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Filtered Search Results
Medchemexpress LLC TTA-A2 | 953778-63-7 | MFCD16628062 | 99.3% | 378.39 g/mol | C20H21F3N2O2 | 5 MG
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TTA-A2 is a potent, selective, orally active T-type voltage-gated calcium channel antagonist used in preclinical neuroscience research. It shows low-nanomolar potency against Cav3.1 and Cav3.2 channels and is supplied as a high-purity solid for laboratory use.
- Potent T-type calcium channel antagonist (IC50 ≈ 89-92 nM).
- Low-nanomolar potency against Cav3.1 and Cav3.2.
- High purity (~99.3%).
- Molecular weight 378.39 g/mol; formula C20H21F3N2O2.
- Solid form; powder stable at -20°C for up to 3 years.
- In solvent: stable at -80°C for 6 months or -20°C for 1 month.
- Intended for research use in studies of sleep disorders, epilepsy, and related neurological models.
- Available in small-mass quantities for in vitro and in vivo experiments.
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Medchemexpress LLC Sirtuin modulator 2 | 667910-69-2 | 99.2% | 349.41 | 5 MG
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Sirtuin modulator 2 (Compound 132) is a sirtuin modulator that exhibits an ED50 equal to or less than 50 μM. This product is intended for research use only.
- Sirtuin modulator with an ED50 ≤ 50 μM
- Available in various quantities (5 mg, 10 mg, 25 mg, 50 mg)
- High purity of 99.22%
- Chemical structure provided
- Solubility information available for *in vitro* and *in vivo* applications
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Medchemexpress LLC BRL-15572 dihydrochloride | 193611-72-2 | 99.8% | 479.87 | C25H29Cl3N2O | 5 MG
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BRL-15572 dihydrochloride is a selective antagonist of the human 5-HT1D receptor supplied for research use. The compound is available as a solid in multiple pack sizes and as a 10 mM solution in DMSO, and is characterized by manufacturer-provided analytical data including molecular weight and purity.
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Medchemexpress LLC Lomeguatrib | 192441-08-0 | 99.8% | 326.17 | 100 MG
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Lomeguatrib is an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor. It exhibits an IC50 of 9 nM in cell-free assays and 6 nM in MCF-7 cells.
- Acts as an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor.
- Shows an IC50 of 9 nM in cell-free assays.
- Exhibits an IC50 of 6 nM in MCF-7 cells.
- Increases the growth inhibitory effects of temozolomide in MCF-7 cells.
- Completely inactivates MGMT within 2 hours at 20 mg/kg i.p.
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Medchemexpress LLC HY-15186 100mg , GDC-0068 Ipatasertib;RG7440 CAS:1001264-89-6 Purity:98%
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Medchemexpress, HY-15186 100mg GDC-0068 Ipatasertib;RG7440 CAS:1001264-89-6 Formula:C24H32ClN5O2 IC50: 5±7 nM (Akt1), 18±10 nM (Akt2), 8±9 nM (Akt3), 3100±705 nM (PKA) Purity:98% GDC-0068 is a highly selective pan-Akt inhibitor targeting Akt1 / Akt2 / Akt3 with IC 50 of 5/18/8 nM, 620-fold selectivity over PKA. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1784252-84-1 | Medchem Express | C-021 (dihydrochloride) | 1mg | 495799537 | HY-103364A | MFCD16618393 | 540.57 | C27H43Cl2N5O2
Medchem Express | Oxypeucedanin hydrate | 5mg | 510478334 | HY-N2622 | 2643-85-8 | MFCD01725702 | 304.298 | C16H16O6
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Medchemexpress LLC Spiramycin I | 24916-50-5 | 50 MG
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Spiramycin I is a macrolide antibiotic and antiparasitic intended for research use only. It functions by binding to the 50S subunit of the ribosome, which blocks the synthesis of peptide chains.
- Acts as a macrolide antibiotic and antiparasitic
- Exhibits inhibitory activity against Gram-positive bacteria, including B. subtilis, M. luteus, S. aureus, S. epidermidis, and S. pneumoniae with MICs ranging from 0.5-8 μg/mL
- Shows cytotoxicity in cancer cells such as HeLa, KB, MCF-7, HepG2, and U87, with IC50 values between 30.51 and 34.41 μM
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Medchemexpress LLC HY-111767 10mg Medchemexpress, BAY-545 CAS:1699717-32-2 Purity:>98%
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Medchemexpress, HY-111767 10mg BAY-545 CAS:1699717-32-2 BAY-545 is a potent and selective A2B adenosine receptor antagonist, with an IC50 of 59 nM. BAY-545 also exhibits IC50s of 66, 400, 280 nM for human, mouse, rat A2B adenosine receptor in cells, respectively, and a Ki of 97 nM for human A2B adenosine receptor, with more selectivity over A1, A2A, and A3 adenosine receptor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Rad51-in-1 | 2101739-18-6 | 99.9% | 50 MG
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RAD51-IN-1 is a small-molecule inhibitor of the RAD51 recombinase, derived from B02, intended for preclinical cancer research to inhibit homologous recombination and reduce RAD51 foci formation in tumor cells.
- Inhibits RAD51-mediated homologous recombination.
- Displays cytotoxic activity in multiple human cancer cell lines with low micromolar IC50 values.
- Reported high purity (99.89%) and solid, yellow to orange physical form.
- Stable as a powder under recommended storage (powder: -20°C for years).
- Available in small solid quantities and as a 10 mM solution in DMSO for in vitro use.
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eMolecules 103548-82-9 | Medchem Express | Huperzine B | 5mg | 495802442 | HY-N2043 | MFCD01716207 | 256.349 | C16H20N2O
Ambeed | 2-Bromo-4-fluoro-5-methylaniline | 1g | 552701969 | A308725 | 1065076-39-2 | MFCD11042843 | 204.042 | C7H7BrFN
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Medchemexpress LLC IL-17 modulator 4 | 2446803-65-0 | 99.0% | C27H34N6O2 | 10MG
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IL-17 modulator 4 is a small-molecule research compound that modulates interleukin-17 (IL-17) signaling. Supplied as a solid reagent at high purity, it is intended for preclinical biochemical and cellular studies to support investigations into IL-17-related pathways and inflammation.
- High purity (99.0%) suitable for biochemical and cellular assays.
- Solid form for convenient storage and handling.
- Relevant for IL-17 pathway and inflammation research.
- Available in multiple milligram scales for dose-ranging studies.
- Molecular formula C27H34N6O2 and molecular weight 474.60 g/mol.
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MEDCHEMEXPRESS LLC HEPARAN SULFATE 5MG
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501871920 HEPARAN SULFATE 5MG
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MEDCHEMEXPRESS LLC GESTRINONE 5MG
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501871823 GESTRINONE 5MG
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MEDCHEMEXPRESS LLC ALLOPURINOL RIBOSIDE 5MG
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501871819 ALLOPURINOL RIBOSIDE 5MG
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MEDCHEMEXPRESS LLC R-GNE-140 5MG
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501871753 R-GNE-140 5MG
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