Dicarboxylic acids and derivatives
Medchemexpress LLC RG-101 sodium | 00-00-0 | 95.4% | 8537.6 (free acid) | C295H410N78Na19O146P19S17 | 5 MG
RG-101 sodium is a hepatocyte-targeted N-acetylgalactosamine (GalNAc)-conjugated antisense oligonucleotide that antagonizes microRNA-122 (miR-122), a host factor important for hepatitis C virus replication. Supplied as a sodium salt, it is used in research to study miR-122 biology and antiviral mechanisms.
- Hepatocyte-targeted GalNAc conjugate for liver delivery.
- Antagonizes miR-122 to modulate hepatitis C virus-related pathways.
- High molecular weight oligonucleotide for sequence-specific activity.
- High purity (95.4%) suitable for research applications.
- Soluble in water; sonication may be required for dissolution.
- Recommended storage at -20°C; in solution store at -80°C for long-term.
Medchemexpress LLC AVN-101 hydrochlorid 5mg | 1061354-48-0 | 340.89 g/mol | C21H25ClN2 | 5 MG
AVN-101 hydrochloride is a brain-penetrant, orally active 5-HT7 receptor antagonist used in pharmacological research. Supplied as a 5 mg powder with high purity, it is suitable for in vitro assays and preclinical studies requiring selective serotonergic modulation.
- High purity suitable for research applications.
- Brain-penetrant profile for central nervous system studies.
- Orally active salt form compatible with dosing studies.
- Stable powder for sealed, low-temperature storage.
- Small packaging appropriate for early-stage research.
Medchemexpress LLC 7-((4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 50 MG
CUDC-101 is a small-molecule research inhibitor of histone deacetylases (HDACs), epidermal growth factor receptor (EGFR), and HER2, used in preclinical cancer research to assess antiproliferative and target-specific effects.
- Potent inhibitor of HDAC, EGFR, and HER2 with low-nanomolar activity.
- Demonstrates broad antiproliferative effects across cancer cell lines.
- Supplied as a light yellow to yellow powder for laboratory use.
- High purity suitable for research applications (reported ≥98% by HPLC).
- Available in small-mass packaging for research workflows.
- Molecular weight 434.49 g/mol.
Medchemexpress LLC PKUMDL-LC-101-D04 50mg | 2143896-83-5 | 378.94 g·mol⁻¹ | C14H23ClN4O2S2 | 50 MG
Small-molecule allosteric activator of glutathione peroxidase 4 (GPX4) used as a research tool to study ferroptosis and inflammation. Reported activity includes an approximate pEC50 of 4.7 and an ability to increase GPX4 activity in biochemical assays. Supplied as a solid with good solubility in DMSO for assay preparation.
- Allosteric activation of glutathione peroxidase 4 with reported pEC50 ≈ 4.7.
- Shown to increase GPX4 activity to about 150% in biochemical assays.
- Useful for probing ferroptosis and inflammation pathways in preclinical research.
- Supplied as a solid with high DMSO solubility for convenient dilution and assay use.
- Vendor-reported molecular formula and molecular weight provided for analytical reference.
Medchemexpress LLC PKUMDL-LC-101-D04 25mg | 2143896-83-5 | 378.9 | C14H22N4O2S2 • HCl | 25 MG
PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a small-molecule allosteric activator of glutathione peroxidase 4 (GPX4). It increases GPX4 enzymatic activity (pEC50 = 4.7) in biochemical and cell-based assays and has been reported to inhibit ferroptosis and inflammatory responses. The compound is supplied as the monohydrochloride salt with reported high purity and is intended for research use.
![Medchemexpress LLC 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247159.png-250.jpg)
Medchemexpress LLC 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide | 1012054-59-9 | MFCD15528940 | >98.0% | 434.49 g/mol | C24H26N4O4 | 100 MG
CUDC-101 is a small-molecule research compound that concurrently inhibits histone deacetylases (HDACs) and receptor tyrosine kinases EGFR and HER2. It is used in preclinical cancer research to study combined epigenetic and kinase-targeted therapies.
- Potent inhibition of HDAC, EGFR, and HER2 with IC50s of 4.4 nM, 2.4 nM, and 15.7 nM.
- Contains a hydroxamic acid moiety associated with HDAC activity.
- High purity (>98.0%) suitable for research applications.
- Soluble in DMSO at 25 mg/mL (approximately 57.54 mM; may require ultrasonic agitation).
- Molecular formula C24H26N4O4 and molecular weight 434.49 g/mol.
Medchemexpress LLC Lauroyl coenzyme A (lithium) | 190063-12-8 | 99% | 1 MG
Lauroyl coenzyme A lithium salt is an intermediary in fatty acid synthesis or metabolism. It is formed by combining long-chain fatty acids (specifically lauric acid) with coenzyme A. This compound plays a role in lipid biosynthesis and fatty acid transport, where coenzyme A acts as a transport molecule to facilitate the movement and targeting of specific compounds.
- Intermediary in fatty acid synthesis or metabolism.
- Formed by combining long-chain fatty acids (lauric acid) with coenzyme A.
- Involved in lipid biosynthesis and fatty acid transport.
- Coenzyme A acts as a transport molecule to help move and target specific compounds.
- Purity: 99%.
- Appearance: White to off-white solid.
Medchemexpress LLC Sodium lauroyl glutamate | 29923-31-7 | 95.8% | 100 MG
Sodium lauroyl glutamate is an anionic amino acid surfactant. It has the potential for irritant contact dermatitis and possible anti-irritating potential in a surfactant mixture on human skin. It is primarily used in cleaning products and has been shown to exhibit low irritation to nude mouse skin at 1% w/w for 1 hour. This product is for research use only and not sold to patients.
- Anionic amino acid surfactant.
- Low irritation to nude mouse skin at 1% w/w for 1 hour.
- Primarily used in cleaning products.
- Mild surfactant with a pH value of 5.41.
- For research use only.
Medchemexpress LLC Lauroyl-L-carnitine (chloride) | 6919-91-1 | 98.1% | 100 MG
Lauroyl-L-carnitine chloride is an orally active metabolite. It significantly reverses the decrease in its target gene IL-10 and alleviates Crohn's-like colitis. This compound exhibits anti-inflammatory effects and improves both systemic and local phenotypes in TNBS mice.
- Orally active metabolite
- Significantly reverses decrease in IL-10
- Alleviates Crohn's-like colitis
- Exhibits anti-inflammatory effects
- Improves systemic and local phenotypes in TNBS mice
- For research use only
Medchemexpress LLC Sodium lauroyl glutamate | 29923-31-7 | 95.8% | 1 G
Sodium lauroyl glutamate is an anionic amino acid surfactant used primarily in cleaning products. It is considered a mild surfactant with low irritation to nude mouse skin, exhibiting a pH value of 5.41. It also has potential for irritant contact dermatitis and possible anti-irritating effects in surfactant mixtures on human skin.
- Anionic amino acid surfactant
- Mild surfactant properties
- Ideal for cleaning product formulations
- Low irritation potential
- pH value of 5.41
TARGETMOL CHEMICALS INC AV-101 5MG
Also available in 1mg 10mg 25mg 50mg 100mg 500mg and bulk. Please contact Fisher for quotes. AV-101 (4-Cl-KYN) a prodrug antagonist at the glycine site of the NMDA receptor has antidepressant activity and reduces levodopa-induced dyskinesia in MPTP monkeys. purity: 98%
AdipoGen Sulforhodamine 101 acid Cl
Chemical. CAS 82354-19-6. Formula C31H29ClN2O6S2. MW 625.15. Synthetic. Sulforhodamine 101 sulfonyl chloride also called Texas Red sulfonyl chloride is a popular long wavelength amine-reactive rhodamine dye. Because the dye is quite unstable in water, reactions with amines in an aqueous solution must be carried out at low temperature over ice or at 4°C and usually at pH 8.5.
TARGETMOL CHEMICALS INC MG-101 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins. purity: 98%