Oligonucleotides
Invivogen ODN 2006 control (ODN 2137), 1 mg
ODN 2006 Control (ODN 2137) contains GpC dinucleotides instead of CpGs and can be used as a negative control for ODN 2006 (type B, with a preference for human TLR9).
Cayman Chemical ANTIBODY SET2 10mg
A TRPV2 inhibitor (IC50 = 0.46 µM); selectively inhibits 2-APB-induced currents in a patch-clamp assay using HEK293T cells overexpressing TRPV2 at 0.3 or 1 µM over HEK293T cells overexpressing TRPV1 or TRPV3 at 3 or 10 µM; reduces LPA-induced migration in PC-3M prostate cancer cells at 20 µM; reduces LPA-induced increases in current in a patch-clamp assay using HEK293T cells
Meso Scale Discovery R-PLEX Human CCN1 ASYQP
The R-PLEX Human CCN1 Assay is a multiplex immunoassay kit for measuring CCN1 protein in human serum plasma and cell culture supernatants It uses electrochemiluminescence (ECL) on the Meso Scale Discovery (MSD) platform for sensitive detection The kit includes a 96-well plate with capture antibodies detection antibodies calibrators controls diluent and wash buffer Sample incubation is 2 hours with results in 3 5 hours Designed for research use only it requires an MSD instrument The kit offers high sensitivity accuracy and rapid results for quantifying CCN1 levels
Cayman Chemical Flos Sopoa matuus Toxutn 5g
A flavonoid with diverse biological activities; reduces D-galactose-induced increases in renal MDA levels and decreases in renal Cu/Zn SOD, catalase, and GPX activities in mice at 150 mg/kg per day, as well as attenuates D-galactose-induced increases in renal levels of NF-κB p65, iNOS, COX-2, and EP2 levels; reduces blood glucose levels, plasma triglyceride levels, heart rate, and blood pressure in a rat model of STZ-induced type 2 diabetes at 150 mg/kg per day; prevents the loss of dopaminergic neurons in the SNC and reduces apomorphine-induced contralateral rotations in a rat model of Parkinson’s disease induced by 6-OHDA at 150 mg/kg per day
ABclonal Technology SLC1A5 Rabbit pAb
The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).
ABclonal Technology EZH2/KMT6 Rabbit pAb
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
Medchemexpress LLC Seh inhibitor-7 | 340221-20-7 | >99.5% | 247.33 | 50 MG
sEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH) with IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH), respectively. Soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation.
- Inhibitor of soluble epoxide hydrolase (sEH).
- Involved in the regulation of blood pressure.
- Involved in the regulation of inflammation.
ABclonal Technology EZH2/KMT6 Rabbit pAb
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
![Biolegend TotalSeq -C1510 anti-PTEN [W20041H] Isotype Rat IgG2b Reactivity Human Apps ICPG Size 10 g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000082705.png-250.jpg)
Biolegend TotalSeq -C1510 anti-PTEN [W20041H] Isotype Rat IgG2b Reactivity Human Apps ICPG Size 10 g
TotalSeq -C1510 anti-PTEN [W20041H] Isotype Rat IgG2b Reactivity Human Apps ICPG Size 10 g
Cayman Chemical DNA MethyltrnsfRase 3a Mon 1ea
Antigen: DNMT3a expressed in bacteria The epitope was found to be located near the C-terminus (amino acids 705-908) • Host: mouse, clone 64B1446 • Isotype: IgG1κ • Cross Reactivity: (+) human and mouse DNMT3a • Application(s): ChIP, IF/ICC, IHC (paraffin), and WB • The DNMT3 family members DNMT3a and DNMT3b are strongly expressed in embryonic stem cells. Their expression is down regulated in differentiating cells and low in adult sematic tissue.
ABclonal Technology ABCA1 Rabbit mAb
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters ABC proteins transport various molecules across extra- and intracellular membranes ABC genes are divided into seven distinct subfamilies (ABC1 MDR TAP MRP ALD OABP GCN20 White) This protein is a member of the ABC1 subfamily Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes With cholesterol as its substrate this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency
ABclonal Technology Von Hippel Lindau/VHL
This gene encodes a component of a ubiquitination complex The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF) which is a transcription factor that plays a central role in the regulation of gene expression by oxygen In addition to oxygen-related gene expression this protein plays a role in many other cellular processes including cilia formation cytokine signaling regulation of senescence and formation of the extracellular matrix Variants of this gene are associated with von Hippel-Lindau syndrome pheochromocytoma erythrocytosis renal cell carcinoma and cerebellar hemangioblastoma
ABclonal Technology Von Hippel Lindau/VHL
This gene encodes a component of a ubiquitination complex The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF) which is a transcription factor that plays a central role in the regulation of gene expression by oxygen In addition to oxygen-related gene expression this protein plays a role in many other cellular processes including cilia formation cytokine signaling regulation of senescence and formation of the extracellular matrix Variants of this gene are associated with von Hippel-Lindau syndrome pheochromocytoma erythrocytosis renal cell carcinoma and cerebellar hemangioblastoma