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Filtered Search Results
Medchemexpress LLC OS-3-106 25mg | 1580000-17-4 | 450.60 g/mol | C25H30N4O2S | 25 MG
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OS-3-106 is a potent, blood-brain barrier penetrant dopamine D3 receptor (D3R) agonist with high affinity (Ki = 0.2 nM) and approximately 115-fold selectivity over D2R. It is supplied as a purified research compound for in vitro and in vivo pharmacology studies.
- High affinity D3R agonist (Ki = 0.2 nM).
- Approximately 115-fold selectivity for D3R versus D2R.
- Blood-brain barrier penetrant, suitable for CNS studies.
- High purity (97.03%).
- Supplied as a small-quantity research pack (25 mg).
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5000885029 1-BENZYL 3-ETHYL 4-OXOPY 10G
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Medchemexpress LLC I-191 | 1690172-25-8 | 99.1% | 423.48 | C23H26FN5O2 | 1 ML
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I-191 is a potent, selective antagonist of protease-activated receptor 2 (PAR2) for research use. It attenuates PAR2-mediated intracellular signaling, including Ca2+ release and ERK1/2 phosphorylation, and is supplied as a high-purity solid or a ready-to-use DMSO solution.
- Molecular weight: 423.48 g/mol.
- Chemical formula: C23H26FN5O2.
- CAS number: 1690172-25-8.
- Purity: 99.14%.
- Form and color: solid; white to gray.
- Solubility: DMSO 8.33 mg/mL (19.67 mM); ultrasonic agitation recommended.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years) or -20°C (1 year).
- Supplied quantities: 10 mM, 1 mL solution; solids 5 mg-100 mg (larger sizes available).
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Medchemexpress LLC Bruton's tyrosine kinase (BTK), human, C481S, biotinylated | >90.0% | 50UG
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Recombinant human Bruton's tyrosine kinase (BTK) C481S mutant supplied as an active, site-specifically biotinylated protein with N-terminal His and Avi tags. Expressed in Sf9 insect cells and provided as a 50 μg formulation in a filtered buffered solution. Purity is greater than 90% and molecular weight is approximately 80.4 kDa; store at -80°C and avoid repeated freeze-thaw cycles.
- Expressed in Sf9 insect cells.
- Site-specific biotinylation with N-terminal His and Avi tags.
- Active enzyme activity confirmed by off-chip mobility shift assay.
- Contains C481S mutation to model inhibitor resistance.
- Supplied as a 50 μg aliquot in filtered buffered solution.
- Purity greater than 90% as determined by reducing SDS-PAGE.
- Store at -80°C; stable short-term at -20°C after opening; avoid repeated freeze-thaw.
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Medchemexpress LLC 1-Bromo-2-chlorobenzene-d4 | 1219795-51-3 | 195.48 | 100 MG
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1-Bromo-2-chlorobenzene-d4 is the deuterium labeled version of 1-Bromo-2-chlorobenzene. This product is intended solely for research purposes and is not sold for patient use. Incorporating stable heavy isotopes like deuterium into drug molecules allows for their use as tracers for quantitation during the drug development process. Deuteration is also noted for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- It is the deuterium labeled form of 1-bromo-2-chlorobenzene.
- Can be used as a tracer.
- Suitable for use as an internal standard for quantitative analysis by methods such as NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
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5000885404 2-N-METHYLAMINOETHYL CHL 25G
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Medchemexpress LLC 5-Bromo-2-iodobenzoic acid | 21740-00-1 | 326.91 | 50 G
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5-Bromo-2-iodobenzoic acid is a biochemical reagent used as a biological material or organic compound for life science-related research.
- Used as a biological material
- Used as an organic compound for life science-related research
- Appears as an off-white to light brown solid
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Medchemexpress LLC Benzhydrol | 91-01-0 | 184.24 | 500 G
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Benzhydrol (Diphenylmethanol) is a biochemical reagent used as a biological material or organic compound for life science-related research. It is for research use only.
- Used as intermediates in pharmaceuticals (including antihistamines), agrochemicals, perfumes, and other organic compounds.
- Used as a fixative in the perfume industry.
- Involved in polymerization reactions as a terminating group.
- Used as a precursor to prepare modafinil, benztropine, and diphehydramine.
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5000885255 26-DIFLUOROBENZYLHYDRAZI 5G
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Medchemexpress LLC 2-chloro-1-[2-[3-(trifluoromethyl)anilino]phenyl]ethanone | 2378626-29-8 | 99.7% | 313.70 g/mol | C15H11ClF3NO | 10MM 1ML
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TED-347 is a potent, irreversible, covalent, allosteric inhibitor of the YAP-TEAD protein-protein interaction that blocks TEAD transcriptional activity and shows reported antitumor effects in preclinical studies. Reported biochemical activity includes an EC50 of 5.9 μM for TEAD4-Yap1 and a Ki of approximately 10.3 μM; the compound covalently modifies Cys-367 in TEAD4.
- Irreversible covalent inhibitor of YAP-TEAD interaction.
- Reported EC50 of 5.9 μM (TEAD4-Yap1) and Ki ≈ 10.3 μM.
- Covalently modifies Cys-367 in TEAD4.
- Demonstrated antitumor activity in preclinical studies.
- Available as DMSO solution and as solid powder for formulation.
- Molecular formula C15H11ClF3NO; molecular weight 313.70 g/mol.
- High purity suitable for research applications (reported ≥98%).
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Medchemexpress LLC Decyltrimethylammonium bromide | 2082-84-0 | MFCD00041973 | 98.0% | 280.29 | 25 G
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Decyltrimethylammonium bromide is a quaternary ammonium salt comprising a decyltrimethylammonium cation and a bromide anion. This biochemical reagent is intended for life science-related research as a biological material or organic compound, with a role as a surfactant. It is for research use only and not sold to patients.
- Solid form
- White to light yellow color
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Alkali Scientific Timentin [Ticarcillin Disodium Salt/Potassium Clavulanate Mixture 15:1 Ratio], 100 G
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Timentin (100g) combines Ticarcillin Disodium Salt and Potassium Clavulanate in a 15:1 ratio to offer broad-spectrum antibacterial activity. The Ticarcillin component disrupts bacterial cell wall synthesis, while Potassium Clavulanate prevents bacterial resistance by inhibiting beta-lactamase enzymes. This 100g size is ideal for preparing larger volumes of solution for high-throughput testing or clinical treatments. Timentin is highly effective against Gram-negative and Gram-positive organisms, especially those resistant to other antibiotics. It is commonly used in treating complex infections such as sepsis, pneumonia, and intra-abdominal infections in hospital settings.
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Alkali Scientific MacConkey Agar, 1 Kg
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MacConkey Agar is a selective culture medium designed for isolating and differentiating Gram-negative bacteria, particularly enteric organisms. It contains bile salts and crystal violet to inhibit the growth of Gram-positive bacteria, allowing the growth of only Gram-negative organisms. The medium also includes lactose and a pH indicator, which differentiates lactose fermenters from non-fermenters based on color changes. Lactose fermenters appear pink or red, while non-fermenters remain colorless or pale. MacConkey Agar is widely used in microbiological laboratories for the isolation and differentiation of enteric pathogens like Escherichia coli and Salmonella from clinical and environmental samples.
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Alkali Scientific Agarose HR, High Resolution, 500 Grams
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Agarose HR (High Resolution) is a specialized agarose used in DNA gel electrophoresis for sharp band separation. With a high-resolution profile, it offers superior performance in separating small DNA fragments, providing clearer and more distinct bands than standard agarose. This 500g package is ideal for labs that frequently perform high-resolution separation for genetic analysis, PCR applications, or sequencing. Agarose HR is designed to maintain structural integrity during the gel preparation process, ensuring precise results in applications such as DNA analysis, restriction digestion analysis, and other molecular biology applications requiring high-fidelity gel electrophoresis.
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Medchemexpress LLC E/Envelope Dengue v 10ug
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E/Envelope Protein Dengue virus 2 (429a a sf9 His) is the recombinant Virus-derived E/Envelope protein expressed by Sf9 insect cells with C-His labeled tag
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