Tricarboxylic acids and derivatives
Medchemexpress LLC m-PEG8-CH2COOH | 102013-72-9 | 99.9% | 100 MG
m-PEG8-CH2COOH is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. These compounds operate by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based linker
- Used in the synthesis of PROTACs
- Selectively degrades target proteins
- Molecular weight: 442.50
- Formula: C19H38O11
- Appearance: Liquid
- Color: Colorless to light yellow
- Soluble in DMSO (200 mg/mL)
Medchemexpress LLC 5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester | 437655-96-4 | 99.4% | 1 G
Fmoc-NH-PEG6-CH2COOH is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It also functions as a PEG-based PROTAC linker, applicable in the synthesis of PROTACs. This compound facilitates the controlled degradation of target proteins by exploiting the intracellular ubiquitin-proteasome system.
- Cleavable linker for ADC synthesis
- PEG-based PROTAC linker
- Utilizes ubiquitin-proteasome system
- Enables selective degradation of target proteins
- Molecular weight of 561.62
- Formula C29H39NO10
- Appearance: colorless to light yellow liquid
- Soluble in DMSO (100 mg/mL)
Medchemexpress LLC Butamirate citrate | 18109-81-4 | MFCD00315222 | 99.9% | 499.6 g/mol | C24H37NO10 | 5 MG
Butamirate citrate is an orally active antitussive research compound supplied as the citrate salt. It acts centrally to suppress cough and has reported bronchodilatory and anti-inflammatory effects. Provided as a high-purity analytical standard for research use only.
- Orally active antitussive agent suitable for research.
- High purity analytical standard for assay and method development.
- Reported bronchodilatory and anti-inflammatory properties.
- Available in small packaged quantities for laboratory use.
- For research use only; not for human or clinical use.
Apexbio Technology LLC trans-Aconitic acid 4023-65-8 5g
trans-Aconitic acid (CAS 4023-65-8) is an unsaturated tricarboxylic acid endogenously detected in human urine It serves as a substrate for trans-aconitate 2-methyltransferase implicating it in metabolic pathways related to citrate metabolism Elevated urinary levels of trans-aconitic acid have been observed in conditions such as Reye s syndrome and certain organic acidurias suggesting its potential as a metabolic biomarker This compound is utilized in biomedical research to investigate metabolic dysregulation and to study enzyme-substrate interactions within organic acid metabolism
Medchemexpress LLC Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]- | 882518-90-3 | 99.0% | 189.17 | 100 MG
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Functions as a click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Chem-Impex International, Inc. Tris-(carboxyethyl)phosphine hydrochloride | 51805-45-9 | MFCD00145469 | 1G
Tris-(carboxyethyl)phosphine hydrochloride , 51805-45-9, MFCD00145469, 1G
Medchemexpress LLC Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]- | 882518-90-3 | 99.0% | 189.17 | 1 MG
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Can be used in the synthesis of PROTACs
- PROTACs utilize the intracellular ubiquitin-proteasome system to degrade target proteins
Medchemexpress LLC Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]- | 882518-90-3 | 99.03% | 189.17 | 10 MG
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Can be used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Azide group enables copper-catalyzed azide-alkyne cycloaddition.
- Can undergo strain-promoted alkyne-azide cycloaddition with DBCO or BCN groups.
Medchemexpress LLC Azido-PEG2-CH2COOH | 882518-90-3 | 99.03% | 189.17 | 1 ML
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs use the intracellular ubiquitin-proteasome system to degrade target proteins.
- PEG-based PROTAC linker.
- Click chemistry reagent.
- Contains an Azide group for CuAAc reaction with Alkyne groups.
- Can undergo SPAAC reactions with DBCO or BCN groups.
![eMolecules 546-46-3 | Zinc citrate dihydrate | Combi-Blocks, Inc.610.370 | C12H14O16Zn3 | 97.000 | O.O.[Zn++].[Zn++].[Zn++].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 5g | 603131897](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502189468.JPG-250.jpg)
eMolecules 546-46-3 | Zinc citrate dihydrate | Combi-Blocks, Inc.610.370 | C12H14O16Zn3 | 97.000 | O.O.[Zn++].[Zn++].[Zn++].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 5g | 603131897
Zinc citrate dihydrate | Combi-Blocks, Inc. | 546-46-3610.370 | C12H14O16Zn3 | 97.000 | O.O.[Zn++].[Zn++].[Zn++].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 5g | 603131897
Apexbio Technology LLC Citrate-Synthase-Act-Assay-Kit
Citrate Synthase Activity Assay Kit is a crucial tool in biochemical and pharmaceutical research primarily used to measure the enzymatic activity of citrate synthase an essential enzyme in the citric acid cycle Originating from cellular metabolism studies it aids in understanding the conversion of oxaloacetate and acetyl-CoA to citrate and CoA-SH This reaction plays a pivotal role in energy production and metabolic regulation The kit is commonly used in in vitro assays with activity detectable in nanomolar to low micromolar ranges Applications include use in cellular models animal studies and drug screening to analyze metabolic pathways and potential drug interactions Experimental concentrations typically depend on the specific research design Its precision and reliability make it indispensable for academics and industry professionals investigating metabolic disorders cancer metabolism and mitochondrial function