Protein Molecular Weight Markers
ABclonal Technology TPMT Rabbit pAb
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.
ABclonal Technology TRNAU1AP Rabbit pAb
Enables RNA binding activity. Predicted to be involved in selenocysteine incorporation. Predicted to be located in cytoplasm. Predicted to be active in nucleus.
ABclonal Technology LYRM1 Rabbit pAb
The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants.
ACROBiosystems Star Ribbon Pre-stained Protein Marker (8-180 kDa)
This product is a mixture of ten highly purified pre-stained proteins ranging from 8 kDa to 180 kDa. The 72 kDa band is orange, 8 kDa band is green, and other bands are blue. It is designed for observing protein separation during SDS-PAGE, verifying western transfer efficiency on membranes, and approximating the size of proteins.
ABclonal Technology FGGY Rabbit pAb
This gene encodes a protein that phosphorylates carbohydrates such as ribulose, ribitol, and L-arabinitol. Genome-wide association studies in some populations have found an association between polymorphisms in this gene and sporadic amyotrophic lateral sclerosis, but studies of other populations have not been able to replicate this association. Alternative splicing results in multiple transcript variants.
S2 Media 15x100mm Chameleon™ COLOREX Salmonella, 10/pack
Chameleon™ COLOREX Salmonella is a selective and differential, chromogenic culture medium used for the qualitative direct detection and presumptive identification of Salmonella. Test specimens include rectal swabs and stools. Concomitant cultures should be performed to recover organisms for further microbiological testing or epidemiological typing. Further identification, susceptibility testing, and epidemiological typing should be performed on suspect colonies. • Product meets CLSI performance criteria.• Chameleon™ COLOREX™ Salmonella should be used by trained professionals within a laboratory setting. • For in vitro diagnostic (IVD) use.• Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
ACROBiosystems Star Ribbon Pre-stained Protein Marker (2.7-40 kDa)
This product is a mixture of nine highly purified pre-stained proteins ranging from 2.7 kDa to 40 kDa. The 40 kDa band is orange, 10 kDa band is green, and other bands are blue. It is designed for observing protein separation during SDS-PAGE, verifying western transfer efficiency on membranes, and approximating the size of proteins.
ABclonal Technology PPA2 Rabbit pAb
The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
ABclonal Technology WNK3 Rabbit pAb
This gene encodes a protein belonging to the with no lysine family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.
ABclonal Technology ERAL1 Rabbit pAb
The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3 terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology HDAC9 Rabbit pAb
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
![ABclonal Technology [KO Validated] MYOF Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000104718.jpg-250.jpg)
ABclonal Technology [KO Validated] MYOF Rabbit pAb
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
ABclonal Technology UNC93B1 Rabbit pAb
This gene encodes a protein that is involved in innate and adaptive immune response by regulating toll-like receptor signaling. The encoded protein traffics nucleotide sensing toll-like receptors to the endolysosome from the endoplasmic reticulum. Deficiency of the encoded protein has been associated with herpes simplex encephalitis.
S2 Media 15x100mm Chameleon™ COLOREX™ ECC, 10/pack
Chameleon™ COLOREX™ ECC is a selective and differential, chromogenic medium used for the detection and enumeration of ß-glucuronidase positive Escherichia coli and coliforms in food, water and environmental samples.• Product meets CLSI performance criteria.• Chameleon™ COLOREX™ ECC should be used by trained professionals within a laboratory setting. • Product is not intended for use in the diagnosis or treatment of disease or other human conditions.
