Microplate Covers
Cayman Chemical pNA Stndard 50uL
A riboside form of nicotinamide a precursor of NAD and a source of vitamin B3 increases intracellular and mitochondrial NAD content in C2C12 Hepa1.6 and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1000 M decreases acetylation of FOXO1 and SOD2 but not tubulin increases NAD levels in liver and skeletal muscle and prevents body weight gain in mice fed a high-fat diet when used at a dose of 400 mg/kg per day increases NAD in the cerebral cortex and reduces cognitive deterioration in a transgenic mouse model of Alzheimers disease
Cayman Chemical 96-Wel Cover Sheet 5ea
A multi-kinase inhibitor selectively inhibits MET VEGFR2 Axl and Mer (IC50s 3 15 5.8 and 0.6 nM respectively) over serine/threonine kinases for which it has no activity but does inhibit 28 additional RTKs (IC50s 3-54 nM) and additional kinases by greater than 70 at 1 UM inhibits the proliferation of SNU-5 cells (IC50 98.9 nM) and HUVECs (IC50 10.4 nM) reduces tumor volume and intratumoral MET phosphorylation in NCI H441 and SNU-5 mouse xenograft models at 3 and 10 mg/kg increases the number of peripheral B cells and CD4 T cells and decreases the number of peripheral myeloid cells in an MC-38 syngeneic mouse model of colon carcinoma at 30 mg/kg
Cayman Chemical IgG2humn ELISA Stndard 1ea
An EP1 receptor antagonist (Kis 0.6 and 1.7 nM for human and mouse receptors respectively expressed in CHO cells) is selective for EP1 over EP2 EP3 and EP4 (Kis 1000 67 and 1000 nM respectively for mouse receptors expressed in CHO cells) inhibits PGE2-induced increases in intracellular calcium concentrations in cells expressing human or mouse EP1 (EC50s 50 and 210 nM respectively) reduces the incidence of squamous cell carcinoma and severe dysplasia induced by 4-nitroquinoline 1-oxide in a rat model of tongue carcinogenesis at 400 and 800 ppm in the diet
Revvity Health Sciences Inc 2 Place Microtitration Plate Swing Out Rotor
2 Place Microtitration Plate Swing Out Rotor
Glass Expansion PuraFlex Transfer Tube GAZ08-FB13-105
PuraFlex Transfer Tube GAZ08-FB13-105 Sourced from Glass Expansion
Cayman Chemical LeukotrIen C4 EIA Stndard 1ea
An antagonist of NR2B subunit-containing NMDA receptors (Ki 72 nM) selective for NR2B subunit-containing NMDA receptors over those containing NR2A subunits (IC50s 47 and 10000 nM respectively) reduces carrageenan-induced hyperalgesia in rats (ED50 5.5 mg/kg) reduces dopaminergic neuron loss in the rat substantia nigra pars compacta and improves measures of ipsilateral curling ipsilateral head positioning and beam walking in a rat model of 6-OHDA-induced Parkinsons disease at 10 mg/kg
Electron Microscopy Sciences PCRSeal™ PCRSeal Microplate Sealing Film, PRC, qPCR, -70°C to 100°C
Pre-cut adhesive films for micropalte sealing eliminate well-to-well contamination, microbial and viral contamination, evaporation (excluding breathable membranes) and sample spillage. The pre-cut adhesive films fit all microplates and are sterilized by gamma irradiation and free of cytotoxins. Two scored end-tabs make film positioning and removal hassle-free. Pierceable sealing films facilitate easy removal of samples with a pipet tip. PCRSeal™ has a high optical quality, minimal autofluorescence and resists DMSO and organic solvents. It is RNase and DNase free.
Use: PRC, qPCR
Range: -70°C to 100°C
Thickness: 2 mil
Material: Polyester
Size: 6" x 3.25"
Sigma Aldrich Fine Chemicals Biosciences ThermalSeal RTSTM Sealing
ThermalSeal RTS(TM) sealing film is a 50 mum thick polyolefin with 50 mum inert encapsulated silicone adhesive. They are optically clear with low autofluorescence and are especially suited for real-time qPCR storage and protein crystallization applications. The encapsulated silicone adhesive is non-tacky until pressed against the sealing surface at which time adhesive is released only in sealing areas to form the strongest available heat-resistant seal around each well on the plate. Adhesive on non-sealing areas of the film such as directly over sample wells remains encapsulated and inert.ThermalSeal RTS(TM) films are sized to fit within the edges of raised-rim 96-well plates. Their consistent high optical clarity makes possible reproducible reliable and consistent DNA amplification measurements and crystal detection. Two end tabs assist in positioning the film on the plate and the non-tacky adhesive surface simplifies handling. Easy removal of the end tabs at perforated boun