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Filtered Search Results
Ambeed AMBEED
5000869406 NN-DIMETHYLAZETIDIN-3-AMIN 1GR
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Aobchem AOBCHEM
5000862840 1- 2 3-DIHYDROBENZOFURAN-5-YL
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Medchemexpress LLC (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone | 141645-16-1 | 99.6% | C19H17NO5 | 50 G
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This chemical is a drug intermediate utilized in the synthesis of various active compounds. It is intended for research purposes only and not for patient use.
- Drug intermediate
- Solid appearance
- Off-white to yellow color
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Matrix Scientific METHYL 2-AMINOTHIAZOLE-4-CA-5G
Methyl 2-aminothiazole-4-carboxylate, 95%-5g,C5H6N2O2S, MFCD00622441, mw 158.18,
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Aobchem AOBCHEM
5000874033 2 6-DIMETHOXYPYRIDIN-3-YL PH
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000734150 1 2-DIPYRIDIN-4-YL 5G
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![Medchemexpress LLC N-butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)-benzamide | 2244678-29-1 | 98.4% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000234775.png-250.jpg)
Medchemexpress LLC N-butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)-benzamide | 2244678-29-1 | 98.4% | 1 ML
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TH-257 is a potent, selective allosteric inhibitor of LIM kinase 1 and LIM kinase 2 used as a chemical probe in cell biology research. It is supplied as a 10 mM solution in DMSO (1 mL vial), with typical purity of 98.36% and a molecular weight of 422.54 g/mol.
- Potent inhibition of LIMK1 and LIMK2 (IC50 84 nM and 39 nM).
- Allosteric mode of action with high selectivity against the kinome.
- Provided as a ready-to-use 10 mM solution in DMSO for in vitro studies.
- High purity suitable for research applications.
- Molecular formula C24H26N2O3S and molecular weight 422.54 g/mol.
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eMolecules 37159-60-7 | 3-BROMO-5-CHLORO-1,2,4-THIADIAZOLE | AstaTech | MFCD00799287 | 199.450 | C2BrClN2S | 95.000 | Clc1nc(Br)ns1 | 1g | 402181130
3-BROMO-5-CHLORO-1,2,4-THIADIAZOLE | AstaTech | 37159-60-7 | MFCD00799287 | 199.450 | C2BrClN2S | 95.000 | Clc1nc(Br)ns1 | 1g | 402181130
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Aobchem AOBCHEM
5000874050 1- 2 5-DIFLUOROPHENYL -2 2-DIF
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Medchemexpress LLC MET kinase-IN-4 | 888719-03-7 | 99.0% | 458.42 | 25 MG
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MET kinase-IN-4 is an orally active Met kinase inhibitor with potent Met kinase inhibitory activity (IC50 value of 1.9 nM). It can be used for cancer research. It also inhibits Flt-3 and VEGFR-2 kinases with IC50 values of 4 nM and 27 nM, respectively. MET kinase-IN-4 (3 μM) shows good metabolic stability in both human and mouse liver microsomes.
- Orally active Met kinase inhibitor.
- Potent Met kinase inhibitory activity with an IC50 value of 1.9 nM.
- Inhibits Flt-3 and VEGFR-2 kinases with IC50 values of 4 nM and 27 nM, respectively.
- Shows good metabolic stability in both human and mouse liver microsomes.
- Possesses a favorable pharmacokinetic profile in mice.
- Demonstrates significant in vivo antitumor activity in the GTL-16 human gastric carcinoma xenograft model.
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eMolecules AstaTech / 4-BROMO-5-NITROTHIAZOLE / 0.25g / 402180881 / 92247 / 95.000 / 1522380-26-2 / MFCD30530743 / 209.020 / C3HBrN2O2S
AstaTech / 4-BROMO-5-NITROTHIAZOLE / 0.25g / 402180881 / 92247 / 95.000 / 1522380-26-2 / MFCD30530743 / 209.020 / C3HBrN2O2S
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ACROTEIN CHEMBIO INC
NC3902637 N-FMOC-N-METHYL-/S\-2-AMIN-25G
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Medchemexpress LLC N-hydroxyhydantoin carbamate | 2331255-53-7 | 98.5% | 100 MG
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ABC99 is an N-hydroxyhydantoin carbamate small-molecule inhibitor of the Wnt-deacylating enzyme NOTUM (reported IC50 = 13 nM). It preserves Wnt3A signaling in cell-based assays and is supplied as a powder with recommended cold storage.
- Selective NOTUM inhibitor (IC50 = 13 nM).
- N-hydroxyhydantoin carbamate scaffold.
- Molecular formula C22H21ClN4O5.
- Molecular weight 456.88.
- Powder form; store powder at -20°C (3 years) or 4°C (2 years).
- Soluble in DMSO: 25 mg/mL (≈54.7 mM) with heating and sonication.
- Preserves Wnt3A signaling in cell-based assays.
- Available as a 100 mg research quantity.
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Medchemexpress LLC AGI-5198 (IDH-C35) | 1355326-35-0 | 99.9% | 462.56 | 1 G
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AGI-5198 (IDH-C35) is a potent and selective mutant IDH1R132H inhibitor, with an IC50 of 0.07 μM. It is for research use only and demonstrates dose-dependent inhibition of the mutant IDH1 enzyme in TS603 glioma cells. AGI-5198 can also reverse the effects of increased reactive oxygen species, DNA double-strand breaks, and cell death in IDH1(R132H) mutated cancer cells after exposure to ionizing radiation. In vivo studies show it causes 50 to 60% growth inhibition of human glioma xenografts.
- Solid appearance with a white to off-white color
- Inhibits IDH1R132H mutant with an IC50 of 0.07 μM
- Soluble in DMF and DMSO for in vitro applications
- Available in powder and solvent forms for varied storage conditions
- Demonstrates significant growth inhibition in human glioma xenografts
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Medchemexpress LLC N-benzyl-N-butyl-4-(phenylsulfamoyl)benzamide | 2244678-29-1 | 98.4% | 50 MG
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TH-257 (CAS 2244678-29-1) is a small-molecule allosteric inhibitor of LIM kinase 1 and 2 used as a biochemical research probe to study LIMK-mediated signaling pathways in vitro.
- Potent inhibitor of LIMK1 and LIMK2 with IC50 values of 84 nM and 39 nM.
- Molecular formula C24H26N2O3S and molecular weight 422.54 g/mol.
- High purity (98.36%) suitable for in vitro biochemical studies.
- Supplied as a solid powder and as a 10 mM solution in DMSO; common pack sizes include 5 mg, 10 mg, 50 mg, and 100 mg.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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