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Filtered Search Results
Medchemexpress LLC Retaspimycin hydrochloride | 857402-63-2 | 624.17 | C31H46ClN3O8 | 1 ML
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Retaspimycin hydrochloride is a small-molecule inhibitor of heat shock protein 90 (Hsp90) provided as a concentrated DMSO stock for research use. It exhibits submicromolar activity against HSP90 and GRP94 and is supplied with guidance on solubility and storage for experimental applications.
- Potent Hsp90 and GRP94 inhibitor with reported EC50 of 119 nM.
- Provided as a 10 mM solution in DMSO (1 mL) for convenient stock preparation.
- Molecular weight 624.17 and formula C31H46ClN3O8 for accurate dosing calculations.
- High solubility in DMSO and documented in vivo formulation options.
- Recommended storage at -20°C (solid) and -80°C in solution for long-term stability.
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Medchemexpress LLC 3-Aminophenylacetic acid | 14338-36-4 | 151.16 | 10 G
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3-Aminophenylacetic acid is an organic compound.
- It is an organic compound.
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Medchemexpress LLC Palbociclib hydrochloride | 571189-11-2 | 99.9% | C24H30ClN7O2 | 100 MG
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Palbociclib hydrochloride is an orally active, selective inhibitor of CDK4 and CDK6, with IC50 values of 11 nM and 16 nM respectively. It exhibits potent anti-proliferative activity and is capable of inducing cell cycle arrest in various cancer cells. This compound is suitable for research applications concerning HR-positive and HER2-negative breast cancer, as well as hepatocellular carcinoma.
- Selective CDK4 and CDK6 inhibitor.
- Potent anti-proliferative activity.
- Induces cell cycle arrest in cancer cells.
- Used in research for HR-positive and HER2-negative breast cancer.
- Used in research for hepatocellular carcinoma.
- Demonstrates efficacy in inhibiting retinoblastoma phosphorylation.
- Effective in various in vitro cell proliferation assays.
- Shows potent antitumour effects in in vivo animal models.
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Medchemexpress LLC Rimantadine hydrochloride | 1501-84-4 | 98.0% | 5 G
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Rimantadine hydrochloride is an orally active inhibitor for M2 protein, designed for research applications. It functions by blocking hydrogen ion channel activity, thereby preventing viral entry and replication, and demonstrating broad-spectrum antiviral effects. This compound is intended for research use only.
- Orally active M2 protein inhibitor
- Blocks hydrogen ion channel activity
- Prevents virus entry and replication
- Exhibits broad-spectrum antiviral activity
- Inhibits RNA levels of hepatitis A virus (HAV) in Huh7 and IHH cells
- Induces autophagy in HAV-infected Huh7 cells
- Exhibits anti-infectious activity in H3N2-infected mouse models
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Medchemexpress LLC Pevonedistat hydrochloride | 1160295-21-5 | MFCD17215670 | 99.2% | 480.0 g/mol | C21H26ClN5O4S | 50 MG
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Pevonedistat hydrochloride is the hydrochloride salt of pevonedistat, a small-molecule inhibitor of the NEDD8-activating enzyme (NAE) used in preclinical research to probe ubiquitin-like protein modification, cell-cycle regulation, and anticancer mechanisms.
- Potent, selective NAE inhibitor for mechanistic and pharmacology studies.
- Hydrochloride salt with formula C21H26ClN5O4S.
- Molecular weight 480.0 g/mol.
- High purity suitable for research applications (~99%).
- Soluble in DMSO; limited solubility in water.
- Supplied as a 50 mg solid for small-scale experiments.
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Medchemexpress LLC Sotuletinib hydrochloride | 2222138-31-8 | 99.43% | 25 MG
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Sotuletinib hydrochloride is a potent, selective, orally active, and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM. It demonstrates more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs. This compound is valuable for research involving microglia depletion, and studies related to tumor and CNS-related diseases.
- Potent, selective, orally active, and brain-penetrant CSF-1R (c-Fms) inhibitor
- IC50 of 1 nM
- High selectivity, more than 1,000-fold against closest receptor tyrosine kinase homologs
- Useful for microglia depletion studies
- Applicable in tumor and CNS-related disease research
- Inhibits CSF-1-dependent proliferation in bone marrow-derived macrophages
- Decreases CSF-1R phosphorylation
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Medchemexpress LLC Flibanserin (hydrochloride) (propan-2-ol) (hydrate) | 99.0% | C20H22ClF3N4O.0.5C3H8O.0.5H2O | 25 MG
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Flibanserin hydrochloride (propan-2-ol) hydrate is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist. It also binds to dopamine D4 receptors, demonstrating anti-depression and anti-anxiety effects. This compound is utilized in research for hypoactive sexual desire disorder (HSDD).
- Orally active serotonin 5-HT1A receptor agonist
- 5-HT2A receptor antagonist
- Binds to dopamine D4 receptors
- Shows anti-depression and anti-anxiety effects
- Used in research for hypoactive sexual desire disorder (HSDD)
- Non-toxic up to 100 μM in cell viability assays
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Aobchem 2 4-Difluoro-6-iodophenol | ≥97% | CAS 551002-42-7 | C6H3F2IO | 250mg
2 4-Difluoro-6-iodophenol | ≥97% | CAS 551002-42-7 | C6H3F2IO | 250mg
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Aobchem 6-Bromo-3-fluoro-2-iodophenol | 97% | CAS 1805191-96-1 | C6H3BrFIO | 250mg
6-Bromo-3-fluoro-2-iodophenol | 97% | CAS 1805191-96-1 | C6H3BrFIO | 250mg
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Aobchem 4-Chloro-2-fluoro-3-iodophenol | 97% | CAS 2386540-76-5 | C6H3ClFIO | 250mg
4-Chloro-2-fluoro-3-iodophenol | 97% | CAS 2386540-76-5 | C6H3ClFIO | 250mg
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Aobchem 6-Chloro-2-fluoro-3-iodophenol | 95% | CAS 2384343-94-4 | C6H3ClFIO | 250mg
6-Chloro-2-fluoro-3-iodophenol | 95% | CAS 2384343-94-4 | C6H3ClFIO | 250mg
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Aobchem 2-Methoxy-5-iodophenol | ≥97% | CAS 160257-85-2 | C7H7IO2 | 250mg
2-Methoxy-5-iodophenol | ≥97% | CAS 160257-85-2 | C7H7IO2 | 250mg
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Aobchem 6-Bromo-3-fluoro-2-iodophenol | 97% | CAS 1805191-96-1 | C6H3BrFIO | 1g
6-Bromo-3-fluoro-2-iodophenol | 97% | CAS 1805191-96-1 | C6H3BrFIO | 1g
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Aobchem 2-Bromo-4-iodophenol | ≥95% | CAS 133430-98-5 | C6H4BrIO | 500mg
2-Bromo-4-iodophenol | ≥95% | CAS 133430-98-5 | C6H4BrIO | 500mg
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Chem-Impex International, Inc. 2-Bromo-4-fluorophenol | MFCD00010614 | 100G
2-Bromo-4-fluorophenol, MFCD00010614, 100G
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