Oligonucleotides
Biotium CD43 (T-Cell Marker) (SPN/1766R), 1mg/mL
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundan
ABclonal Technology RALA Rabbit pAb
The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins.
Vector Biolabs codon-improved Cre (iCre) and RFP Adenovirus (Ad-RFP-Cre)
Ready to use in vivo grade AAV and Adenovirus Ready to use in vivo grade AAV and Adenovirus pre synthesized DNA vector High titer viral vectors 1/EA
Biotium SOX9 / SRY-box 9 (PCRP-SOX9-1E5), CF488A conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are n
Medchemexpress LLC GAPDH Human HEK293 5ug | 5ug
The GAPDH protein has dual roles in glycolysis and nuclear function It also affects the organization and assembly of the cytoskeleton and promotes the association of microtubules and membranes GAPDH Protein Human (HEK293 His) is the recombinant human-derived GAPDH protein expressed by HEK293 with N-6 His labeled tag
ABclonal Technology GAPDH Rabbit pAb
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase family, known as a moonlighting protein due to its multiple distinct functions. It catalyzes an important step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate with NAD and inorganic phosphate. The protein also has uracil DNA glycosylase activity in the nucleus and antimicrobial properties against E. coli, P. aeruginosa, and C. albicans. Additionally, similar proteins in mice have been linked to regulating mRNA stability, nitrosylating nuclear proteins, and acting as a transferrin receptor on macrophage surfaces. Many pseudogenes related to this gene exist in the human genome. Alternative splicing generates multiple transcript variants.
Biotium DNA Ligase 1(1A9), 0.2mg/mL
DNA Ligase I maintains the major DNA Ligase activity in proliferating cells by joining Okazaki fragments during lagging strand DNA replication. Human DNA Ligase I also has an essential role in DNA repair pathways, where it catalyzes the formation of phosphodiester bonds between adjacent 5' phosphoryl and 3' hydroxy termini at single breaks in duplex DNA molecules. In addition, DNA Ligase I plays a role in sealing nicks during excision repair. Similar to other DNA ligases, DNA Ligase I is built around a common catalytic core. Increased levels of DNA Ligase I are found in human tumors, as compared to benign tissues, as well as in peripheral blood lymphocytes. DNA Ligase I activity is altered in the chromosomal breakage deficit Bloom's syndrome (BS). Individuals with BS either have decreased levels of abnormally thermolabile DNA Ligase I or possess a dimeric form of this enzyme. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. C
Biotium SOX9 / SRY-box 9 (PCRP-SOX9-1E5), 1 mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are n
Apexbio Technology LLC EZ Cap Human PTEN mRNA 5x1mg (1mg/mL)
PTEN mRNA encodes a a tumor suppressor gene (Phosphatase and Tensin homolog deleted on chromosome 10) that antagonizes the activity of PI3K a key enzyme involved in anti-apoptotic and pro-tumorigenic Akt activation EZ Cap Human PTEN mRNA is provided at 1 mg/mL This mRNA is synthesized through co-transcriptional capping resulting in a Cap 1 structure The addition of poly(A) tail significantly enhances mRNA stability and lifetime both in vitro and in vivo Furthermore the poly(A) tail significantly contributes to improving the efficiency of translation initiation
Cayman Chemical Cre mRNACap-1UTP 100ug
An mRNA for the expression of Cre; encapsulation in LNPs can be used for mRNA delivery and expression of Cre in vitro or in vivo
Hach Company SC4500 Ctrl C1D2 Prog 5x mA Ou
SC4500 Controller-C1D2-Prognosys-5x mA Output-1 mA Input-24 VDC-without plugIncludes SC4500 Controller-Claros-enabled-with EU plug includes mounting hardware
Biotium PAX2 (Renal Cell & Ovarian Carcinoma Marker) (PAX2/1104), CF740 conjugate, 0.1mg/mL
This antibody recognizes a protein of 42 kDa, which is identified as PAX2. It is a member of the paired box family of transcription factors, which is required for development and proliferation of the kidney, brain, and Müllerian organs. PAX2 genes contain a highly conserved DNA sequence within the paired box region, which encodes a DNA-binding domain, enabling PAX proteins to bind the promoters of specific genes to transcriptionally regulate their expression. PAX2 is specifically expressed in the developing central nervous system, eye, ear, and urogenital tract, and is essential for the development of these organs. In normal adult tissues PAX2 was mainly detected in the urogenital system, including kidney, ureteric epithelium, fallopian tube epithelium, ovary and uterus. In tumors, PAX2 has been detected in renal cell carcinomas, Wilms' tumors, nephrogenic adenomas and papillary serous carcinoma of the ovary. PAX2 has been used as a marker for the identification of renal cel
Medchemexpress LLC STING ligand-3 | 2762552-73-6 | 99.2% | C15H11N3O7 | 5 MG
STING ligand-3 is supplied as a light yellow to yellow solid. This product has been rigorously tested and complies with the given specifications, exhibiting a high purity of 99.2%.
- Supplied as a light yellow to yellow solid
- High purity of 99.2% by HPLC
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In-solvent storage: -80°C for 6 months, -20°C for 1 month
- Chemical formula: C15H11N3O7
Medchemexpress LLC Seh inhibitor-7 | 340221-20-7 | 99.50% | 247.33 | 5 MG
sEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH) with IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH), respectively. Soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation.
- Inhibitor of soluble epoxide hydrolase (sEH)
- IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH)
- Plays an important role in the metabolism of endogenous chemical mediators
- Involved in the regulation of blood pressure and inflammation
Cayman Chemical Cre mRNACap-1m1 100ug
An mRNA for the expression of Cre; encapsulation in LNPs can be used for mRNA delivery and expression of Cre in vitro or in vivo