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Filtered Search Results
Medchemexpress LLC Indacaterol maleate (standard) | 753498-25-8 | 99.6% | C28H32N2O7 | 100 MG
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Indacaterol maleate (standard) | 753498-25-8 | 99.6% | C28H32N2O7 | 100 MG
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Apexbio Technology LLC CA-074 Me 147859-80-1 5mg
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CA-074 Me (CAS 147859-80-1) is a cell-permeable methyl ester derivative of CA-074 functioning primarily as a selective inhibitor of cathepsin B It exhibits potent inhibitory activity against cathepsin B (IC50 36 3 nM) In cultured human gingival fibroblasts CA-074 Me effectively suppresses cathepsin B activity while moderately reducing combined cathepsin B and L activities Under strong reducing conditions (e g presence of DTT or GSH) CA-074 Me inhibits cathepsin L substantially Thus it is widely utilized in biomedical research to study lysosomal enzyme functions and roles of cathepsins in cellular processes
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Apexbio Technology LLC CA 074 134448-10-5 1mg
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CA 074 (CAS 134448-10-5) is a selective inhibitor of cathepsin B a cysteine protease involved in diverse pathological mechanisms By targeting cathepsin B CA 074 alleviates neurotoxicity induced by amyloid-activated microglia and inhibits proteolytic cascades associated with cell growth suppression and plasminogen activation Additionally CA 074 treatment modulates immune responses by shifting CD4 T cells from a Th2 to a Th1 phenotype reducing IgE and IgG1 levels In vivo studies indicate that CA 074 can attenuate TNF- -induced hepatic injury highlighting its relevance as a research tool in inflammation immunology and neurodegenerative disease investigations
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Medchemexpress LLC Ilginatinib maleate | 1354799-87-3 | 99.9% | 505.50 | 25 MG
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Ilginatinib maleate | 1354799-87-3 | 99.9% | 505.50 | 25 MG
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eMolecules EMOLECULES INC
5000471967 METHYL PROPIOLATE 25G
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Sigma Aldrich Fine Chemicals Biosciences Ethyl-trans-2-octenoate >=98%, FG | 7367-82-0 | MFCD00015287 |
Ethyl-trans-2-octenoate >=98%, FG | Purity: >=98% | Mol Wt: 170.25 | 7367-82-0 | MFCD00015287 |
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AdipoGen Naphtholfluorescein diacetate
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Chemical. CAS 77084-71-0. Formula C32H20O7. Molecular Weight 516.5. Naphthofluorescein-diacetate is a non-fluoresent compound that is hydrolyzed by esterases to the fluorescent compound Naphthofluorescein. Spectral data lambdaex 594 nm lambdaem 663 nm in 0.1 M Tris pH 9.0 esterase. The fluorescent naphthofluorescein has been shown to be an inhibitor of furin.
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eMolecules (3-Hydroxy-propyl)-isopropyl-carbamic acid tert-butyl ester | 873437-13-9 | MFCD12781066 | 5g
J & W PharmLab LLC | (3-Hydroxy-propyl)-isopropyl-carbamic acid tert-butyl ester | 5g | 289351005 | 20R0988 | 97.000 | 873437-13-9 | MFCD12781066 | 217.309 | C11H23NO3
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Medchemexpress LLC Monomethylauristatin F | 745017-94-1 | MFCD25976742 | >95.0% | 731.96 g/mol | C39H65N5O8 | 50 MG
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MMAF (Monomethylauristatin F) is a synthetic antimitotic agent that inhibits tubulin polymerization and is widely used as a cytotoxic payload in antibody-drug conjugates (ADCs) and for antitumor research. It is supplied for research use and should be handled under appropriate safety precautions.
- Potent tubulin polymerization inhibitor.
- Used as a cytotoxic payload in antibody-drug conjugates (ADCs).
- Cas number 745017-94-1.
- Molecular formula C39H65N5O8; molecular weight 731.96 g/mol.
- Typical storage: 4°C, sealed and protected from moisture.
- Common research pack size: 50 mg.
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Medchemexpress LLC SODIUM DIACETATE 500G
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5000205838 SODIUM DIACETATE 500G
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Medchemexpress LLC Sumanirole (maleate) | 179386-44-8 | 99.8% | C15H17N3O5 | 25 MG
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Sumanirole maleate (U-95666E; PNU-95666E) is a highly selective D2 receptor full agonist with an ED50 of about 46 nM. It plays an important role in the research of Parkinson's disease and restless leg syndrome. Sumanirole is a valuable tool compound for basic research to identify neurobiological mechanisms based on a dopamine D2-linked (vs. D1, D3, D4, and D5-linked) mechanism of action.
- Highly selective D2 receptor full agonist
- ED50 of about 46 nM
- Valuable tool for identifying neurobiological mechanisms
- Used in research for Parkinson's disease
- Used in research for restless leg syndrome
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Medchemexpress LLC Monostearyl maleate | 2424-62-6 | MFCD08274815 | 98.0% | 368.55 g·mol⁻1 | C22H40O4 | 250 MG
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Monostearyl maleate (octadecyl fumarate) is a long-chain alkyl ester supplied as a solid analytical reagent for biochemical and metabolic research. It is provided at high purity (≈98%) and is commonly used as an analytical standard or assay reagent in metabolism-related studies. Key identifiers include CAS 2424-62-6, molecular formula C22H40O4, and molecular weight 368.55 g·mol⁻1.
- High purity suitable for analytical use.
- Solid form for convenient handling and storage.
- Used in biochemical and metabolism assay workflows.
- Available in small pack sizes for analytical and standard applications.
- CAS-registered compound for unambiguous identification.
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![Medchemexpress LLC 6-[2-(2,4-difluorophenoxy)-5-(ethylsulfonylmethyl)-3-pyridinyl]-8-methyl-2H-pyrrolo[1,2-a]pyrazin-1-on | 2411226-02-1 | 99.9% | 459.47 g·mol⁻¹ | C22H19F2N3O4S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000262234.png-250.jpg)
Medchemexpress LLC 6-[2-(2,4-difluorophenoxy)-5-(ethylsulfonylmethyl)-3-pyridinyl]-8-methyl-2H-pyrrolo[1,2-a]pyrazin-1-on | 2411226-02-1 | 99.9% | 459.47 g·mol⁻¹ | C22H19F2N3O4S | 5 MG
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BET bromodomain inhibitor 1 is a selective, orally active inhibitor of bromodomain and extra-terminal (BET) proteins with potent activity against BRD4 (IC50 = 2.6 nM). Supplied as a white to off-white solid with high purity, it is used in epigenetic target validation and anticancer mechanism research.
- Potent BRD4 inhibition (IC50 2.6 nM).
- Low-nanomolar binding to BET family bromodomains.
- High purity suitable for research (99.9%).
- Soluble in DMSO at 100 mg/mL with warming and sonication.
- Stable when stored as a powder at -20°C for long-term storage.
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Medchemexpress LLC Neratinib (maleate) | 915942-22-2 | MFCD30607264 | 99.7% | 673.11 | C34H33ClN6O7 | 10 MG
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Neratinib maleate is the maleate salt of neratinib, an orally available, irreversible inhibitor selective for HER2 and EGFR kinases. Supplied for research use, it is used to probe HER2/EGFR signaling and to evaluate kinase inhibition in preclinical studies.
- Irreversible HER2 and EGFR inhibitor with IC50s of 59 nM (HER2) and 92 nM (EGFR).
- High purity (99.7%) suitable for analytical and biological assays.
- Molecular weight 673.11 and formula C34H33ClN6O7.
- Stable as a solid at 4°C; in solution: -80°C (6 months) or -20°C (1 month), protect from light.
- Available in small milligram pack sizes for research applications.
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Medchemexpress LLC HY-12466 1mg Medchemexpress, Z-DEVD-FMK CAS:210344-95-9 Purity:>98%
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Medchemexpress, HY-12466 1mg Z-DEVD-FMK CAS:210344-95-9 Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor with an IC50 of 18 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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