Halophenols

Medchemexpress LLC Gemcitabine Hydrochloride | 122111-03-9 | 99.9% | C9H11F2N3O4 · HCl | 5 G

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Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. It works by inhibiting DNA synthesis and repair, ultimately leading to autophagy and apoptosis.

• Targets DNA synthesis.
• Inhibits the growth of various cancer cell lines, including BxPC-3, Mia Paca-2, PANC-1, PL-45, and AsPC-1.
• Effectively kills both mouse and human senescent cells in vitro.
• Demonstrates increased survival time in mouse models when combined with DMAPT.
• Can be administered via endotracheal spray in rats with lower toxicity compared to oral administration at certain dosages.

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Medchemexpress LLC GSK 3008348 hydrochloride | 1629249-40-6 | 99.86% | 524.109 g/mol | 5 MG

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GSK 3008348 hydrochloride is a small molecule antagonist of integrin αvβ6 with IC50 values for αvβ6, αvβ1, αvβ3, αvβ5, and αvβ8 of 1.50, 2.83, 12.53, 4.00, and 2.26 nM, respectively. It targets the αvβ6 integrin, inhibits TGF-β activation, and thereby alleviates the fibrotic process. It also prevents the binding of the foot-and-mouth disease virus (FMDV) to the αvβ6 integrin receptor on the surface of host cells, inhibiting viral entry. It is suitable for research on pulmonary fibrosis and various types of cancer.

• Small molecule antagonist of integrin αvβ6.
• Targets αvβ6 integrin.
• Inhibits TGF-β activation, which helps alleviate fibrotic processes.
• Prevents foot-and-mouth disease virus (FMDV) binding to the αvβ6 integrin receptor, thereby inhibiting viral entry.
• Can be utilized in research concerning pulmonary fibrosis and various forms of cancer.

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eMolecules​ 288315-03-7 | 3,3-DIFLUOROAZETIDINE HCL | AstaTech | MFCD05663714 | 129.530 | C3H6ClF2N | 95.000 | Cl.FC1(F)CNC1 | 10g | 397208639

3,3-DIFLUOROAZETIDINE HCL | AstaTech | 288315-03-7 | MFCD05663714 | 129.530 | C3H6ClF2N | 95.000 | Cl.FC1(F)CNC1 | 10g | 397208639

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