied as a hydrochloride salt for laboratory research.
- High potency against αvβ6 integrin with low-nanomolar IC50.
- Selective inhibition of αv-containing integrins in cell assays.
- Suitable for pulmonary fibrosis and oncology research applications.
- Supplied as a hydrochloride salt with recommended storage conditions.
- Provided in research-scale pack sizes for laboratory use.
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![Medchemexpress LLC Ethanol, 2,2'-[iminobis(2,1-ethanediyloxy)]bis- | 54384-47-3 | 97.0% | 193.24 g/mol | C8H19NO4 | 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202012.png-250.jpg)
Medchemexpress LLC Ethanol, 2,2'-[iminobis(2,1-ethanediyloxy)]bis- | 54384-47-3 | 97.0% | 193.24 g/mol | C8H19NO4 | 10 G
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NH-bis-PEG2 is a non-cleavable, two-unit polyethylene glycol (PEG) linker with terminal primary amine functionality supplied as a solid for research use. It is designed to serve as a short, flexible spacer in the synthesis of antibody-drug conjugates (ADCs) and proteolysis-targeting chimeras (PROTACs), facilitating conjugation between small molecules and biomolecules.
- Non-cleavable two-unit PEG spacer.
- Terminal primary amine for conjugation chemistry.
- Short, flexible linker suitable for ADC and PROTAC synthesis.
- High purity suitable for research applications.
- Available in multiple pack sizes, including 10 G.
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Medchemexpress LLC N-hydroxysulfosuccinimide (sodium) | 106627-54-7 | MFCD00043100 | 100.0% | 217.13 g/mol | C4H4NNaO6S | 100 G
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N-hydroxysulfosuccinimide (sodium) is the sodium salt of sulfo-N-hydroxysuccinimide, supplied as a white to off-white solid. It serves as a water-soluble activated ester reagent for preparing amine-reactive sulfo-NHS esters for protein modification and bioconjugation, and is used as a non-cleavable linker in antibody-drug conjugate synthesis. Store sealed and protected from moisture.
- Water-soluble activated ester for efficient amine coupling.
- Suitable for protein modification and bioconjugation.
- Used as a non-cleavable linker in antibody-drug conjugate synthesis.
- High purity (99.99%).
- White to off-white solid, stable when stored sealed and dry at 4°C.
- Molecular weight 217.13 g/mol; formula C4H4NNaO6S.
- Available in solid pack sizes up to 100 g.
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Medchemexpress LLC Tandospirone impurit 25g
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Tandospirone impurity 4 is an impurity of Tandospirone (HY-14558)
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Ambeed Bis R 1phenylethyl amine
Bis[(R)-1-phenylethyl]amine, 23294-41-9, 98%
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Medchemexpress LLC Fluo-3-pentaacetoxymethyl ester | 121714-22-5 | ≥99.0% | 1 MG
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Fluo-3 AM is a fluorescent Ca2+ chelator with high affinity for calcium. It can specifically identify intracellular calcium ions, exhibiting high sensitivity and low cytotoxicity. The increased AM acetylmethyl ester allows it to enter the cell effectively, and after being cleaved by intracellular esterase, it remains in the cell to bind with calcium ions, producing strong fluorescence.
- Fluorescent Ca2+ chelator.
- High affinity for calcium.
- Specifically identifies intracellular calcium ions.
- High sensitivity.
- Low cytotoxicity.
- Increased AM acetylmethyl ester for good cellular penetration.
- Produces strong fluorescence upon binding to calcium ions.
- Can be used in calcium flux analysis.
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Medchemexpress LLC Chloroxylenol (p-Chloro-m-xylenol) | 88-04-0 | 99.5% | 25 G
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Chloroxylenol is a broad-spectrum antibacterial agent effective against bacteria, algae, fungi, and viruses. It inhibits the viability, proliferation, migration, invasion, and sphere formation, and induces apoptosis in HCT116 and SW480 cells by inhibiting the Wnt/β-catenin signaling pathway.
- Inhibits nuclear translocation of β-catenin in HCT116 and SW480 cells
- Inhibits the growth of CRC organoids
- Decreases mRNA levels of Axin2, Survivin, and LGR5 in HCT116 and SW480 CRC cells
- Inhibits tumor growth in a MC38 cell xenograft model
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Medchemexpress LLC Cefmetazole sodium | 56796-39-5 | 99.5% | 1 ML
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Cefmetazole sodium is a semisynthetic cephamycin antibiotic that exhibits broad-spectrum antibacterial activity against gram-positive, gram-negative, and anaerobic bacteria. It functions by binding to penicillin binding proteins (PBPs), which interferes with the biosynthesis of bacterial cell walls. This product is intended for research purposes related to gynecologic, intraabdominal, urinary tract, respiratory tract, and skin and soft tissue infections.
- Semisynthetic cephamycin antibiotic.
- Broad-spectrum antibacterial activity.
- Effective against gram-positive, gram-negative, and anaerobic bacteria.
- Interferes with bacterial cell wall biosynthesis by binding to penicillin binding proteins (PBPs).
- Used for research into gynecologic, intraabdominal, urinary tract, respiratory tract, and skin and soft tissue infections.
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Medchemexpress LLC Sodium methylarsonate | 2163-80-6 | MFCD00072437 | 95.0% | 161.95 g/mol | CH4AsNaO3 | 1mg
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Sodium methylarsonate (Monosodium methylarsonate) is an organoarsenic compound with environmental toxicity that can be used as a herbicide to control weeds Sodium methylarsonate interferes with plant metabolic processes particularly by hindering photosynthesis and protein synthesis ultimately leading to plant death Additionally sodium methylarsonate can induce the production of metallothioneins (MTs) in fish[1]
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eMolecules 2-TERT-BUTOXYCARBONYLA 100G
5000280407 2-TERT-BUTOXYCARBONYLA 100G
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Medchemexpress LLC Sardomozide dihydrochloride | 138794-73-7 | 99.73% | 303.19 | 100 MG
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Sardomozide dihydrochloride is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM. It is for research use only. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When CHO/664 cells are grown in the presence of Sardomozide and treated with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to parental CHO cells.
- S-adenosylmethionine decarboxylase (SAMDC) inhibitor
- IC50 of 5 nM
- Reduces intracellular SAMDC activity to 10% of control after 48 h treatment with 3 μM
- Prevents vacuole formation in CHO/664 cells when treated with DENSPM
- Inhibits growth of CHO/664 cells
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Medchemexpress LLC Cyromazine | 66215-27-8 | 99.8% | 25 G
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Cyromazine is a triazine insect growth regulator, functioning as an insecticide and acaricide. This cyclopropyl derivative of melamine affects the nervous system of immature larval stages of insects. It can reduce germ cells by interfering with the Ecdysone signaling pathway and may induce renal toxicity, which can be mitigated by green tea extract.
- Functions as an insecticide and acaricide.
- Affects the nervous system of immature larval insects.
- Interferes with the Ecdysone signaling pathway.
- May decrease germline stem cells and cystoblasts.
- Inhibits primordial germ cells in larval ovaries.
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Medchemexpress LLC Cellulose, carboxymethyl ether | 9000-11-7 | 25 G
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Cellulose, carboxymethyl ether | 9000-11-7 | 25 G
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Medchemexpress LLC Deoxyarbutin | 53936-56-4 | HY-B1461 | 99.92% | 25 G
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Deoxyarbutin is an orally active tyrosinase inhibitor that can promote apoptosis of melanoma cells, enhance the vitality of mouse acinar cells, and has skin whitening and anti-tumor activity.
- Orally active tyrosinase inhibitor.
- Promotes apoptosis of melanoma cells.
- Enhances vitality of mouse acinar cells.
- Possesses skin whitening activity.
- Shows anti-tumor activity.
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Medchemexpress LLC Reactive blue 19 | 2580-78-1 | 25 G
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Reactive Blue 19 is an anthraquinone dye primarily used in the textile industry for dyeing cellulose fibers. It is also utilized as a starting material for polymer dye production. While effective for dyeing, it is considered a toxic and undegradable organic pollutant that can pose risks to human health and aquatic life.
- Used in textile industry
- Applicable for dyeing cellulose fibers
- Utilized in diagnostic assay manufacturing, hematology, and histology
- Can serve as a starting material for polymer dyes
- Known water pollutant, decolourization can be achieved via photodegradation
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