Carboxylic acid esters
TARGETMOL CHEMICALS INC FLUPIRTINE MALEATE 200MG
Also available in 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Flupirtine maleate (Katadolon maleate) a centrally acting non-opioid analgesia is the salt form of Flupirtine. It is an NMDA receptor antagonist and also a specific neuronal potassium channel opener. purity: 99%
Medchemexpress LLC Trimebutine maleate | 34140-59-5 | 99.7% | 1 G
Trimebutine maleate is a multi-target inhibitor and opioid receptor agonist with antimuscarinic activity. It inhibits L-type Ca2+ and large-conductance calcium-activated potassium channels, blocking ion influx and efflux. It also targets Toll-like receptors, suppressing signals and inhibiting LPS-induced IRAK1, ERK1/2, JNK, and NF-κB activation for anti-inflammatory effects. It induces tumor cell apoptosis via AKT/ERK pathway inhibition and prevents excessive smooth muscle contraction, making it useful for gastrointestinal disorder studies.
- Multi-target inhibitor and opioid receptor agonist
- Exhibits antimuscarinic activity
- Blocks calcium influx and potassium ion efflux
- Suppresses Toll-like receptor signals
- Provides anti-inflammatory effects
- Induces tumor cell apoptosis
- Inhibits excessive smooth muscle contraction
- Useful in gastrointestinal disorder research
Apexbio Technology LLC Flupirtine maleate 75507-68-5 100mg
Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
Apexbio Technology LLC Flupirtine maleate 75507-68-5 10mM (in 1mL DMSO)
Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
Apexbio Technology LLC Flupirtine maleate 75507-68-5 1g
Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
Medchemexpress LLC Flupirtine Maleate | 75507-68-5 | 100.0% | 420.39 | 100 MG
Flupirtine Maleate is an orally active, blood-brain barrier-crossing non-opioid analgesic and neuroprotective agent. It functions as a neuronal potassium channel opener (Kv7 activator), an NMDA receptor antagonist, and a GABA receptor activator. This agent is suitable for research related to focal cerebral ischemia, pain, Alzheimer's disease, or multiple sclerosis.
- Stabilizes blood-brain barrier integrity.
- Reduces oxidative stress and brain leukocyte infiltration.
- Enhances angioneurogenesis.
- Suppresses calcium influx.
- Stabilizes neuronal resting membrane potential.
- Counteracts focal cerebral ischemia.
- Exhibits analgesic and muscle relaxant properties.
- Protects neurons from excitotoxic, ischemic, or cytokine-mediated death.
Medchemexpress LLC Flupirtine (Maleate) | 75507-68-5 | 99.9% | 420.39 | 1 ML
Flupirtine Maleate is an orally active, blood-brain barrier-crossing non-opioid analgesic and neuroprotective agent. It exhibits analgesic and muscle relaxant properties, and protects neurons from excitotoxic, ischemic, or cytokine-mediated death.
- Neuronal potassium channel opener (Kv7 activator).
- NMDA receptor antagonist.
- GABA receptor activator.
- Stabilizes blood-brain-barrier integrity.
- Reduces oxidative stress and brain leukocyte infiltration.
- Enhances angioneurogenesis.
- Suppresses calcium influx.
- Stabilizes neuronal resting membrane potential.
- Counteracts focal cerebral ischemia.
- Functions as a non-opioid analgesic without antipyretic or antiphlogistic properties.
- Shows no relevant affinity to opiate receptor.
Medchemexpress LLC Flupirtine maleate | 75507-68-5 | 100.0% | 420.39 | 50 MG
Flupirtine Maleate is an orally active, blood-brain barrier-crossing non-opioid analgesic and neuroprotective agent. It functions as a neuronal potassium channel opener (Kv7 activator), an NMDA receptor antagonist, and a GABA receptor activator. It stabilizes blood-brain-barrier integrity and protects neurons.
- Stabilizes blood-brain-barrier integrity and reduces oxidative stress
- Enhances angioneurogenesis and suppresses calcium influx
- Stabilizes neuronal resting membrane potential
- Counteracts focal cerebral ischemia
- Exhibits analgesic and muscle relaxant properties
- Protects neurons from excitotoxic, ischemic, or cytokine-mediated death
- Functions as a non-opioid analgesic
- Used for research on focal cerebral ischemia, pain, Alzheimer's disease, or multiple sclerosis