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Benzyl-PEG45-alcohol is a PEG-based PROTAC linker essential for the synthesis of PROTACs. These compounds exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins, achieved by connecting two ligands-one for an E3 ubiquitin ligase and another for the target protein-via this linker.
PEG-based PROTAC linker
Utilized in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system
Designed for selective degradation of target proteins
Connects two different ligands: one for an E3 ubiquitin ligase, one for a target protein
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Benzyl-PEG45-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Purity: 98.56%
Appearance: Solid
Color: White to off-white
For research use only
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Benzyl-PEG45-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PROTACs contain two different ligands connected by a linker.
One ligand binds to an E3 ubiquitin ligase and the other to the target protein.
Enables selective degradation of target proteins.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Benzyl-PEG45-alcohol is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs are compounds that exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Consists of two different ligands connected by a linker
One ligand targets an E3 ubiquitin ligase
The other ligand targets the protein of interest
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Benzyl-PEG45-alcohol is a polyethylene glycol (PEG)-based linker bearing a benzyl-protected terminal alcohol, designed for use in the synthesis of proteolysis targeting chimeras (PROTACs). It provides a flexible spacer between ligands and is supplied as a high-purity solid suitable for research applications.
PEG-based linker with benzyl-protected terminal alcohol.
Designed for use in PROTAC synthesis and bioconjugation.
High purity (98.6%) for research-grade applications.
Molecular weight approximately 2090.5 g/mol.
Supplied as a solid in multiple package sizes for flexible use.
Store sealed, away from moisture; follow cold storage guidance for solutions.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More