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Filtered Search Results
Medchemexpress LLC Phospho-Met (c-Met) (Tyr1349) Antibody (YA213) | 10 UL
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Phospho-Met c-Met (Tyr1349) Antibody (YA213) is a rabbit-derived, non-conjugated IgG monoclonal antibody specifically targeting Phospho-Met c-Met at the Tyr1349 residue. This antibody is supplied as a liquid in a formulation containing 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.05% BSA, and 0.01% Sodium azide as a preservative. It is suitable for various applications including Western Blot (WB) and Immunoprecipitation (IP).
- Specific for Phospho-Met c-Met (Tyr1349)
- Rabbit-derived IgG monoclonal antibody
- Non-conjugated for flexible experimental design
- Suitable for Western Blot (WB) and Immunoprecipitation (IP) applications
- Shipped with blue ice to maintain stability
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eMolecules 133311-51-0 | Ambeed | 2-Bromo-5-phenylthiazole | 100mg | 758385825 | A813345 | MFCD11109488 | 240.12 | C9H6BrNS
Ambeed | 1357-Tetraphenyladamantane | 5g | 591800469 | A321985 | 16004-75-4 | 440.630 | C34H32
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BIOHIPPO AAV-TH-fDIO-eNpHR3.0-mCherry-WPRE-hGH-polyA
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Recombinant adeno associated virus expressing eNpHR3.0 fused to mCherry under the TH promoter with WPRE and hGH polyA elements. The Cre and Flp logic configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Apexbio Technology LLC MTT Cell Proliferation Assay Kit 500T
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MTT Cell Proliferation Assay Kit is a colorimetric assay designed to quantify cell viability proliferation or cytotoxicity in mammalian cell cultures by measuring metabolic activity The kit exerts its biological activity through the enzymatic reduction of the tetrazolium dye MTT by actively respiring mitochondria in viable cells leading to the formation of insoluble purple formazan crystals The amount of formazan produced correlates with cellular metabolic activity Based on these properties MTT Cell Proliferation Assay Kit holds research potential in pharmaceutical screening toxicity testing oncology and cell biology research
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Medchemexpress LLC S2-16 | 672333-56-1 | 97.4% | 2973.36 | 1 MG
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S2-16 is a synthetic peptide derived from the S2 region of cardiac myosin. It functions as a cryptic epitope, capable of inducing myocarditis in Lewis rats. A cryptic epitope is defined as an epitope that remains unrecognized by antibodies or T cells after an animal has been immunized with the intact antigen. This characteristic makes S2-16 a valuable tool for investigating the underlying mechanisms of autoimmune myocarditis.
- Synthetic peptide from the S2 region of cardiac myosin.
- Induces myocarditis in Lewis rats.
- A cryptic epitope, meaning it is not recognized by antibodies or T cells after immunization with the intact antigen.
- Useful for studying the mechanism of autoimmune myocarditis.
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Medchemexpress LLC Met kinase-IN-2 | 2101241-90-9 | 98.4% | 562.59 g/mol | C33H27FN4O4 | 5 MG
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MET kinase-IN-2 is a potent, selective MET (c-Met/HGFR) kinase inhibitor with an enzymatic IC50 of 7.4 nM. The compound shows cellular growth inhibition across multiple cancer cell lines and demonstrates oral antitumor efficacy in xenograft models. It is supplied for preclinical research and is well characterized for purity and molecular properties.
- Potent MET kinase inhibition (IC50 7.4 nM).
- Selective profile with additional activity against AXL, Flt4, KDR, Mer, TEK, and TYRO3.
- Orally bioavailable with demonstrated in vivo antitumor efficacy.
- Documented cellular activity in multiple cancer cell lines.
- High purity and characterized molecular weight and formula.
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eMolecules 57159-62-3 | 2,5-dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate | Abosyn Chemicals Inc. | MFCD01863457 | 307.100 | C9H11BrN2O5 | 0.000 | BrCC(=O)NCCC(=O)ON1C(=O)CCC1=O | 1g | 476137987
2,5-dioxopyrrolidin-1-yl 3-(2-bromoacetamido)propanoate | Abosyn Chemicals Inc. | 57159-62-3 | MFCD01863457 | 307.100 | C9H11BrN2O5 | 0.000 | BrCC(=O)NCCC(=O)ON1C(=O)CCC1=O | 1g | 476137987
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eMolecules 78269-85-9 | Teoc-OSu | Ambeed | MFCD02683467 | 259.333 | C10H17NO5Si | 97.000 | C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O | 100g | 525085970
Teoc-OSu | Ambeed | 78269-85-9 | MFCD02683467 | 259.333 | C10H17NO5Si | 97.000 | C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O | 100g | 525085970
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eMolecules 78269-85-9 | 2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)ethyl) carbonate | Oakwood Chemicals | MFCD02683467 | 259.333 | C10H17NO5Si | 96.000 | C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O | 1g | 480163328
2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)ethyl) carbonate | Oakwood Chemicals | 78269-85-9 | MFCD02683467 | 259.333 | C10H17NO5Si | 96.000 | C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O | 1g | 480163328
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Medchemexpress LLC Cis VH-298 | 2097381-86-5 | 100.0% | 523.65 g/mol | C27H33N5O4S | 10 MG
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cis VH-298 is the cis stereoisomer of VH-298 that acts as a VHL:HIF-α interaction inhibitor. Compared with the trans isomer, the cis form shows a significant loss of binding specificity of hydroxylated HIF-1α peptides to the VHL protein in vitro. The compound is supplied as a white to off-white solid with high purity for research use and should be stored protected from light.
- Cis stereochemistry reduces binding specificity to VHL.
- Useful as a comparator in VHL-HIF biological studies.
- High purity (approximately 99.96%) suitable for biochemical assays.
- Molecular weight 523.65 g/mol; formula C27H33N5O4S.
- Solid, white to off-white appearance; store protected from light.
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eMolecules 848472-61-7 | 4-(BOC-AMINO)-2-METHYLTHIAZOLE | AstaTech | MFCD27923451 | 214.280 | C9H14N2O2S | 95.000 | Cc1nc(NC(=O)OC(C)(C)C)cs1 | 0.25g | 528975173
4-(BOC-AMINO)-2-METHYLTHIAZOLE | AstaTech | 848472-61-7 | MFCD27923451 | 214.280 | C9H14N2O2S | 95.000 | Cc1nc(NC(=O)OC(C)(C)C)cs1 | 0.25g | 528975173
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eMolecules 848472-61-7 | 4-(BOC-AMINO)-2-METHYLTHIAZOLE | AstaTech | MFCD27923451 | 214.280 | C9H14N2O2S | 95.000 | Cc1nc(NC(=O)OC(C)(C)C)cs1 | 1g | 528975174
4-(BOC-AMINO)-2-METHYLTHIAZOLE | AstaTech | 848472-61-7 | MFCD27923451 | 214.280 | C9H14N2O2S | 95.000 | Cc1nc(NC(=O)OC(C)(C)C)cs1 | 1g | 528975174
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eMolecules 1606-76-4 | Ambeed | 2-Nitrothiazole | 250mg | 758385805 | A789939 | MFCD01760316 | 130.12 | C3H2N2O2S
AstaTech | 2-AMINO-4-HYDROXY-PTERIDINE | 0.25g | 206678746 | 52716 | 95.000 | 2236-60-4 | MFCD01456481 | 163.140 | C6H5N5O
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Medchemexpress LLC (E)-5-fluoro-N-(3-(3-(hydroxyamino)-3-oxoprop-1-en-1-yl)-4-methoxybenzyl)-2-morpholinoben | 3031349-25-1 | 95.0% | 429.44 | 25 MG
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This potent HDAC inhibitor demonstrates IC50s for HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, and inhibits cell migration and invasion. It induces apoptosis and cell cycle arrest at the G2/M phase, also showing anti-tumor activity.
- Potent inhibition of HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8.
- Inhibits cell migration and invasion, and induces apoptosis and cell cycle arrest at G2/M phase.
- Demonstrates anti-tumor activity.
- Inhibits tubulin polymerization.
- Increases expression of acetylated-α-tubulin and acetyl-histone H3.
- Modulates mitochondrial membrane potential and reactive oxygen species levels.
- Exhibits favorable liver microsomal stability.
- Shows antiproliferative activities in various cancer cell lines.
- Demonstrates antivascular activity and good cardiovascular safety in vivo.
- Reduces tumor weights in allograft mouse models.
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Medchemexpress LLC N-butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)-benzamide | 2244678-29-1 | 98.4% | 1 ML
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TH-257 is a potent, selective allosteric inhibitor of LIM kinase 1 and LIM kinase 2 used as a chemical probe in cell biology research. It is supplied as a 10 mM solution in DMSO (1 mL vial), with typical purity of 98.36% and a molecular weight of 422.54 g/mol.
- Potent inhibition of LIMK1 and LIMK2 (IC50 84 nM and 39 nM).
- Allosteric mode of action with high selectivity against the kinome.
- Provided as a ready-to-use 10 mM solution in DMSO for in vitro studies.
- High purity suitable for research applications.
- Molecular formula C24H26N2O3S and molecular weight 422.54 g/mol.
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