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Filtered Search Results
Selleck Chemical LLC CA-074 methyl ester
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CA-074 methyl ester (CA-074 Me Cathepsin B Inhibitor IV) is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor
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Chem-Impex International, Inc. 2-Oxo-2H-pyran-5-carboxylic acid methyl ester | MFCD00010120 | 5G
2-Oxo-2H-pyran-5-carboxylic acid methyl ester, MFCD00010120, 5G
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Chem-Impex International, Inc. 6-Quinolinecarboxylic acid methyl ester | MFCD00956766 | 1G
6-Quinolinecarboxylic acid methyl ester, MFCD00956766, 1G
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Medchemexpress LLC ZXH-1-161 | 2407654-51-5 | 98.4% | 468.51 | 5 MG
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ZXH-1-161 is a potent CRBN modulator that selectively induces the degradation of GSPT1 in a CRBN-dependent manner. It can inhibit the proliferation of multiple myeloma cells and exhibits antitumor activity.
- Potent CRBN modulator
- Selectively induces degradation of GSPT1
- Inhibits proliferation of multiple myeloma cells
- Exhibits antitumor activity
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Sigma Aldrich Fine Chemicals Biosciences Citronellyl isobutyrate >=92%, FCC | Purity: >=92% | Mol Wt: 226.36 | 97-89-2 | MFCD00026443 |
Citronellyl isobutyrate >=92%, FCC | 97-89-2 | MFCD00026443 |
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Cayman Chemical ANTIBODY CA-074 500ug
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A selective cathepsin B inhibitor (Kis = 0.0087, 75, and 233 μM for rat cathepsin B, H, and L, respectively); inhibits degradation of DQ-collagen IV and DQ-collagen I in 4T1.2 breast cancer cells; reduces the number of lung and bone metastases in a 4T1.2 murine mammary cancer model at 50 mg/kg; reduces mercury-induced increases in expression of TNF-α, IL-1β, and the inflammasome component NRLP3 and decreases the severity of mercury-induced skin induration in mice at 0.1 and 0.2 mg/kg; reduces ischemia-induced hippocampal neuron cell death in monkeys
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eMolecules 5398-79-8 | 2-(2,5-Dichlorophenyl)acetic acid | Ambeed | MFCD02664807 | 205.030 | C8H6Cl2O2 | 98.000 | OC(=O)Cc1cc(Cl)ccc1Cl | 250mg | 521432312
2-(2,5-Dichlorophenyl)acetic acid | Ambeed | 5398-79-8 | MFCD02664807 | 205.030 | C8H6Cl2O2 | 98.000 | OC(=O)Cc1cc(Cl)ccc1Cl | 250mg | 521432312
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Medchemexpress LLC Desoxycorticosterone pivalate | 808-48-0 | MFCD00199992 | 99.6% | 414.58 g/mol | C26H38O4 | 25 MG
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Desoxycorticosterone pivalate (DOCP) is a mineralocorticoid hormone analog used in pharmacological and biochemical research, commonly in studies of mineralocorticoid receptor activity and in canine hypoadrenocorticism models. It is supplied as a research-grade powder with established analytical characterization and typical solvent compatibility for laboratory formulations.
- High purity suitable for analytical and research use.
- Supplied as a powder for flexible formulation and dosing.
- Compatible with DMSO for preparation of stock solutions.
- Storage stability documented for powder and solution states.
- Analytical support available, including COA, H NMR, and LC-MS data.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Monomethylauristatin F hydrochloride | 1415246-68-2 | 768.42 | C39H66ClN5O8 | 50 MG
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MMAF hydrochloride (Monomethylauristatin F hydrochloride) is a potent tubulin polymerization inhibitor used as an antitumor agent and as the cytotoxic payload in antibody-drug conjugates (ADCs). It is supplied in small milligram-scale amounts for research and ADC development.
- Potent tubulin polymerization inhibitor.
- Used as a cytotoxic component in ADCs.
- CAS number 1415246-68-2.
- Molecular weight 768.42.
- Chemical formula C39H66ClN5O8.
- Supplied as a solid in milligram quantities for research use.
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eMolecules 10250-61-0 | 1,5-Dimethyl-1H-pyrazole-3-carboxylic acid methyl ester | Chem-Impex | MFCD06661312 | 154.169 | C7H10N2O2 | 99.000 | COC(=O)c1cc(C)n(C)n1 | 1g | 386899433
1,5-Dimethyl-1H-pyrazole-3-carboxylic acid methyl ester | Chem-Impex | 10250-61-0 | MFCD06661312 | 154.169 | C7H10N2O2 | 99.000 | COC(=O)c1cc(C)n(C)n1 | 1g | 386899433
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Medchemexpress LLC Z-WEHD-FMK | 210345-00-9 | 98.0% | 763.77 | 5 MG
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Z-WEHD-FMK is a potent, cell-permeable, and irreversible caspase-1/5 inhibitor. It also shows a robust inhibitory effect on cathepsin B activity (IC50=6 μM).
- Blocks C. trachomatis-induced cleavage of golgin-84 and increases GM130 expression in cells.
- Inhibits E. piscicida-induced ZF4 cell cytotoxicity and pyroptotic morphology.
- Inhibits cytotoxicity induced by cytosolic LPS delivery.
- Reduces IL-1β release in bone marrow-derived macrophages (BMDM) depending on metal ion concentration.
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![eMolecules 5-Norbornene-2,2-dimethanol | Combi-Blocks |154.209 | C9H14O2 | 95.000 | OCC1(CO)C[C@@H]2C[C@H]1C=C2 | 1g | 401042964](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502189765.JPG-250.jpg)
eMolecules 5-Norbornene-2,2-dimethanol | Combi-Blocks |154.209 | C9H14O2 | 95.000 | OCC1(CO)C[C@@H]2C[C@H]1C=C2 | 1g | 401042964
5-Norbornene-2,2-dimethanol | Combi-Blocks |154.209 | C9H14O2 | 95.000 | OCC1(CO)C[C@@H]2C[C@H]1C=C2 | 1g | 401042964
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![Medchemexpress LLC Methyl 5-[benzylsulfonyl-...]-2-[(4-methylphenyl)methoxy]benzoate | 1919853-46-5 | MFCD31382181 | 99.9% | 680.79 | C34H36N2O9S2 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000215068.png-250.jpg)
Medchemexpress LLC Methyl 5-[benzylsulfonyl-...]-2-[(4-methylphenyl)methoxy]benzoate | 1919853-46-5 | MFCD31382181 | 99.9% | 680.79 | C34H36N2O9S2 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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PTP1B-IN-2 is a potent small-molecule inhibitor of protein tyrosine phosphatase 1B (PTP1B) that potently inhibits the target (IC50 = 50 nM) and demonstrates cellular activity by enhancing insulin receptor β phosphorylation and increasing insulin-stimulated glucose uptake in muscle cells.
- Potent PTP1B inhibition (IC50 50 nM).
- High selectivity versus SHP-2 and LAR (>40-fold).
- Improved selectivity versus TCPTP (~15-fold).
- Enhances insulin-mediated IRβ phosphorylation in cells.
- Increases insulin-stimulated glucose uptake in L6 myotubes.
- High purity suitable for research use (≈99.9%).
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC CEFCAPENE PIVOXIL H 100 mg
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CEFCAPENE PIVOXIL H 100MG
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=O | 5g | 537664091](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502148529.JPG-250.jpg)
eMolecules 953-26-4 | Ethyl 4-nitrocinnamate | Oakwood Chemical | MFCD00007380 | 221.212 | C11H11NO4 | 98.000 | CCOC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O | 5g | 537664091
Ethyl 4-nitrocinnamate | Oakwood Chemical | 953-26-4 | MFCD00007380 | 221.212 | C11H11NO4 | 98.000 | CCOC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O | 5g | 537664091
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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