Protein Molecular Weight Markers
ABclonal Technology NOP14 Rabbit pAb
This gene encodes a protein that plays a role in pre-18s rRNA processing and small ribosomal subunit assembly. The encoded protein may be involved in the regulation of pancreatic cancer cell proliferation and migration. Alternative splicing results in multiple transcript variants.
ABclonal Technology AMPKα2 Rabbit pAb
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
ABclonal Technology SMNDC1 Rabbit pAb
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
ABclonal Technology DIAPH2 Rabbit pAb
The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified.
ABclonal Technology RPRD1B Rabbit pAb
Enables RNA polymerase II complex binding activity and identical protein binding activity. Involved in positive regulation of cell population proliferation, regulation of cell cycle process, and regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of RNA polymerase II, holoenzyme.
ABclonal Technology eEF1A1 Rabbit pAb
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes.
ABclonal Technology THUMPD3 Rabbit pAb
Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. Located in cytosol and nucleolus.
FUJIFILM BIOSCIENCES INC WIDE-VIEW TM Prestained Protein Size Marker Ⅲ
A stained protein size marker. There are twelve recombinant proteins contained, and they covalently bind to blue,red and green chromophores. A band for 75 kDa shows red, 25 kDa shows green and other bands exhibit blue color.
ABclonal Technology PERP Rabbit mAb
Involved in activation of cysteine-type endopeptidase activity. Predicted to be located in plasma membrane. Predicted to be active in cell-cell junction. Implicated in erythrokeratodermia variabilis and mutilating palmoplantar keratoderma with periorificial keratotic plaques.
Rockland Immunochemicals OspB Control Protein 100 µg
OspB is one of the major Outer Surface Proteins of the outer membrane of Borrelia burgdorferi which is composed of various unique outer surface proteins (Osp) that have been characterized (OspA through OspF). The Osp proteins are lipoproteins anchored by N-terminally attached fatty acid molecules to the membrane. They are presumed to play a role in virulence transmission or survival in the tick. Two of the major surface Ag of Borrelia burgdorferi the 31-kDa OspA and 34-kDa OspB proteins show a high degree of sequence similarity are encoded by a 49-kb plasmid and share a common promoter and are coordinately transcribed. The C terminus of OspB is important for eliciting a protective immune response to OspB. B. burgdorferi has the ability to vary its surface proteins in response to immune attack.
Rockland Immunochemicals OspA Control Protein 100 µg
Outer-Surface Protein A (OspA) a lipoprotein from Borrelia burgdorferi encoded on its Plasmid lp54 is a major component of the spirochete's extracellular matrix. OspA probably serves as a lipid-anchor. The spirochetes migrate from the tick midgut during feeding to its salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. Upon transmission of the spirochete from the Ixodes tick to mammalian host the transcript level of OspA can change. B. burgdorferi can attach to diverse tissues within the vertebrate host and the tick vector suggesting that physiological factors other than pH and temperature may play roles in modulating B. burgdorferi gene expression.
ABclonal Technology NUMB Rabbit mAb
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.
Abcam Prestained Protein Ladder - Mid-range molecular weight (10 - 180 kDa), 500UL
Prestained Protein Ladder ab234617 is a blue protein standard with 11 pre-stained proteins covering a range of MW from 10-180 kDa. ab234617 is designed for monitoring protein seperation in SDS-polyacrylamide gel electrophoresis and verifying Western transfer efficiency on membranes (PVDF, nylon, or nitrocellulose) and for approximating the size of proteins.
The product is subject to the following: Abcam Restricted Use Statement