Oligonucleotides
Biotium SOX9 / SRY-box 9(rSOX9/2288), CF740 conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare, often lethal, dominantly inherited, congenital osteo-chondrodysplasia, associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones, unusually small scapulae, deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate, micrognathia, flat face and hypertelorism are common. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and phot
Abcam EI1, EZH2 inhibitor, 50MG
MW 390.5 Da. Potent (IC₅₀ = 15 nM for wild-type enzyme; 13 nM for Y641F mutant enzyme) EZH2 inhibitor. Selective versus EZH1 (142-fold). Highly selective (>10,000-fold) against a panel of 10 other human methyltransferases. Inhibits cellular H3K27 methylation and activates Ezh2 target gene p16 expression in diffuse large B-cell lymphoma cells (DLBLC). Selectively inhibits growth and promotes cell cycle arrest and apoptosis of DLBLC cells with Y641 EZH2 mutations.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SARS-CoV-2 Spike S1+S2 (mut L18F+T20N+P26S+D138Y+R190S+K417T+E484K+N501Y+D614G+H655Y+T1027I+V1176F), 100UG
SARS-CoV-2 Spike S1+S2 (mut L18F+T20N+P26S+D138Y+R190S+K417T+E484K+N501Y+D614G+H655Y+T1027I+V1176F) is a SARS-CoV-2 Fragment protein, in the 1 to 1213 aa range, expressed in Baculovirus infected insect, with >90% purity, < 1 EU/µg endotoxin level and suitable for SDS-PAGE, FuncS.
Protein/ Peptide/ Enzyme Synonyms: 2, S, Spike glycoprotein, S glycoprotein, E2, Peplomer protein
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Biotium DNA Ligase 1(1A9), Biotin conjugate, 0.1mg/mL
DNA Ligase I maintains the major DNA Ligase activity in proliferating cells by joining Okazaki fragments during lagging strand DNA replication. Human DNA Ligase I also has an essential role in DNA repair pathways, where it catalyzes the formation of phosphodiester bonds between adjacent 5' phosphoryl and 3' hydroxy termini at single breaks in duplex DNA molecules. In addition, DNA Ligase I plays a role in sealing nicks during excision repair. Similar to other DNA ligases, DNA Ligase I is built around a common catalytic core. Increased levels of DNA Ligase I are found in human tumors, as compared to benign tissues, as well as in peripheral blood lymphocytes. DNA Ligase I activity is altered in the chromosomal breakage deficit Bloom's syndrome (BS). Individuals with BS either have decreased levels of abnormally thermolabile DNA Ligase I or possess a dimeric form of this enzyme. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. C
Medchemexpress LLC Cellular retinoic acid-binding protein 1, human recombinant | >95.0% | 50 UG
Recombinant human cellular retinoic acid-binding protein 1 (CRABP1), expressed in E. coli and supplied tag-free as a lyophilized powder. Supplied as a 50 μg unit, the protein is >95% pure, ~14 kDa, full length (M1-E137), formulated in 50 mM Tris-HCl, 300 mM NaCl, pH 8.0, 10% glycerol, with endotoxin <1 EU/μg. Store at -20°C; reconstitute to at least 100 μg/mL in ddH2O and follow laboratory handling procedures.
- Recombinant human protein expressed in E. coli.
- Tag free preparation suitable for functional assays.
- Purity greater than 95% by reducing SDS-PAGE.
- Approximate molecular weight of 14 kDa.
- Lyophilized powder formulation for long-term storage.
- Low endotoxin level (<1 EU/μg) for sensitive applications.
- Reconstitution recommended to at least 100 μg/mL in ddH2O.
- Stable at 4°C for 1 week after reconstitution or at -20°C for long-term storage with carrier protein.
BIOHIPPO AAV-CS-CRM4-aMHC-Cre-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre under the CS-CRM4-aMHC promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-CaMKIIa-C1V1-(t/t)-TS-EYFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing C1V1 (t/t) fused to EYFP under the CaMKIIa promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
ABclonal Technology PRKRA/PACT Rabbit mAb
This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants.
New England Biolabs, Inc. Duplex DNase - 5000 units
An engineered double-strand specific DNA endonuclease, dsDNase preferentially degrades double-stranded DNA (dsDNA) over single-stranded DNA (ssDNA) or RNA. This specificity toward dsDNA allows the enzyme to degrade contaminating dsDNA while maintaining the integrity of single stranded DNA molecules such as primers and probes within PCR mixes, allowing for efficient decontamination of PCR master mixes. Moreover, dsDNase displays the unique property of cleaving the DNA strand of a DNA:RNA hybrid duplex.
ABclonal Technology Phospho-EZH2/KMT6-T311 Rabbit pAb
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
BIOHIPPO AAV-CAG-Cre-EGFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre fused to EGFP under the CAG promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
BIOHIPPO AAV-ChAT-Cre-P2A-EGFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing Cre fused to EGFP under the ChAT promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Cayman Chemical ZngIbrosIde R1 25mg
A triterpene saponin and an active metabolite of ginsenoside Ro; cytotoxic to B16/F10 murine melanoma cells (IC50 = 24.52 UG/ml); inhibits tube formation by HUVECs at 40 UG/ml; reduces tumor growth in a B16/F10 murine melanoma model at 25 mg/kg
ABclonal Technology AFTMag Quick Gel DNA Extraction Kit
This kit uses magnetic bead-based technology for nucleic acid purification. It utilizes functional groups on magnetic beads to enrich nucleic acids from agarose gel onto the bead surface.The beads are then washed to remove impurities, and then separate magnetic beads with magnetic separation device, so as to quickly separate and purify DNA from samples. The whole process does not require the use of phenol, chloroform and β-merphytoethanol,, safe and non-toxic, and the use of paramagnetic magnetic beads, suitable for high-throughput automated extraction.
Genscript Corporation CHO-K1/CRE-CBLuc/GLP1R
Recombinant CHO-K1 cells stably overexpress human glucagon like peptide 1 receptor (GLP1R) on the surface and contain high levels of G protein G s to couple with the receptor in downstream signaling pathways