Cell Culture Growth Factors and Hormones
Genscript Corporation FGFR3 beta IIIc His Avi
Four distinct genes encoding closely related FGF receptors FGF R1-4 are known All four genes for FGF Rs encode proteins with an N-terminal signal peptide three immunoglobulin (Ig)-like domains an acid box region containing a run of acidic residues between the IgI and IgII domains a transmembrane domain and the split tyrosine-kinase domain FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation differentiation and apoptosis Plays an essential role in the regulation of chondrocyte differentiation proliferation and apoptosis and is required for normal skeleton development Regulates both osteogenesis and postnatal bone mineralization by osteoblasts
Medchemexpress LLC Receptor tyrosine-protein kinase erbB-3 (ErbB3/HER3) | >95.0% | 10 UG
Recombinant rat HER3 protein (residues S20-H641) expressed in HEK293 cells with a C-terminal His tag. The protein is glycosylated and has an apparent molecular weight of approximately 85-115 kDa. Supplied at high purity (>95% by reducing SDS-PAGE) for biochemical assays, binding studies, and antibody development.
- Expression system: HEK293 cells
- Tag: C-terminal His tag
- Sequence region: residues S20-H641
- Molecular weight: ~85-115 kDa (glycosylated)
- Purity: >95% by reducing SDS-PAGE
- Applications: biochemical assays, binding studies, antibody development
Sigma Aldrich Fine Chemicals Biosciences Transforming Growth factor
The TGfB1 gene is mapped to human chromosome 19q13.2 and codes for a 25 kDa peptide. TGf-AY1 polypeptide is produced as a precursor with hydrophobic signal sequence pro-region and mature peptide. Cleavage of the precursor at tetrabasic cleavage site results in monomers of carboxy-terminal 112 amino acids. The biologically active form of Tgfb1 exists as a disulphide-linked homodimer.
Creative Biomart Ciliary neurotrophic factor, Human CNTF
Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone and neurotrophic factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations including astrocytes. It is a hypothalamic neuropeptide that is a potent survival factor for neurons and oligodendrocytes.
Bioworld Pregnant Mare Serum Gonadotrophin (PMSG)
PMSG is a complex glycoprotein obtained from the serum of pregnant mares. This 43-63 kda protein is capable of supplementing and being substituted for the follicle stimulating gonadotrophin and interstitial cell-stimulating hormone of the anterior pituitary gland in both the male and female. Thus PMSG-Intervet stimulates development of the ovarian follicle in the female. Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder. Formulation: Pregnant Mare Serum Gonadotropin was lyophilized from a concentrated (1mg/ml) solution with no additives. Stability: Lyophilized PMSG although stable at room temperature for 3 weeks, should be stored between 2-8°C. Please avoid freeze-thaw cycles. Protein content: Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm . 2. Analysis by RP-HPLC, using a calibrated solution of PMSG as a Reference Standard. Usage: For Laboratory Research Use Only. Purity : >98%
Genscript Corporation FGFR3 beta IIIbBiotin His
Four distinct genes encoding closely related FGF receptors FGF R1-4 are known All four genes for FGF Rs encode proteins with an N-terminal signal peptide three immunoglobulin (Ig)-like domains an acid box region containing a run of acidic residues between the IgI and IgII domains a transmembrane domain and the split tyrosine-kinase domain FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation differentiation and apoptosis
Medchemexpress LLC Glucagon-like peptide-1 receptor, human (HEK293), C-terminal Fc fusion | >95.0% | 5UG
Recombinant human glucagon-like peptide-1 receptor (GLP-1R) expressed in HEK293 cells and provided as a C-terminal human Fc fusion. Supplied as a lyophilized powder with high purity and low endotoxin for receptor binding, signaling studies, assay development, and antibody characterization. Intended for research use only.
- Recombinant human GLP-1 receptor expressed in HEK293 cells.
- C-terminal human Fc fusion for improved stability and detection.
- Lyophilized powder for long-term storage and transport.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Endotoxin level below 1 EU/μg suitable for many in vitro assays.
- Do not reconstitute below 100 μg/mL; freeze aliquots for extended storage.
Abcam Oxytocin, Reproductive hormone
Reproductive hormone
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC KGF/FGF-7 Human HE 2ug | 2ug
KGF/FGF-7 proteins coordinate embryonic development and regulate basic processes such as cell proliferation and differentiation Its critical role extends to normal branching morphogenesis KGF/FGF-7 Protein Human (HEK293 His) is the recombinant human-derived KGF/FGF-7 protein expressed by HEK293 with C-6 His labeled tag
Biolegend APC anti-beta Catenin 1 CTNNB1
APC anti-β Catenin 1 (CTNNB1) [12F7]; Isotype: Mouse IgG1, κ; Reactivity: Human, Mouse, Rat; Apps: ICFC; Size: 25 tests
Medchemexpress LLC Transforming growth factor beta 1 latency-associated peptide (human) | >95.0% | 2UG
Recombinant human transforming growth factor beta-1 (TGF-β1) latency-associated peptide (LAP). This tag-free protein contains a C33S mutation and corresponds to residues L30-R278 (249 amino acids). It is expressed in HEK293 cells, supplied in small vial sizes (2 μg), and tested at >95% purity by reducing SDS-PAGE. Predicted molecular mass is 28.5 kDa; SDS-PAGE typically shows a 20-45 kDa migration. Store frozen and handle per the supplier datasheet.
- Tag-free latency-associated peptide with defined C33S mutation
- Produced in HEK293 expression system for proper folding and post-translational modifications
- High purity (>95%) suitable for biochemical and cell-based assays
- Predicted molecular mass 28.5 kDa with expected SDS-PAGE profile of 20-45 kDa
- Provided in small aliquots for low-volume experiments
- Stable when aliquoted and stored at -20°C or -80°C
Medchemexpress LLC PDGF-BB protein, cynomolgus (HEK293, mFc, solution) | 98.0%
Recombinant PDGF-BB (cynomolgus) is an mFc-tagged growth factor produced in HEK293 cells and supplied as a 0.22 μm-filtered PBS solution for research use. The protein is highly purified (>95% by reducing SDS-PAGE), shows apparent molecular weight shifts due to glycosylation, and is shipped frozen with recommended low-temperature storage to preserve activity.
- mFc-tagged, mammalian-expressed protein suitable for receptor binding studies.
- Supplied as a sterile, filtered PBS solution, ready for use.
- High purity (>95%) as verified by reducing SDS-PAGE.
- Stored and shipped frozen to maintain stability and activity.
- Suitable for cell signaling, proliferation, and migration assays.
Medchemexpress LLC TGF beta 1/TGFB1 LAP 50ug | 50ug
The latency-associated peptide (LAP) of the transforming growth factor -1 (TGF- -1) proprotein is an important precursor that forms a complex with TGF- -1 LAP maintains the latent state of TGF- -1 during storage in the extracellular matrix ensuring controlled activation Interactions with environmental molecules such as LTBP1 LRRC32/GARP and LRRC33/NRROS intricately regulate TGF- -1 activation LRRC33/NRROS influences the activation of macrophages and microglia while LRRC32/GARP controls the activation of activated regulatory T cells Interactions with integrins induce conformational changes in LAP releasing active TGF- -1 LAP orchestrates controlled TGF- -1 activation in different physiological contexts Recombinant human TGF beta 1/TGFB1 LAP (biotinylated expressed in HEK293 cells Avi-tagged) is a biotinylated Avi-tagged LAP protein expressed in HEK293 cells[1][2]
Medchemexpress LLC HGF Human CHO 50ug
Recombinant human hepatocyte growth factor (HGF) expressed in CHO cells and supplied lyophilized for research use. The protein is >95% pure by reducing SDS-PAGE, exhibits validated biological activity in cell-based assays, and is offered in multiple microgram-scale sizes suitable for assay development and functional studies.
- High purity suitable for biochemical and cell-based assays.
- Expression in CHO cells preserves mammalian glycosylation.
- Validated biological activity (ED50 <10 ng/mL in 4MBr5 cells).
- Available in small, convenient package sizes for assay optimization.
- Lyophilized formulation for improved stability during storage and transport.
- Stable when aliquoted and stored at -20°C or -80°C for long-term use.
- Includes amino acid sequence and molecular weight information.
Medchemexpress LLC CA125 Human HEK293 5ug | 5ug
CA125 is a giant mucin-like glycoprotein expressed by epithelial ovarian neoplasms and cells which is an antigenic tumor marker CA125 provides a protective lubricating barrier against particles and infectious agents at mucosal surfaces CA125 binds to mesothelin (MSLN) mediates heterotypic cell adhesion contributing to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium CA125 is widely used for monitoring with ovarian epithelial cancer CA125 Protein Human (HEK293 His) is a recombinant human cancer antigen 125 (CA125) with a His label and is expressed in HEK293 cells[1][2][3][4][5][6][7]