Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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4,546 – 4,560 of 7,111 results

4,546

Medchemexpress LLC HY-50101A 10mg Medchemexpress, Mavorixafor (trihydrochloride) CAS:2309699-17-8 Purity:>98%

Medchemexpress, HY-50101A 10mg Mavorixafor (trihydrochloride) CAS:2309699-17-8 Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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4,547

Research Products International Corp Radicicol [Humicola Fuscoatra], 1 Milligram

Radicicol is a naturally occurring antibiotic and antifungal compound . It is known for its ability to inhibit the activity of heat shock protein 90 (Hsp90), a molecular chaperone that plays a crucial role in the folding and stabilization of various client proteins involved in cell signaling and regulation.

Radicicol is often used as a tool to study Hsp90-dependent processes and the functions of client proteins. Researchers use radicicol to investigate the impact of inhibiting Hsp90 on cellular pathways, protein folding, and cell viability. This compound is particularly valuable in cancer research, as many oncogenic proteins are dependent on Hsp90 for proper folding and stability.

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4,548

Medchemexpress LLC HY-112762A 5mg Medchemexpress, (E)-LHF-535 CAS: Purity:>98%

Medchemexpress, HY-112762A 5mg (E)-LHF-535 CAS: (E)-LHF-535 is the E-isomer of LHF-535. LHF-535 is an antiviral agent extracted from patent WO2013123215A2, Compound 38, has EC 50 s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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4,549

Medchemexpress LLC HY-110193 5mg Medchemexpress, SPP-86 CAS:1357349-91-7 Purity:>98%

Medchemexpress, HY-110193 5mg SPP-86 CAS:1357349-91-7 SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase , with an IC 50 of 8 nM. SPP-86 inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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4,550

Medchemexpress LLC Thiamphenicol (standard) | 15318-45-3 | 99.8% | 25 MG

Thiamphenicol (Standard) is the analytical standard of Thiamphenicol, a broad-spectrum antimicrobial antibiotic. It is a methyl-sulfonyl derivative of Chloramphenicol. This product is intended for research and analytical applications.

Mechanism of action: Thiamphenicol binds to the 50S ribosomal subunit, which inhibits protein synthesis and provides a bacteriostatic effect against gram-negative, gram-positive aerobic, and anaerobic bacteria.
Application: Used as a reference standard assay in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
Appearance: Solid, white to off-white.
Molecular weight: 356.22.
For research use only.

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4,551

Apexbio Technology LLC Erythromycin 114-07-8 1g

Erythromycin (114-07-8) is a small-molecule inhibitor targeting the bacterial 50S ribosomal subunit It is designed to inhibit bacterial protein translation thereby suppressing bacterial growth Erythromycin exerts its biological activity primarily through reversible binding to the bacterial 50S ribosomal subunit inhibiting protein synthesis Reported IC50 values typically range from 0 01 to 1 0 g/mL depending on bacterial species and strain susceptibility Based on these pharmacological properties erythromycin holds research potential in microbiological assays for ribosomal function translational mechanisms bacterial resistance studies antimicrobial susceptibility testing and cell biology research involving protein translation inhibition

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4,552

Research Products International Corp Penicillin G Potassium Salt, 25 Grams

Penicillin G potassium salt is a member of the penicillin class of antibiotics and is effective against a variety of gram-positive bacteria. As a narrow-spectrum antibiotic belonging to the beta-lactam class, it inhibits the synthesis of bacterial cell walls. It interferes with the formation of peptidoglycan, a crucial component of the bacterial cell wall. This weakens the cell wall and leads to the eventual rupture of the bacterial cell.

Penicillin G is effective against a wide range of Gram-positive bacteria, including Streptococcus, Staphylococcus, and some other species. However, it is not effective against Gram-negative bacteria due to their different cell wall structure.

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4,553

Medchemexpress LLC 4-benzhydryloxy-1-[3-(2H-tetrazol-5-yl)propyl]piperidine | 162641-16-9 | MFCD00936179 | 99.9% | 377.48 g·mol⁻¹ | C22H27N5O | 25 MG

HQL-79 is a potent, selective, and orally active inhibitor of human hematopoietic prostaglandin D synthase (H-PGDS) used as a research tool to study prostaglandin D2 synthesis, allergic responses, and inflammatory signaling. The compound is supplied at high purity with documented solubility and storage parameters to support reproducible experimental work.

Potent, selective inhibitor of hematopoietic prostaglandin D synthase (H-PGDS).
Orally active profile supports in vivo pharmacology studies.
High purity for reproducible biochemical and cellular assays.
Documented solubility in DMSO simplifies assay preparation.
Defined storage recommendations support long-term stability.
Available in small research pack sizes for screening and dose-ranging.

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4,554

Apexbio Technology LLC Lomeguatrib 192441-08-0 10mg

Lomeguatrib (CAS 192441-08-0) is a potent inhibitor of O6-alkylguanine-DNA methyltransferase (MGMT) an enzyme involved in DNA repair that mitigates the cytotoxic effects of alkylating agents In MCF-7 cells Lomeguatrib inactivates MGMT with an approximate IC50 of 6 nM By suppressing MGMT activity Lomeguatrib sensitizes MGMT-expressing cell lines such as A375P and select mutBRAF and mutNRAS melanoma models to temozolomide but does not alter sensitivity to dacarbazine Clinical investigations have demonstrated dose-dependent inactivation of MGMT in patient-derived tumor tissues and peripheral blood mononuclear cells highlighting Lomeguatrib s value as a research tool for studying MGMT-mediated resistance mechanisms in cancer

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4,555

eMolecules 325457-89-4 | Medchem Express | ICA-27243 | 5mg | 515744011 | HY-122114 | MFCD17166959 | 268.65 | C12H7ClF2N2O

Ambeed | 2-((2-(Cyclohexyl(methyl)amino)-2-oxoethyl)thio)acetic acid | 1g | 572847607 | A1010575 | 790232-10-9 | MFCD06356453 | 245.340 | C11H19NO3S

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
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4,556

Medchemexpress LLC HY-15532B 5mg Medchemexpress, SCH900776 (S-isomer) CAS:891494-64-7 Purity:>98%

Medchemexpress, HY-15532B 5mg SCH900776 (S-isomer) CAS:891494-64-7 SCH900776 S-isomer is the S-isomer of SCH900776. SCH900776 is a potent, selective and orally bioavailable inhibitor of checkpoint kinase1 (Chk1) with IC50 of 3 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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4,557

Medchemexpress LLC HY-17596 200mg Medchemexpress, Closantel CAS:57808-65-8 Purity:>98%

Medchemexpress, HY-17596 200mg Closantel CAS:57808-65-8 Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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4,558

Medchemexpress LLC Geldanamycin | 30562-34-6 | C29H40N2O9 | 50 MG

Geldanamycin is a potent Hsp90 inhibitor derived from *Streptomyces hygroscopicus*, exhibiting significant antimicrobial activity against various bacteria and anti-influenza virus H5N1 properties. It acts by binding to the N-terminal ATPase domain of Hsp90, thereby inhibiting its chaperone function and inducing apoptotic tumor cell death.

Hsp90 inhibitor
Antimicrobial activity
Anti-influenza virus H5N1 activities
Induces tumor cell death
Light yellow to orange solid appearance
High purity (99.43%)

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4,559

Selleck Chemical LLC Tanespimycin (17-AAG) S1141-5mg

Tanespimycin (17-AAG CP127374 NSC-330507 KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells Tanespimycin (17-AAG) induces apoptosis necrosis autophagy and mitophagy Phase 3

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4,560

Medchemexpress LLC Tomatidine hydrochloride | 6192-62-7 | 100 MG

Tomatidine hydrochloride is an anti-inflammatory agent that blocks NF-κB and JNK signaling pathways. It also activates autophagy in mammal cells and C. elegans. In vitro, it decreases inducible NO synthase and COX-2 expression by suppressing I-κBα phosphorylation, NF-κB nuclear translocation, and JNK activation.

Blocks NF-κB and JNK signaling.
Activates autophagy in mammal cells and C. elegans.
Decreases inducible NO synthase and COX-2 expression.
Suppresses I-κBα phosphorylation.
Inhibits NF-κB nuclear translocation.
Inhibits JNK activation.
Causes dose-dependent inhibition of LPS-induced iNOS expression.
Suppresses NF-κB binding activity.

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Antibiotics

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Medchemexpress LLC HY-50101A 10mg Medchemexpress, Mavorixafor (trihydrochloride) CAS:2309699-17-8 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Radicicol [Humicola Fuscoatra], 1 Milligram Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-112762A 5mg Medchemexpress, (E)-LHF-535 CAS: Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-110193 5mg Medchemexpress, SPP-86 CAS:1357349-91-7 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Thiamphenicol (standard) | 15318-45-3 | 99.8% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Erythromycin 114-07-8 1g Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Research Products International Corp Penicillin G Potassium Salt, 25 Grams Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4-benzhydryloxy-1-[3-(2H-tetrazol-5-yl)propyl]piperidine | 162641-16-9 | MFCD00936179 | 99.9% | 377.48 g·mol⁻¹ | C22H27N5O | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Lomeguatrib 192441-08-0 10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-15532B 5mg Medchemexpress, SCH900776 (S-isomer) CAS:891494-64-7 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-17596 200mg Medchemexpress, Closantel CAS:57808-65-8 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Geldanamycin | 30562-34-6 | C29H40N2O9 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Selleck Chemical LLC Tanespimycin (17-AAG) S1141-5mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Tomatidine hydrochloride | 6192-62-7 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More