ELISA Substrates and Reagents
ABclonal Technology pJNK1/2/3-T183/Y185/T221/Y223
The protein encoded by this gene is a member of the MAP kinase family MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation differentiation transcription regulation and development This kinase is activated by various cell stimuli and targets specific transcription factors and thus mediates immediate-early gene expression in response to cell stimuli The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis This kinase is also involved in UV radiation induced apoptosis which is thought to be related to cytochrom c-mediated cell death pathway Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation apoptosis and differentiation Several alternatively spliced transcript variants encoding distinct isoforms have been reported [provided by RefSeq Apr 2016]
Cayman Chemical p38a MAPK-IN-1 10mg
A p38α MAPK inhibitor (IC50 = 5,500 nM in an HTRF assay); inhibits LPS-induced TNF-α production in THP-1 cells (EC50 = 6,200 nM); has been used in the study of p38α MAPK inhibitor binding interactions and kinetics
ABclonal Technology Phospho-PEA15-S104 Rabbit pAb
This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.
TRANE Technologies STATIONARY BRACKET KIT- FTU 4000 SERIES
Accessory for 4000 Series Controlled Rate Chamber
ACROBiosystems - 96tests
This ELISA Buffer Set-96T contains a High-bind 96well plate coating buffer washing buffer blocking buffer substrate solution and stop solution. The ELISA Buffer Set-96T can be quickly applied to the ELISA experiment and save your time to prepare buffers. This ELISA Buffer Set-96T is sterile-filtered.
ABclonal Technology Phospho-GSK3β-S9 Rabbit pAb
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
ABclonal Technology Phospho-Filamin A-S2152 Rabbit pAb
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Medchemexpress LLC Recombinant rat discoidin domain receptor 2 (DDR2), His-tag | 98.0% | 100 UG
Recombinant rat discoidin domain receptor 2 (DDR2) expressed in HEK293 mammalian cells with a C-terminal His tag. This purified, glycosylated protein is supplied for biochemical, receptor binding, and cell-based assays, and is suitable for signaling and functional studies. Purity is listed at 98% and the molecular weight is approximately 50-70 kDa due to glycosylation.
- HEK293-expressed, mammalian-derived protein.
- C-terminal His tag for purification and detection.
- High purity suitable for biochemical and cell-based assays.
- Glycosylated form reflects native molecular weight (≈50-70 kDa).
- Available in multiple sizes, including 100 μg.
Medchemexpress LLC Spondin-2/SPON2 Protein, Human (HEK293, His) | ≥ 95% | Approximately 38-47 kDa | 250 UG
Spondin-2/SPON2 Protein, Human (HEK293, His) | ≥ 95% | Approximately 38-47 kDa | 250 UG
ABclonal Technology Phospho-SHP2-Y542 Rabbit pAb
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Medchemexpress LLC Phospho-AKT(S473) Antibody (YA5759) | 56 kDa | 10 UL
Phospho-AKT(S473) Antibody (YA5759) is a mouse-derived, non-conjugated monoclonal antibody specifically designed to target Phospho-AKT(S473). This antibody is supplied in a liquid formulation containing PBS, 50% glycerol, 0.5% BSA, and 0.02% sodium azide. It is purified through affinity chromatography, ensuring high specificity for research applications.
- For research use only
- Monoclonal antibody, mouse-derived
- Targets Phospho-AKT(S473)
- Supplied in PBS with 50% glycerol, 0.5% BSA, 0.02% sodium azide
- Appearance: liquid
- Storage at -20°C for up to 1 year
- Avoid repeated freeze/thaw cycles
- Shipped with blue ice
Medchemexpress LLC Phospho-AKT(S473) Antibody (YA5759) | 56 kDa | 100 UL
Phospho-AKT(S473) Antibody (YA5759) is a mouse-derived, non-conjugated monoclonal antibody targeting Phospho-AKT(S473). AKT protein is crucial in regulating cellular processes like metabolism, proliferation, cell survival, growth, and angiogenesis, functioning through serine and/or threonine phosphorylation of numerous downstream substrates.
- Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
- Stored at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
- Shipping with blue ice
- Suitable for WB, IHC-P, and ICC/IF applications
Medchemexpress LLC Phospho-AKT(S473) antibody (YA5759) | 56 kDa | 50 UL
Phospho-AKT(S473) antibody (YA5759) is a mouse-derived, non-conjugated monoclonal antibody targeting Phospho-AKT(S473). The AKT protein, a member of the AKT kinase family, is pivotal in regulating cellular processes including metabolism, proliferation, survival, growth, and angiogenesis. It functions by phosphorylating numerous downstream substrates, with AKT1 involved in modulating over 100 candidates, orchestrating glucose uptake and storage, protein synthesis, and lipid metabolism. This antibody is a key tool for research into these complex cellular pathways.
- Formulation: supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Purity: affinity chromatography.
- Storage and stability: stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
- Appearance: liquid.
- Applications: WB (1:1000-2000), IHC-P (1:100-200), ICC/IF (1:50-200).
- Shipping: shipped with blue ice.
Cayman Chemical Testosteron ELISA Stndard 1ea
A phospholipid has been used in the generation of LNPs for the delivery of mRNA in vivo has been used in the synthesis of various PEG-conjUGates for incorporation into liposomes LNPs containing 12-dierucoyl-sn-glycero-3-PE and encapsulating mRNA encoding hEPO increase serum hEPO levels in mice