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Filtered Search Results
Medchemexpress LLC HY-100033 5mg Medchemexpress, NSC5844 CAS:140926-75-6 Purity:>98%
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Medchemexpress, HY-100033 5mg NSC5844 CAS:140926-75-6 NSC5844 is a 4-aminoquinoline derivative, with antitumor and antimalarial activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Medchem Express / DREADD agonist 21 (dihydrochloride) / 5mg / 761506071 / HY-100234A / / 2250025-92-2 / [null] / 351.280 / C17H20Cl2N4
Medchem Express / DREADD agonist 21 (dihydrochloride) / 5mg / 761506071 / HY-100234A / / 2250025-92-2 / [null] / 351.280 / C17H20Cl2N4
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eMolecules Medchem Express / S49076 / 2mg / 446262129 / HY-12965 / / 1265965-22-7 / MFCD28963943 / 438.500 / C22H22N4O4S
Medchem Express / S49076 / 2mg / 446262129 / HY-12965 / / 1265965-22-7 / MFCD28963943 / 438.500 / C22H22N4O4S
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Medchemexpress LLC HY-B0548A 500mg Medchemexpress, Hydroxyzine (dihydrochloride) CAS:2192-20-3 Purity:>98%
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Medchemexpress, HY-B0548A 500mg Hydroxyzine (dihydrochloride) CAS:2192-20-3 Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Calhex 231 hydrochloride | 2387505-78-2 | MFCD22580412 | 99.8% | 443.41 g·mol⁻¹ | C25H28Cl2N2O | 100 MG
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Calhex 231 hydrochloride is a research-grade small molecule that functions as a negative allosteric modulator of the calcium-sensing receptor (CaSR), inhibiting CaSR-mediated inositol phosphate signaling. It is supplied as a solid, high-purity material intended for in vitro research applications.
- Negative allosteric modulator of the calcium-sensing receptor (CaSR).
- Reported IC50 ≈ 0.39 μM for inhibition of CaSR-mediated inositol phosphate signaling.
- Solid powder with reported solubility in DMSO up to ~50 mM.
- High purity (≈99.8%).
- Intended for in vitro research use only.
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Medchemexpress LLC PF-4191834 50mg | 1029317-21-2 | 393.50 g·mol⁻¹ | C22H23N3O2S | 50 MG
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PF-4191834 is an orally active, non-iron-chelating, non-redox inhibitor of 5-lipoxygenase (5-LOX) used in research to probe leukotriene biosynthesis and 5-LOX-mediated pathways. It is supplied as a solid, characterized by high purity, and has documented solubility and storage recommendations for both powder and solution forms.
- Submicromolar potency against 5-LOX (reported IC50 ≈ 229 nM).
- High purity (reported 99.77%).
- Soluble in DMSO at approximately 100 mg/mL; in vivo formulation protocols documented.
- Stable as powder when stored at -20°C (up to 3 years) or 4°C (up to 2 years).
- Available in small research pack sizes including 50 mg.
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Medchemexpress LLC Tacedinaline (N-acetyldinaline) | 112522-64-2 | MFCD00866266 | 269.30 | C15H15N3O2 | 10 MG
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Tacedinaline (N-acetyldinaline) is a benzamide-class histone deacetylase (HDAC) inhibitor supplied as an analytical standard for research and analytical applications. It inhibits recombinant HDAC1, HDAC2, and HDAC3 with reported IC50 values of 0.9 μM, 0.9 μM, and 1.2 μM, respectively. The compound has molecular formula C15H15N3O2, molecular weight 269.30, and CAS number 112522-64-2.
- Intended for research and analytical applications.
- Provides a biochemical assay reference for HDAC activity.
- Reported activity against HDAC1-3 at micromolar concentrations.
- Available in small pack sizes suitable for analytical use.
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Medchemexpress LLC BX517 | 850717-64-5 | 98.0% | 282.30 | 100 MG
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BX517 is a potent and selective inhibitor of PDK1, demonstrating an IC50 of 6 nM. It effectively blocks the activation of Akt in various tumor cells with submicromolar potency. This compound exhibits significant selectivity, being at least 100-fold more selective against PDK1 compared to a panel of seven other Ser/Thr and Tyr kinases.
- Potent and selective inhibitor of PDK1
- Blocks activation of Akt in tumor cells
- Exhibits submicromolar potency
- Highly selective against other Ser/Thr and Tyr kinases
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Medchemexpress LLC Chloramphenicol palmitate | 530-43-8 | 98.25% | 25 MG
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Chloramphenicol palmitate is an orally active prodrug of Chloramphenicol, formed by the esterification of the agent with Palmitic acid. It is rapidly and completely hydrolyzed by intestinal esterase, releasing Chloramphenicol, which is an orally effective broad-spectrum antibiotic. For research use only. MedChemExpress (MCE) does not sell to patients.
- Orally active prodrug of Chloramphenicol.
- Rapidly and completely hydrolyzed by intestinal esterase.
- Releases Chloramphenicol, an orally effective broad-spectrum antibiotic.
- In vivo, chloramphenicol palmitate (10% dry formulation; p.o.; four doses) achieves steady-state plasma chloramphenicol concentrations of 5-6 μg/mL in four female beef-type calves, with an elimination half-life of 4.5 hours (chloramphenicol).
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Sigma Aldrich Fine Chemicals Biosciences Biapenem >=98% (HPLC) | 120410-24-4 | MFCD00864863 | 10MG
Biapenem >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 350.39 | 120410-24-4 | MFCD00864863 | 10MG
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Enzo Life Sciences CL-82198 (25mg). CAS: 307002-71-7
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A novel and selective inhibitor of MMP-13 (89% at 33 µM). Acts via binding to the S1' pocket of MMP-13 without metal chelation. Purity: ≥98% (TLC). Solubility: Soluble in water (25mg/ml). Long Term Storage: Ambient.
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eMolecules Medchem Express / GSK2838232 / 5mg / 446266846 / HY-15884 / / 1443460-91-0 / MFCD30207861 / 809.570 / C48H73ClN2O6
Medchem Express / GSK2838232 / 5mg / 446266846 / HY-15884 / / 1443460-91-0 / MFCD30207861 / 809.570 / C48H73ClN2O6
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Apexbio Technology LLC Secnidazole 3366-95-8 10mg
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Secnidazole (CAS 3366-95-8) is a small-molecule inhibitor targeting bacterial quorum sensing (QS) pathways It is designed to disrupt QS-regulated virulence processes thereby attenuating pathogenic potential independently of bacterial growth Secnidazole exerts its biological activity primarily through inhibition of QS-mediated mechanisms particularly in Pseudomonas aeruginosa In in vitro studies Secnidazole demonstrates inhibitory activity with an IC50 value of approximately 0 25 M in Pseudomonas aeruginosa quorum-sensing inhibition assays Based on these pharmacological properties Secnidazole holds research potential in investigations of virulence factor modulation bacterial infections such as bacterial vaginosis and parasitic protozoal infections including amoebiasis and giardiasis
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Medchemexpress LLC 4-(6-fluoro-3-oxo-3,5-dihydro-2H-pyrazolo[4,3-c]quinolin-2-yl)benzoic acid | 486449-65-4 | 98.0% | 323.28 | C17H10FN3O3 | 10 MG
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CD80-IN-3 is a small-molecule inhibitor of CD80 used in research to disrupt CD80/CD28 signaling. It shows in vitro activity (EC50 630 nM; Kd 125 nM) and is supplied as a solid or as a 10 mM solution in DMSO with manufacturer analytical data available.
- Potent CD80 inhibitor that blocks CD80/CD28 interaction (EC50 630 nM; Kd 125 nM).
- High purity (98.02%).
- Molecular weight 323.28 and formula C17H10FN3O3.
- Solid, light brown to yellow appearance; also available as a 10 mM solution in DMSO.
- Available in small research pack sizes such as 10 mg.
- For research use only; not for human or clinical use.
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Medchemexpress LLC Ruxolitinib (S enantiomer) | 941685-37-6 | 99.6% | C17H18N6 | 50 MG
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Ruxolitinib (S enantiomer), also known as S-Ruxolitinib, is the S-enantiomer of Ruxolitinib. It is an orally active and potent JAK inhibitor, widely utilized in research studies.
- Orally active and potent JAK inhibitor
- Suppresses IFNβ-induced gene expression in human small airway epithelial cells
- Reduces haematopoietic cell expansion in myeloproliferative neoplasms in vivo
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