Tricarboxylic acids and derivatives
Chem-Impex International, Inc. Sodium citrate dihydrate | 6132-04-3 | MFCD00150031 | 2.5KG
Sodium citrate dihydrate, 6132-04-3, MFCD00150031, 2.5KG
Medchemexpress LLC Diphosphoric acid, mono[(2E)-4-hydroxy-3-methyl-2-butenyl] ester, triammonium salt | 443892-56-6 | 90.0% | C5H21N3O8P2 | 500 UG
HDMAPP triammonium is a potent phosphoantigen in the ammonium and pyrophosphate form of (E)-HDMAPP. It is an activator of γδ T cells and can induce T cell stimulation in vitro with an EC₅₀ of 0.39 nM for TNF-α release.
- Potent phosphoantigen
- Activates γδ T cells
- Induces T cell stimulation in vitro
- Increases TNF-α release in human Vγ9Vδ2 T cells
- Significantly increases γδ cells in cynomolgus monkey model
- White to off-white solid appearance
Selleck Chemical LLC Citric acid trilithium salt tetrahydrate S4519-100mg
Citric acid trilithium salt tetrahydrate (Trilithium citrate tetrahydrate Lithium citrate tribasic tetrahydrate) is a pharmaceutical and construction material It is commonly used in HPLC gradient elution for quantification of amino acids
Medchemexpress LLC Tos-PEG3-CH2COOH | 1581248-63-6 | 250 MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Contains two different ligands connected by a linker
- Suitable for cancer targeted therapy research
N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F | 25g | 624127118](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502171601.JPG-250.jpg)
eMolecules 654671-77-9 | SITAGPLIPTIN PHOSPHATE MONOHYDRATE | AstaTech | MFCD10001393 | 523.329 | C16H20F6N5O6P | 99.000 | O.OP(O)(O)=O.N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F | 25g | 624127118
SITAGPLIPTIN PHOSPHATE MONOHYDRATE | AstaTech | 654671-77-9 | MFCD10001393 | 523.329 | C16H20F6N5O6P | 99.000 | O.OP(O)(O)=O.N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F | 25g | 624127118
Medchemexpress LLC DMAPP (triammonium) | 1186-30-7 | 95.0% | 1 MG
DMAPP (Dimethylallyl diphosphate) triammonium is an isoprenoid precursor found in virtually all life forms. It is an isomer of isopentenyl pyrophosphate (IPP) and plays a role in both the mevalonate and MEP pathways of isoprenoid precursor biosynthesis. The enzyme isopentenyl pyrophosphate isomerase catalyzes the isomerization between DMAPP and IPP.
- Isoprenoid precursor
- Isomer of isopentenyl pyrophosphate (IPP)
- Found in virtually all life forms
- Product of mevalonate and MEP pathways
- Involved in isoprenoid precursor biosynthesis
- Isomerization catalyzed by isopentenyl pyrophosphate isomerase
Alkali Scientific L (+) Rhamnose, Monohydrate, 500 G
L (+) Rhamnose Monohydrate is a high-purity sugar used in laboratory applications, especially in studies of bacterial metabolism and plant biology. This 500-gram supply is ideal for experiments requiring a consistent and reliable source of rhamnose. It is commonly used in biochemical assays, microbiological testing, and as a substrate in fermentation processes. The monohydrate form ensures accurate and reproducible results in laboratory experiments. Rhamnose is used in research on plant cell wall metabolism, microbial growth studies, and other applications where precise sugar control is critical. This bulk quantity is perfect for continuous research and experimental work.
Medchemexpress LLC 2-methylcitric acid trisodium | 117041-96-0 | MFCD16875437 | 96.0% | 272.10 g·mol⁻1 | C7H7Na3O7 | 5 MG
2-Methylcitric acid trisodium is the trisodium salt of 2-methylcitric acid provided as a white to off-white solid for laboratory research. It is an endogenous metabolite used as a marker in methylmalonic and propionic acidemias and is employed in biochemical and mitochondrial studies, where it has been reported to inhibit ADP-stimulated mitochondrial respiration supported by glutamate.
- Trisodium salt, white to off-white solid.
- CAS number 117041-96-0.
- Purity 96.0%.
- Molecular weight 272.10 g·mol⁻1; formula C7H7Na3O7.
- Highly soluble in water (100 mg/mL; may require ultrasonication).
- Storage: sealed at 4°C; in solvent -80°C (6 months), -20°C (1 month).
- For research use only; not for human or veterinary use.
Medchemexpress LLC cGAMP diammonium | 96.6% | 708.47 | 50 MG
cGAMP (Cyclic GMP-AMP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. It activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators.
- Endogenous second messenger in metazoans.
- Triggers interferon production in response to cytosolic DNA.
- Activates stimulator of interferon genes (STING).
- Activates a signaling cascade leading to the production of type I interferons and other immune mediators.
- Promotes the antigen-specific proliferation capacity of spleen cells in mice.
- Directly activates murine and human dendritic cells *in vitro*.
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | >=97.0% | 100 MG
Bromo-PEG1-CH2COOH is a PROTAC linker, designed for use in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, by connecting an E3 ubiquitin ligase ligand to a target protein ligand.
- Used as a PROTAC linker
- Designed for PROTAC synthesis
- Contains two ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets a protein
- Exploits the ubiquitin-proteasome system
- Enables selective degradation of target proteins
- For research use only
Medchemexpress LLC 3-Thiophenecarboxylic acid, 2-[(4-chlorobenzoyl)amino]-4-ethyl-5-methyl-, methyl ester | 544450-68-2 | 99.94% | 337.82 | 100 MG
COR659 is a potent and effective GABAB positive allosteric modulator (PAM) that suppresses alcohol and chocolate self-administration in rats. Its effects are exerted through a composite mechanism, involving positive allosteric modulation of the GABAB receptor and an action at the cannabinoid CB1 receptor.
- Potent and effective GABAB positive allosteric modulator (PAM).
- Suppresses alcohol and chocolate self-administration in rats.
- Exerts effects through a composite mechanism.
- Involves positive allosteric modulation of the GABAB receptor.
- Acts at the cannabinoid CB1 receptor.
- Has shown cytotoxicity against mouse NIH/3T3 cells with an IC50 of 59 μM.
- Relevant to research in neurological, eye or ear disease, neurodegenerative disease, depression, Alzheimer's disease, and Parkinson's disease.
Medchemexpress LLC Tamoxifen (Citrate) | 54965-24-1 | 99.9% | 563.64 | 1 ML
Tamoxifen Citrate is an orally active, selective estrogen receptor modulator (SERM) that blocks estrogen action in breast cells while activating estrogen activity in other cells like bone, liver, and uterine cells. It functions as a potent Hsp90 activator, enhancing its molecular chaperone ATPase activity. Additionally, it can inhibit infectious EBOV Zaire and Marburg (MARV).
- Selective estrogen receptor modulator
- Blocks estrogen action in breast cells
- Activates estrogen activity in bone, liver, and uterine cells
- Potent Hsp90 activator
- Enhances Hsp90 molecular chaperone ATPase activity
- Inhibits infectious EBOV Zaire and Marburg (MARV)
- Activates autophagy
- Induces apoptosis
- Used to induce gene knockout in CreER transgenic mice
Medchemexpress LLC m-PEG8-CH2COOH | 102013-72-9 | 99.9% | 5 G
m-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It has a molecular weight of 442.50 and a chemical formula of C19H38O11. This compound appears as a colorless to light yellow liquid with a density of 1.122 g/cm3. For in vitro solubility, it dissolves in DMSO at 200 mg/mL.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Molecular weight: 442.50
- Formula: C19H38O11
- Appearance: liquid
- Color: colorless to light yellow
- In vitro solubility: 200 mg/mL in DMSO
- Pure form storage: stable for 3 years at -20°C or 2 years at 4°C
- In solvent storage: stable for 6 months at -80°C or 1 month at -20°C
Medchemexpress LLC Cyclic GMP-AMP diammonium | 96.6% | 708.47 g/mol | C20H30N12O13P2 | 5 MG
cGAMP diammonium is a cyclic dinucleotide that functions as an endogenous second messenger and a potent activator of the stimulator of interferon genes (STING) pathway. Provided as the diammonium salt for research use, it induces type I interferon production and is used to study innate immune signaling.
- Activates STING and triggers type I interferon signaling.
- High purity (96.6%) suitable for research applications.
- Molecular formula C20H30N12O13P2; molecular weight 708.47 g/mol.
- Water-soluble; dissolves up to 100 mg/mL with ultrasonic assistance.
- Solid storage recommended at -20°C; solution storage guidance provided.
- Supplied in small quantities (e.g., 5 mg) for laboratory use.
eMolecules 123-04-6 | 3-(Chloromethyl)heptane | Ambeed | MFCD00018940 | 148.670 | C8H17Cl | 98.000 | CCCCC(CC)CCl | 25g | 599120951
3-(Chloromethyl)heptane | Ambeed | 123-04-6 | MFCD00018940 | 148.670 | C8H17Cl | 98.000 | CCCCC(CC)CCl | 25g | 599120951