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Filtered Search Results
Medchemexpress LLC PF-06815345 hydrochloride | 2334434-49-8 | 98.2% | 634.49 | 100 MG
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PF-06815345 hydrochloride is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 μM. PF-06815345 hydrochloride significantly decreases the PCSK9 level in vivo in mouse.
- Orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9).
- IC50 value of 13.4 μM.
- Significantly decreases the PCSK9 level in vivo in mouse.
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Medchemexpress LLC PF-00356231 hydrochloride | 820223-77-6 | 99.5% | 464.96 | 25 MG
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PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). It forms a complex with MMP-12 and also demonstrates potency against MMP-13, MMP-8, MMP-9, and MMP-3.
- Specific inhibitor of MMP-12
- Non-peptidic, non-zinc chelating ligand
- Potent against MMP-13, MMP-8, MMP-9, and MMP-3
- For research use only
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Medchemexpress LLC Venlafaxine hydrochloride | 99300-78-4 | 99.8% | 25 MG
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Venlafaxine hydrochloride is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. It is an antidepressant used for research purposes only.
- Potent serotonin/norepinephrine reuptake dual inhibitor
- Antidepressant for research purposes
- Inhibits [3H]-5-HT reuptake in human SERT transfected cells (IC50: 0.2 μM)
- Inhibits [3H]-NE reuptake in human NET transfected cells (IC50: 2.55 μM)
- Inhibits human DAT expressed in HEK293 cells by neurotransmitter reuptake assay (IC50: 15700 nM)
- Dose-dependently blocks depletion of norepinephrine levels in rat hypothalamus
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Medchemexpress LLC 3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) | 3722-51-8 | 98.4% | 212.20 | 50 G
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3-Hydroxyxanthone is a xanthone compound. It inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs) and also inhibits TNF-alpha induced ICAM-1 expression.
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Medchemexpress LLC Pilsicainide hydrochloride | 88069-49-2 | 99.9% | 308.85 | C17H25ClN2O | 5 MG
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Pilsicainide hydrochloride is an orally active sodium channel blocker used in research on cardiac electrophysiology. It functions as a potent class Ic antiarrhythmic agent and is provided as a solid suitable for laboratory studies.
- Orally active sodium channel blocker.
- Potent class Ic antiarrhythmic agent.
- High purity (99.94%).
- White to off-white solid appearance.
- Available in small-mass packages for analytical and pharmacological work.
- Stable when stored under recommended conditions.
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Medchemexpress LLC MRS 2211 sodium hydrate | 1197030-56-0 | MFCD09038558 | 97.9% | 470.69 g/mol | C14H13ClN4NaO9P | 5 MG
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MRS 2211 sodium hydrate is the sodium salt hydrate form of a selective competitive P2Y13 receptor antagonist supplied for research use. It is provided as a brown to reddish-brown solid with reported purity of 97.9%, intended for in vitro pharmacology and biochemical studies of purinergic signaling.
- Selective P2Y13 receptor antagonism (pIC50 ≈ 5.97).
- High reported purity for reliable experimental results.
- Solid form suitable for dissolution and formulation in common solvents.
- Available in small quantities for exploratory and pilot studies.
- Recommended sealed, cold storage to minimize degradation.
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![Medchemexpress LLC 2-[2-[2-(5-bromo-2-methoxyphenyl)ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole hydrochloride | 1706524-94-8 | MFCD28133377 | 99.3% | 413.71 g·mol⁻¹ | C18H19BrClFN2O | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000263559.png-250.jpg)
Medchemexpress LLC 2-[2-[2-(5-bromo-2-methoxyphenyl)ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole hydrochloride | 1706524-94-8 | MFCD28133377 | 99.3% | 413.71 g·mol⁻¹ | C18H19BrClFN2O | 5 MG
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ML-00253764 hydrochloride is the hydrochloride salt of a brain-penetrant, nonpeptidic antagonist of the melanocortin 4 receptor (MC4R) used in pharmacological research. It exhibits submicromolar binding and functional inhibition of MC4R, is supplied as a high-purity solid, and is intended for in vitro and in vivo studies when handled and stored according to manufacturer recommendations.
- Brain-penetrant, nonpeptidic melanocortin 4 receptor (MC4R) antagonist.
- Submicromolar potency: Ki = 0.16 μM, IC50 = 0.103 μM.
- High purity (~99.3%) suitable for research applications.
- Hydrochloride salt form for improved handling and solubility.
- Solid, off-white to light yellow appearance; easy to weigh and formulate.
- Recommended for in vitro and in vivo pharmacology with proper storage.
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Medchemexpress LLC Mavorixafor hydrochloride | 880549-30-4 | MFCD11977316 | 99.1% | 385.93 g·mol⁻1 | C21H28ClN5 | 10 MG
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Mavorixafor hydrochloride is a potent, selective CXCR4 antagonist supplied as the hydrochloride salt for research use. It is provided as a viscous liquid with high purity and is intended for in vitro and preclinical studies of CXCR4 signaling and related disease models.
- High purity: 99.1%.
- Molecular weight: 385.93 g·mol⁻1.
- Cas number: 880549-30-4.
- Physical form: viscous liquid, light yellow to brown.
- Storage: store at -20 °C, sealed, protect from moisture and light.
- Application: research into CXCR4 biology and WHIM syndrome models.
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Medchemexpress LLC Tiviciclovir hydrochloride | 00-00-0 | 99.4% | 275.69 g/mol | C9H14ClN5O3 | 5 MG
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Tiviciclovir hydrochloride is an antiviral guanosine analog used as a hepatitis B virus (HBV) inhibitor in preclinical research. It is supplied as the hydrochloride salt, with molecular formula C9H14ClN5O3 and molecular weight 275.69 g/mol. The product listing and datasheet include solubility, formulation guidance, storage recommendations, and batch-specific purity information for laboratory use.
- Has antiviral activity against hepatitis B virus.
- Provided as a hydrochloride salt to aid solubility.
- Soluble in DMSO at 100 mg/mL; ultrasonic aid recommended.
- Formulation guidance for in vivo dosing is included.
- Storage recommendations for dry material and solutions are provided.
- Includes batch-specific certificate of analysis indicating high purity.
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Medchemexpress LLC Hy-078020 (compound III-4) | 2756222-90-7 | 98.9% | 515.09 g/mol | C32H35ClN2O2 | 10 MG
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This small-molecule compound is a selective, orally active antagonist of the histamine H1 receptor with reported in vitro potency (H1 IC50 = 24.12 nM). It is supplied for research use with defined purity and storage recommendations.
- Selective, orally active histamine H1 receptor antagonist (H1 IC50 = 24.12 nM).
- Demonstrates selectivity versus muscarinic receptor (mAChR3 IC50 > 10 μM).
- High purity (98.9%) as supplied.
- Available as 10 mg powder and 10 mM solution in DMSO (1 mL).
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months).
- Suitable for in vitro pharmacology and allergic disease research models.
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eMolecules Ambeed / 3-Chloro-5-hydroxybenzonitrile / 1g / 525157913 / A258067 / / 473923-97-6 / MFCD11226540 / 153.570 / C7H4ClNO
Ambeed / 3-Chloro-5-hydroxybenzonitrile / 1g / 525157913 / A258067 / / 473923-97-6 / MFCD11226540 / 153.570 / C7H4ClNO
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Medchemexpress LLC Tallimustine hydroch 1mg | 118438-45-2 | 1MG
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Tallimustine hydrochloride a distamycin-A derivative is an anticancer agent[1
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Medchemexpress LLC Saxagliptin hydrochloride | 709031-78-7 | MFCD22572334 | 99.7% | 351.87 g/mol | C18H26ClN3O2 | 10 MG
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Saxagliptin hydrochloride is the hydrochloride salt of saxagliptin, a potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor supplied as a high-purity solid for laboratory research.
- High purity suitable for research applications.
- Potent DPP-4 inhibitor for enzymatic and cellular assays.
- Supplied in small mg quantities for compound screening and early-stage studies.
- Well-characterized chemical identity (CAS: 709031-78-7).
- Molecular formula C18H26ClN3O2; molecular weight 351.87 g/mol.
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Medchemexpress LLC Levomedetomidine hydrochloride | 190000-46-5 | MFCD12912677 | 99.4% | 236.74 | C13H17ClN2 | 5 MG
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Levomedetomidine hydrochloride is the levorotatory enantiomer of medetomidine, described as a cardioprotective agent with sedative and analgesic effects. Supplied as a white to off-white solid for research use only, it is used in preclinical pharmacology and biochemical studies involving α2-adrenergic receptor activity.
- Enantiomer of medetomidine with levorotatory configuration.
- Cardioprotective agent with sedative and analgesic activity.
- High purity suitable for analytical and preclinical research.
- Solid, white to off-white physical form for easy handling.
- Supplied in small pack sizes appropriate for reference studies.
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Ambeed N1 2Methylnaphthalen1yl N2 pyr
N1-(2-Methylnaphthalen-1-yl)-N2-(pyridin-2-ylmethyl)oxalamide, 2611225-93-3, 98%
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