Protein Molecular Weight Markers
ABclonal Technology DICER1 Rabbit pAb
This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. This protein also acts as a strong antiviral agent with activity against RNA viruses, including the Zika and SARS-CoV-2 viruses. Alternative splicing results in multiple transcript variants.
ABclonal Technology SUGP2 Rabbit pAb
This gene encodes a member of the arginine/serine-rich family of splicing factors. The encoded protein functions in mRNA processing. Alternatively spliced transcript variants have been described.
ABclonal Technology ACOT9 Rabbit pAb
The protein encoded by this gene is a mitochondrial acyl-CoA thioesterase of unknown function. Two transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology MMP25 Rabbit pAb
Proteins in the matrix metalloproteinase (MMP) family break down the extracellular matrix in processes like development, tissue remodeling, and disease progression, including arthritis and metastasis. Most MMPs are secreted as inactive proproteins, activated by extracellular proteinases. This gene encodes a membrane-type MMP (MT-MMP), anchored to the plasma membrane via a glycosylphosphatidylinositol anchor. In response to infection or inflammation, the protein inactivates alpha-1 proteinase inhibitor, aiding neutrophil migration to inflammation sites. It may also contribute to tumor invasion and metastasis by activating MMP2. The gene, formerly known as MMP20, is now renamed MMP25.
ABclonal Technology CHRNA7 Rabbit pAb
The nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels involved in fast synaptic signaling. These receptors are typically hetero-pentamers of homologous subunits, with each subunit containing a conserved extracellular N-terminal domain, three transmembrane domains, a variable cytoplasmic loop, a fourth transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel that is permeable to calcium ions and is a major component of brain nicotinic receptors. This receptor, sensitive to alpha-bungarotoxin, opens upon acetylcholine binding. This gene is linked to juvenile myoclonic epilepsy and schizophrenia. A partial duplication event in this region forms a hybrid gene with the novel FAM7A gene. Alternative splicing results in multiple transcript variants.
ABclonal Technology MYOCD Rabbit pAb
This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology EDC4 Rabbit pAb
Predicted to be involved in deadenylation-independent decapping of nuclear-transcribed mRNA. Located in P-body and nucleoplasm.
ABclonal Technology TEKT1 Rabbit pAb
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse, tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules, indicating that it may play a role in spermatogenesis.
ABclonal Technology RTBDN Rabbit pAb
This gene was first identified in a study of human eye tissues. The protein encoded by this gene is preferentially expressed in the retina and may play a role in binding retinoids and other carotenoids as it shares homology with riboflavin binding proteins. Alternative splicing results in multiple transcript variants and protein isoforms.
ABclonal Technology HOXA13 Rabbit pAb
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
Immunology Consultants 12 Epitope Tag Control, 0.2 ml
This protein solution contains a 41kDa alpha tubulin fragement with 12 commonly used epitope tags that is intended for use as a positive control in Western Blot assays.GST – T7 – HSV – C-MYC – VSV – Glu-Glu – V5 – E-tag – DYKDDDDK (Sigma Flag) – S-tag – HA - 6xHIS.