Protein Molecular Weight Markers
ABclonal Technology PKD1L2 Rabbit pAb
This gene encodes a member of the polycystin protein family. This protein may function as a G-protein-coupled component or regulator of cation channel pores. The long isoform of this protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene is a polymorphic pseudogene in humans.
ABclonal Technology TMC5 Rabbit pAb
Predicted to enable mechanosensitive ion channel activity. Predicted to be involved in ion transmembrane transport. Located in extracellular exosome.
ABclonal Technology S100A10 Rabbit pAb
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis.
ABclonal Technology IGFBPL1 Rabbit pAb
Predicted to enable insulin-like growth factor binding activity. Involved in cellular response to tumor cell. Located in extracellular space.
ABclonal Technology CASP8AP2 Rabbit pAb
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
ABclonal Technology FKBP1B Rabbit pAb
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
ABclonal Technology TRMT112 Rabbit pAb
Enables protein heterodimerization activity and protein methyltransferase activity. Involved in macromolecule methylation and positive regulation of rRNA processing. Located in nucleoplasm and perinuclear region of cytoplasm. Part of protein-containing complex.
Biotium Primary Antibody PSD95 rK28/43 CF740 1/EA
PSD95 (rK28/43)is a recombinant mouse monoclonal antibody that recognizes PSD95 This CF740 antibody conjugate has been validated in Immunofluorescence CF and reg dyes are Biotiums line of next-generation fluorescent dyes with advantages in brightness and photostability
ABclonal Technology DCSTAMP Rabbit pAb
This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants.
ABclonal Technology HNRNPCL1 Rabbit pAb
Enables identical protein binding activity. Predicted to be active in nucleus.
ABclonal Technology CHRNA7 Rabbit pAb
The nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels involved in fast synaptic signaling. These receptors are typically hetero-pentamers of homologous subunits, with each subunit containing a conserved extracellular N-terminal domain, three transmembrane domains, a variable cytoplasmic loop, a fourth transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel that is permeable to calcium ions and is a major component of brain nicotinic receptors. This receptor, sensitive to alpha-bungarotoxin, opens upon acetylcholine binding. This gene is linked to juvenile myoclonic epilepsy and schizophrenia. A partial duplication event in this region forms a hybrid gene with the novel FAM7A gene. Alternative splicing results in multiple transcript variants.
ABclonal Technology ENPP3 Rabbit pAb
The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene.
ABclonal Technology IPO11 Rabbit pAb
Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1, 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]).
ABclonal Technology ANKHD1 Rabbit pAb
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.
ABclonal Technology GSPT1 Rabbit pAb
Enables translation release factor activity. Involved in regulation of translational termination. Acts upstream of or within protein methylation. Predicted to be located in cytosol. Predicted to be part of translation release factor complex.