Carboxylic acid salts
Apexbio Technology LLC Rigosertib sodium salt 1225497-78-8 100mg
Rigosertib sodium salt (CAS 1225497-78-8) is a selective inhibitor targeting Polo-like kinase 1 (PLK1) with reported IC50 approximately 9 nM The compound notably decreases proliferation of cancer cell lines demonstrating nanomolar IC50 values in HeLa (115 nM) and C33A (45 nM) cells whereas normal cells (e g BJ and Ect1/E6E7) remain largely unaffected At concentrations exceeding 0 5 M rigosertib robustly induces G2/M phase arrest in cancer cells without significant cell cycle disruption at lower doses Additionally in vivo studies suggest its potential as a radiosensitizer in cervical carcinoma research
Apexbio Technology LLC AVE 0991 sodium salt 306288-04-0 5mg
AVE 0991 sodium salt (CAS 306288-04-0) is a synthetic non-peptide agonist of the angiotensin-(1-7) receptor Mas Acting as a functional mimic of angiotensin-(1-7) AVE 0991 competitively binds to endothelial cell membranes with an IC50 of 21 35 nM in bovine aortic endothelial cells In vitro treatment with AVE 0991 promotes nitric oxide release to levels significantly greater than angiotensin-(1-7) In vivo AVE 0991 reduces urine volume and increases urine osmolality in mice effects reversed by angiotensin II antagonists indicating receptor specificity It also inhibits atherogenesis in ApoE knockout mice supporting its application in cardiovascular and renal research
Apexbio Technology LLC CX-4945 sodium salt 1309357-15-0 5mg
CX-4945 sodium salt (Silmitasertib sodium salt CAS 1309357-15-0) is a potent and selective inhibitor of casein kinase 2 (CK2) effectively targeting both the CK2 and CK2 catalytic subunits By inhibiting CK2 activity CX-4945 disrupts signaling pathways involved in cell cycle progression transcriptional regulation and cell survival The compound exhibits oral bioavailability and is widely utilized in research focused on tumor biology mechanistic studies of signaling cascades and the functional characterization of protein kinases
Apexbio Technology LLC Azlocillin sodium salt 37091-65-9 1g
Azlocillin sodium salt (CAS 37091-65-9) is a small-molecule inhibitor targeting penicillin-binding proteins (PBPs) It is designed to inhibit bacterial cell wall synthesis thereby impeding cross-linking of peptidoglycan layers and inducing bacterial lysis Azlocillin sodium salt exerts its biological activity primarily through inhibition of PBPs disrupting cell wall integrity in bacteria In microbiological assays azlocillin demonstrates broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria reported IC50 values vary by microbial species and experimental conditions typically determined in minimum inhibitory concentration (MIC) assays Based on these pharmacological properties azlocillin sodium salt holds research potential in microbiological and biomedical investigations including studies of bacterial susceptibility resistance mechanisms and combinational antimicrobial therapies
Apexbio Technology LLC Cefazolin (sodium salt) 27164-46-1 1g
Cefazolin sodium salt (CAS 27164-46-1) is a semisynthetic antibiotic that inhibits bacterial cell wall synthesis by binding to specific penicillin-binding proteins thereby blocking transpeptidation reactions essential for peptidoglycan formation In in vitro studies cefazolin sodium salt suppresses the proliferation of cultured osteoblast-like MG-63 cells exhibiting substantial cytotoxicity at concentrations of 10 000 g/ml precise IC50 values depend on cell type and experimental conditions Cefazolin sodium salt is commonly used in microbiology pharmacokinetic investigations and infection models particularly within studies of antimicrobial susceptibility and renal dysfunction
Sigma Organic Chemistry Diethyl oxalate | 25G | 95-92-1 | MFCD00009119
CAS #: 95-92-1
MDL #: MFCD00009119
Purity: >99 %
UNSPSC Code: 12352100
Molecular Weight: 146.14
Sigma Aldrich Fine Chemicals Biosciences Glycerol phosphate disodium salt hydrate isomeric mixture | 55073-41-1 | MFCD00149082 | 1KG
Glycerol phosphate disodium salt hydrate isomeric mixture | 55073-41-1 | MFCD00149082 | 1KG
Sigma Aldrich Fine Chemicals Biosciences Sodium succinate dibasic hexahydrate BioReagent, suitable for cell culture, suitable for insect cell culture | 6106-21-4 | MFCD00149117 | 100G
Sodium succinate dibasic hexahydrate BioReagent, suitable for cell culture, suitable for insect cell culture | Mol Wt: 270.14 | 6106-21-4 | MFCD00149117 | 100G
Sigma Aldrich Fine Chemicals Biosciences Etidronate disodium hydrate >=97% (NMR), solid | 7414-83-7 (anhydrous) | MFCD00152567 | 10MG
Etidronate disodium hydrate >=97% (NMR), solid | Purity: >=97% (NMR) | 7414-83-7 (anhydrous) | MFCD00152567 | 10MG
Sigma Aldrich Fine Chemicals Biosciences Methoxyacetonitrile >=98% | 1738-36-9 | MFCD00001892 | 5G
Methoxyacetonitrile >=98% | Purity: >=98% | Mol Wt: 71.08 | 1738-36-9 | MFCD00001892 | 5G
Sigma Aldrich Fine Chemicals Biosciences Sodium DL-lactate solution | 72-17-3 | MFCD00065400 | 1L
Sodium DL-lactate solution | Mol Wt: 112.06 | 72-17-3 | MFCD00065400 | 1L
Sigma Aldrich Fine Chemicals Biosciences Sodium gluconate meets USP testing specifications | 527-07-1 | MFCD00064210 | 100g
Sodium gluconate meets USP testing specificationsPurity: | MW: 218.14 | 527-07-1 | MFCD00064210 | 100g
Sigma Aldrich Fine Chemicals Biosciences Potassium D-gluconate | 299-27-4 | MFCD00064211 | 100g
Potassium D-gluconate | Purity: 99% | Mol Wt: 234.25 | 299-27-4 | MFCD00064211 | 100g
Sigma Aldrich Fine Chemicals Biosciences Cibenzoline succinate >=98% (HPLC), solid | 100678-32-8 | MFCD00941423 | 10MG
Cibenzoline succinate >=98% (HPLC), solid | Purity: >=98% (HPLC) | Mol Wt: 380.44 | 100678-32-8 | MFCD00941423 | 10MG
Sigma Aldrich Fine Chemicals Biosciences Anisyl formate | 122-91-8 | MFCD00021045 |
Anisyl formate | Purity: 90% | MW: 166.17 | 122-91-8 | MFCD00021045 | 0