Tricarboxylic acids and derivatives
Medchemexpress LLC Citrate synthase | 9027-96-7 | MFCD00131495 | ~98 KDa dimer | 250 U
Citrate synthase catalyzes the first reaction of the citric acid cycle, condensing acetyl-CoA and oxaloacetate to form citrate. This enzyme is localized within eukaryotic cells in the mitochondrial matrix.
- Catalyzes the first reaction of the citric acid cycle
- Condenses acetyl-CoA and oxaloacetate to form citrate
- Localized in the mitochondrial matrix
- Specific activity: ≥100 U/mg protein
- Appearance: Colorless to light yellow liquid
- Source: Microorganism
Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 50 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are composed of two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs utilize two ligands connected by a linker
- One ligand binds to an E3 ubiquitin ligase
- Other ligand binds to the target protein
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- High solubility in DMSO (100 mg/mL)
Medchemexpress LLC 3,6,11-Trioxa-9-azatridecanoic acid, 12,12-dimethyl-10-oxo- | 108466-89-3 | 263.29 | 25 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- Peg-based protac linker
- Used in the synthesis of protacs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Contains two different ligands connected by a linker
- Includes a ligand for an E3 ubiquitin ligase
- Includes a ligand for a target protein
Medchemexpress LLC diMal-O-CH2COOH | 1620837-47-9 | 96.8% | C13H12N2O7 | 50 MG
diMal-O-CH2COOH is a cleavable ADC linker.
- For research use only.
Medchemexpress LLC Amino-PEG3-CH2COOH | 134978-99-7 | 99.9% | C8H17NO5 | 1 G
Amino-PEG3-CH2COOH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting an E3 ubiquitin ligase ligand to a target protein ligand via a linker.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC 2'-deoxyuridine-5'-triphosphate trisodium salt | 102814-08-4 | MFCD00084701 | 99.7% | 534.09 | C9H12N2Na3O14P3 | 5 MG
dUTP trisodium (2'-deoxyuridine-5'-triphosphate trisodium salt) is the trisodium salt of dUTP, a deoxynucleotide triphosphate used as a dTTP substitute in PCR and related enzymatic applications to produce uracil-containing DNA. Supplied as a solid with high reported purity, it is intended for workflows that require uracil incorporation or UDG-based carryover prevention.
- High purity (99.74%) suitable for sensitive enzymatic reactions.
- Provided as a white to off-white solid, 5 mg pack size.
- Trisodium salt form for stable handling and solubility.
- Compatible with PCR and RT-PCR to produce uracil-containing PCR products.
- Supports uracil-DNA glycosylase (UDG)-based carryover prevention.
- Store sealed, away from moisture; in solution: -80°C (up to 6 months), -20°C (up to 1 month).
Selleck Chemical LLC Toremifene Citrate (NK 622) S1776-10mM/1mL
Toremifene Citrate (NK 622 NSC 613680) is an oral selective estrogen receptor modulator (SERM) used in the treatment of advanced breast cancer
Apexbio Technology LLC Tandospirone citrate 112457-95-1 5mg
Tandospirone citrate (CAS 112457-95-1) is a selective partial agonist of the 5-HT1A receptor exhibiting high affinity for this target (Ki 27 nM) while demonstrating markedly lower affinity for other receptors such as 5-HT2 5-HT1C 1 2 D1 and D2 (Ki 1300 41000 nM) In vitro tandospirone citrate shows the strongest binding to 5-HT1A receptors In vivo studies indicate it reduces premature responses in a dose-dependent manner suggesting an inhibitory effect on impulsive behavior Tandospirone citrate is utilized as a pharmacological tool in research on depression anxiety and other neuropsychiatric conditions
Medchemexpress LLC CH2COOH-PEG6-CH2COOH 250mg
CH2COOH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
![Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 1 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660960.jpg-250.jpg)
Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, [Citric Acid, Trisodium Dihydrate], 1 Kg
Sodium Citrate, Trisodium Salt, Dihydrate, laboratory grade, is commonly used in buffer preparation and other laboratory applications. This 1 kg package of trisodium citrate dihydrate is a versatile reagent that plays a critical role in maintaining pH balance during chemical and biological experiments. Sodium citrate is widely used in the preparation of anticoagulants for blood samples, in the formulation of buffers for molecular biology applications, and in various enzymatic assays. The trisodium salt form of citrate ensures effective buffering capabilities, maintaining stability across a broad range of pH values. This reagent is ideal for use in biochemical research and laboratory settings that require precise pH control.
Medchemexpress LLC Methadp triammonium (adenosine 5'-(α,β-methylene)diphosphate triammonium) | 99.9% | 476.32 | 100 MG
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor. It can be used for the research of ATP-adenosine pathway.
- Acts as a CD73 inhibitor
- Used for research of the ATP-adenosine pathway
- Inhibits 5'-AMP induced adenosine formation in A498 cells
Selleck Chemical LLC Edoxaban tosylate Monohydrate
Edoxaban (DU-176b) is a selective factor Xa inhibitor with Ki of 0 561 nM 10 000-fold selectivity over thrombin and FIXa and is also an orally bioavailable anticoagulant drug
Selleck Chemical LLC Sodium mesoxalate monohydrate S2992-100mg
Sodium mesoxalate monohydrate (sodium 2 2-dihydroxymalonate) is an endogenous metabolite
eMolecules 267221-90-9 | Tris(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amine | MFCD28098209 | 250mg
Ambeed | (R)-2-Hydroxypent-4-ene | 250mg | 553634464 | A915630 | 64584-92-5 | MFCD03701536 | 86.134 | C5H10O
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![Alkali Scientific 4 Methylumbelliferyl B D glucopyranoside Monohydrate [Methylumbelliferyl B D glucoside], 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660125.jpg-250.jpg)
Alkali Scientific 4 Methylumbelliferyl B D glucopyranoside Monohydrate [Methylumbelliferyl B D glucoside], 10 G
Methylumbelliferyl β-D Glucopyranoside Monohydrate, 10 g is a biochemical reagent used for the study of glucosidase enzyme activity. This substrate is hydrolyzed by glucosidases to release a fluorescent product, making it an essential tool for enzyme assays, diagnostic tests, and research into metabolic processes. The high purity and sensitivity of this reagent make it ideal for use in microbiology, clinical diagnostics, and genetic research, where detecting small quantities of enzyme activity is crucial. It is particularly useful in enzyme kinetics studies and applications requiring accurate and high-sensitivity measurements of glucosidase activity.