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Filtered Search Results
Research Products International Corp Trimethoprim, 100 G
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Trimethoprim is a bacteriostatic antibiotic that inhibits bacterial dihydrofolate reductase, an enzyme involved in the synthesis of tetrahydrofolic acid. This acid is crucial for the production of nucleic acids (DNA and RNA) in bacteria. By blocking this enzyme, trimethoprim disrupts the folate synthesis pathway, leading to the inhibition of bacterial growth.
Trimethoprim is frequently used as a selective agent in culture media to isolate bacteria that are sensitive to this antibiotic. Its presence in the culture medium allows for the specific isolation of bacteria that lack resistance to trimethoprim.
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Medchemexpress LLC HY-14880B 5mg Medchemexpress, Bavisant (dihydrochloride hydrate) CAS:1103522-80-0 Purity:>98%
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Medchemexpress, HY-14880B 5mg Bavisant (dihydrochloride hydrate) CAS:1103522-80-0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15775 5mg Medchemexpress, Arginase inhibitor 1 CAS:1345808-25-4 Purity:>98%
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Medchemexpress, HY-15775 5mg Arginase inhibitor 1 CAS:1345808-25-4 Arginase inhibitor 1 is a potent inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 666211-30-9 | TENOVIN-2 | AstaTech | MFCD03717634 | 397.540 | C22H27N3O2S | 95.000 | CC(C)C(=O)Nc1ccc(NC(=S)NC(=O)c2ccc(cc2)C(C)(C)C)cc1 | 0.25g | 411869915
TENOVIN-2 | AstaTech | 666211-30-9 | MFCD03717634 | 397.540 | C22H27N3O2S | 95.000 | CC(C)C(=O)Nc1ccc(NC(=S)NC(=O)c2ccc(cc2)C(C)(C)C)cc1 | 0.25g | 411869915
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eMolecules 362003-83-6 | Medchem Express | NVP 231 | 10mg | 446263735 | HY-13945 | 431.55 | C25H25N3O2S
Pharmablock | 2-1-[(benzyloxy)carbonyl]piperidin-3-ylacetic acid | 50mg | 551212158 | PB06551 | 86827-10-3 | MFCD02179002 | 277.320 | C15H19NO4
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Enzo Life Sciences Staurosporine, (250µg), CAS Number: 62996-74-1
Apoptosis inducer. Protein kinase inhibitor. Model apoptosis inducer. Potent cell-permeable inhibitor of a variety of protein kinases, e.g. protein kinase C (PKC), CDK1/cyclin B (IC50~5nM), CDK2/cyclin A (IC50=7nM), CDK4/cyclin D (IC50=3-10µM), CDK5/p25 (IC50=4nM), GSK-3β (IC50=15nM), Pim-1 kinase (IC50=10nM).Binds do the ATP binding domain. Did not inhibit PKC-ζ. At 1µM induced apoptosis in CHO cells. Inhibits topoisomerase II directly by blocking transfer of phosphodiester bonds from DNA to active site tyrosine. Alternative Name: Antibiotic AM-2282. Formula: C28H26N4O3. MW: 466.5. CAS Number: 62996-74-1. MI: 14: 8802. Purity: ≥99% (HPLC). Appearance: Off-white to green powder. Solubility: Soluble in ethyl acetate, DMSO (25mg/ml) or dimethyl formamide (25mg/ml); only slightly soluble in chloroform and methanol. Insoluble in water. Use/Stability: Stable for at least 2 years after receipt when stored +4°C. Long Term Storage: +4°C
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Medchemexpress LLC JH-X-119-01 | 2227368-54-7 | 99.0% | 452.46 g/mol | C25H20N6O3 | 50 MG
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JH-X-119-01 is a potent, selective small-molecule inhibitor of interleukin-1 receptor-associated kinase 1 (IRAK1) with an in vitro IC50 of 9 nM. It is supplied for research use as a powder or as a 10 mM solution in DMSO, with a reported purity of 99.03% and molecular weight of 452.46 g/mol.
- Potent IRAK1 inhibition (IC50 9 nM).
- High reported purity (99.03%).
- Molecular weight 452.46 g/mol.
- Available as powder and as 10 mM DMSO solution.
- Multiple packaging sizes from milligram to gram scale.
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Medchemexpress LLC Desmethyl ferroquine (SSR97213) | 903546-18-9 | 98.0% | C22H22ClFeN3 | 10MG
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Desmethyl ferroquine (SSR97213) is the major N-monodemethylated metabolite of ferroquine, supplied as a research-grade solid for in vitro pharmacology, metabolic profiling, and analytical reference use. The material has defined purity and solubility characteristics for assay development and reference standards.
- Primary active metabolite used in antimalarial metabolism studies.
- High purity (98.0%).
- Molecular formula C22H22ClFeN3; molecular weight 419.73 g/mol.
- Soluble in DMSO (≈2.5 mg/mL); insoluble in water.
- Available in small research-scale quantities suitable for analytical work.
- Stable under recommended frozen storage for long-term use.
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Medchemexpress LLC Dub-in-3 | 924296-17-3 | 99.0% | C16H9N5O | 5 MG
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DUB-IN-3 is a potent and selective inhibitor of the deubiquitinating enzyme USP8 with an IC50 value of 0.56 μM. It shows promise for research in cancer, neurodegenerative diseases, inflammation, viral infection, and cardiovascular disease. This compound also affects the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC50 values in the 0.5-1.5 μM range.
- Potent and selective USP8 inhibitor
- Potential research applications in cancer
- Potential research applications in neurodegenerative diseases
- Potential research applications in inflammation
- Potential research applications in viral infections
- Potential research applications in cardiovascular disease
- Affects viability of HCT116 colon and PC-3 prostate cancer cell lines
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Medchemexpress LLC CRAC intermediate 1 | 1249343-86-9 | 98.5% | 223.18 | 100 MG
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CRAC intermediate 1 is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors. It is utilized in research related to inflammation and immune system diseases, and studies involving CRAC channels and calcium release-activated channels.
- Intermediate for chemical synthesis
- Used in research for CRAC channel inhibitors
- Relevant to inflammation and immune system disease studies
- Supports research on calcium release-activated channels
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eMolecules 1391067-96-1 | (2S)-2-Hydroxyglutaric Acid Octyl Ester Sodium Salt | Toronto Research Chemicals282.312 | C13H23NaO5 | 95.000 | [Na+].CCCCCCCCOC(=O)[C@@H](O)CCC([O-])=O | 50mg | 483413672
(2S)-2-Hydroxyglutaric Acid Octyl Ester Sodium Salt | Toronto Research Chemicals | 1391067-96-1282.312 | C13H23NaO5 | 95.000 | [Na+].CCCCCCCCOC(=O)[C@@H](O)CCC([O-])=O | 50mg | 483413672
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Medchemexpress LLC 2-(4-morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one | 587871-26-9 | 99.9% | 10 MG
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KU-55933 is a selective ATM kinase inhibitor used in biochemical and cellular research to probe ATM-dependent DNA damage response pathways. It exhibits low-nanomolar potency against ATM and strong selectivity versus related kinases, making it suitable for mechanistic studies and assay development.
- Selective ATM inhibitor with IC50 = 12.9 nM and Ki = 2.2 nM.
- High reported purity (≈99.9%).
- Chemical formula C21H17NO3S2 and molecular weight 395.49 g/mol.
- Available as powder and as ready-to-use DMSO solution formats.
- Suitable for biochemical assays and cell-based studies of DNA damage response.
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Sigma Aldrich Fine Chemicals Biosciences Nilutamide solid | 63612-50-0 | MFCD00864670 | 1G
Nilutamide solid | Mol Wt: 317.22 | 63612-50-0 | MFCD00864670 | 1G
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Gold Biotechnology Inc Aprotinin 25 mg
Aprotinin is a monomeric globular polypeptide derived from bovine lung tissue. It consists of a chain of 58 amino acids that fold into a stable, compact tertiary structure of the 'small SS-rich type
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Sigma Aldrich Fine Chemicals Biosciences Imipenem monohydrate >=98% (HPLC) | 74431-23-5 | MFCD09753321 | 25MG
Imipenem monohydrate >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 317.36 | 74431-23-5 | MFCD09753321 | 25MG
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