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Filtered Search Results
Chemscene CHEMSCENE
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5000580079 DIETHYL MALEATE 500G
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Cayman Chemical Thioperamide maleate
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A selective histamine H3 receptor antagonist that crosses the blood-brain barrier; binds to rat cerebral cortical cells in vitro with a pKi value of 8.4
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000289605 IMMH-010 MALEATE 10MG
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Apexbio Technology LLC CIPROXIFAN-MALEATE-5MG
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Ciproxifan maleate (CAS No 184025-19-2) is a potent histamine H3 receptor antagonist primarily studied in the field of neuropharmacology Originating from synthetic chemical research it functions by selectively blocking H3 receptors which modulate the release of histamine and other neurotransmitters in the brain influencing cognition and wakefulness In vitro studies show activity in the nanomolar to low micromolar range demonstrating its high affinity and specificity for the target receptor It is commonly used in cell models to explore neurological pathways and in animal studies to assess cognitive function and potential therapeutic effects for disorders such as narcolepsy and Alzheimer s disease Ciproxifan maleate is also utilized in drug screening contexts to identify compounds affecting histamine pathways Experimental concentrations typically depend on the specific research design allowing flexibility to accommodate diverse study parameters
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eMolecules 1438382-15-0 | 3-(Aminomethyl)-4-methoxy-6-methylpyridin-2-ol | MFCD29477778 | 250mg
Ambeed | 2-((S)-4-(4-Chlorophenyl)-239-trimethyl-6H-thieno[32-f][124]triazolo[43-a][14]diazepin-6-yl)-N-(8-(2-((2-(26-dioxopiperidin-3-yl)-13-dioxoisoindolin-4-yl)oxy)acetamido)octyl)acetamide | 1mg | 552735299 | A475199 | 1950634-92-0 | 841.380 | C42H45ClN8O7S
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000285040 TRIS MALEATE 25G
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Medchemexpress LLC Pirepemat fumarate (IRL752 fumarate) | 2251806-70-7 | >98.26% | 329.30 | 100 MG
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Pirepemat fumarate (IRL752 fumarate) is a cortical-preferring catecholamine- and cognition-promoting agent. It is utilized for the study of Parkinson's disease.
- Cortical-preferring catecholamine agent
- Cognition-promoting agent
- Used for the study of Parkinson's disease
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Apexbio Technology LLC CIPROXIFAN-MALEATE-10MG
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Ciproxifan maleate (CAS No 184025-19-2) is a potent histamine H3 receptor antagonist primarily studied in the field of neuropharmacology Originating from synthetic chemical research it functions by selectively blocking H3 receptors which modulate the release of histamine and other neurotransmitters in the brain influencing cognition and wakefulness In vitro studies show activity in the nanomolar to low micromolar range demonstrating its high affinity and specificity for the target receptor It is commonly used in cell models to explore neurological pathways and in animal studies to assess cognitive function and potential therapeutic effects for disorders such as narcolepsy and Alzheimer s disease Ciproxifan maleate is also utilized in drug screening contexts to identify compounds affecting histamine pathways Experimental concentrations typically depend on the specific research design allowing flexibility to accommodate diverse study parameters
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eMolecules 500788-85-2 | Boc-(R)-3-amino-3-(2-methoxyphenyl)propionic acid | Chem-Impex | MFCD02090692 | 295.335 | C15H21NO5 | 98.000 | COc1ccccc1C(CC(O)=O)NC(=O)OC(C)(C)C | 1g | 112747767
Boc-(R)-3-amino-3-(2-methoxyphenyl)propionic acid | Chem-Impex | 500788-85-2 | MFCD02090692 | 295.335 | C15H21NO5 | 98.000 | COc1ccccc1C(CC(O)=O)NC(=O)OC(C)(C)C | 1g | 112747767
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Medchemexpress LLC Pirepemat fumarate | 2251806-70-7 | 98.3% | 329.30 | 50 MG
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Pirepemat fumarate is a cortical-preferring catecholamine- and cognition-promoting agent. It is utilized in the study of Parkinson's disease and is intended for research use only.
- Highest in vitro affinities for 5-HT and NA-related targets.
- Reverses deficits resulting from hypomonoaminergic function in vivo.
- Induces dose-dependent and regio-selective alterations in brain monoamine transmission indices and gene expression.
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Medchemexpress LLC Mepyramine maleate (pyrilamine maleate) | 59-33-6 | 99.9% | 1 ML
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Mepyramine maleate is a first-generation antihistamine that acts as an antagonist of the histamine H1 receptor. It is characterized by specific binding affinities for H1, H2, and H3 receptors.
- Antagonist of the histamine H1 receptor
- Binds to H1 receptor with Kd of 0.8 nM
- Exhibits Kds of 5200 nM for H2 and >3000 nM for H3 receptors
- Decreases InsP levels in CHO-gpH1 cells
- Reduces maximal response to ATP in CHO-gpH1 cells
- Demonstrates analgesic effects in vivo at specific dosages
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Medchemexpress LLC Su14813 maleate | 849643-15-8 | MFCD24682713 | 99.0% | 558.56 g·mol⁻¹ | C27H31FN4O8 | 1 ML
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SU14813 maleate is a small-molecule, multi-targeted receptor tyrosine kinase inhibitor for research use. It potently inhibits VEGFR1, VEGFR2, PDGFRβ, and KIT in the low nanomolar range and is supplied as both a 10 mM solution in DMSO and as solid quantities for biochemical and cellular assays.
- Inhibits VEGFR1, VEGFR2, PDGFRβ, and KIT with low-nanomolar IC50s.
- Supplied as a 10 mM solution in DMSO and as solids for flexibility in experiments.
- High reported purity suitable for research applications.
- Molecular weight 558.56 g·mol⁻¹ and formula C27H31FN4O8 for reference.
- Available in small quantities for assay development and dose-response studies.
- Suitable for studying receptor tyrosine kinase signaling in vitro.
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Medchemexpress LLC Diethyl maleate | 141-05-9 | MFCD00009191 | 98.7% | 172.18 | C8H12O4 | 100mg
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Diethyl maleate (DEM) is an orally available effective glutathione (GSH) depletor that crosses the blood-brain barrier Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0 1-0 5 mM Diethyl maleate selectively depletes GSH in liver lung and brain tissues exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO- Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3]
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eMolecules Ambeed Benzyl propiolate 100mg 784395629 A332728 0 000 14447-01-9 MFCD11976128 160 172 C10H8O2
Ambeed Benzyl propiolate 100mg 784395629 A332728 0 000 14447-01-9 MFCD11976128 160 172 C10H8O2
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Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.8% | 391.42 | 5 MG
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Omigapil maleate (CGP3466B) is an orally active GAPDH nitrosylation inhibitor with potential for research into Alzheimer's disease and congenital muscular dystrophy (CMD). It is also an apoptosis inhibitor and a click chemistry reagent.
- Abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice
- Acts as an apoptosis inhibitor
- Can be used for research of congenital muscular dystrophy (CMD)
- Functions as a click chemistry reagent containing an Alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
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