ELISA Substrates and Reagents
ABclonal Technology Phospho-PPP1CA-T320 Rabbit pAb
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). This broadly expressed gene encodes the alpha subunit of the PP1 complex that associates with over 200 regulatory proteins to form holoenzymes which dephosphorylate their biological targets with high specificity. PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies suggest that PP1 is an important regulator of cardiac function and that PP1 deregulation is implicated in diabetes and multiple types of cancer. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
American Research Products Inc Mouse Osteopontin OPN ELISA
Mouse Osteopontin (OPN) ELISA Kit from CUSABIO Detection Range 78 pg/ml-5000 pg/ml Sensitivity 19 5 pg/ml Sample serum plasma cell culture supernates tissue homogenates Method Sandwich
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3900720 1-HYDROXYMIDAZOLAM
Biolegend TotalSeqTM-C1127 anti-RPS6
TotalSeq -C1127 anti-RPS6 [A16009C] Isotype Mouse IgG2b Reactivity Human Mouse Apps ICPG Size 10 g
ABclonal Technology 594 anti-h CD235a
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups In addition to the M or N and S or s antigens that commonly occur in all populations about 40 related variant phenotypes have been identified These variants include all the variants of the Miltenberger complex and several isoforms of Sta as well as Dantu Sat He Mg and deletion variants Ena S-s-U- and Mk Most of the variants are the result of gene recombinations between GYPA and GYPB
Immunology Consultants anti-Hamster (CHO) Legumain Antibody - Affinity Purified
This affinity‑purified antibody targets hamster (CHO) Legumain, a lysosomal cysteine protease involved in protein processing, antigen presentation, and cellular stress responses. Produced in chicken and purified to high specificity, it provides reliable detection of Legumain across CHO‑derived lysates, purified preparations, and process‑related impurity panels. Its robust performance makes it well suited for bioprocess monitoring, host cell protein characterization, and development of quantitative immunoassays. The antibody’s avian origin minimizes background in mammalian systems, supporting sensitive detection in ELISA, Western blotting, and other analytical workflows requiring consistent lot‑to‑lot performance.
Cayman Chemical 11keto TStosTRon ELISA n
A DGAT1 inhibitor (IC50 57 nM) selective for DGAT1 over DGAT2 ACAT-1 and ACAT-2 (IC50s >10000 nM for all) inhibits HCV replication in HCV-infected Huh7.5 cells at 50 UM. inhibits palmitic acid-induced apoptosis and increases in triglyceride levels in MIN6 cells decreases serum triglyceride levels in an oral lipid tolerance test in dogs at 1 mg/kg
ABclonal Technology Phospho-NF-kB p65/RelA-S468 Rabbit pAb
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology Phospho-SRC Family-Y416 Rabbit pAb
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
ABclonal Technology Phospho-ALOX5-S271 Rabbit pAb
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Surmodics Inc TMB One Component HRP Microwell Substrate, 1mL
The BioFX™ one component 3,3’,5,5’-tetramethylbenzidine (TMB) substrate is supplied in a ready-to-use solution. Peroxidase reacts with the TMB substrate solution to produce a soluble blue reaction product that can be read at 370 nm or 620-650 nm for ELISA applications. Stop solutions can be added to prevent further color development and reading the absorbance values at the desired wavelengths.