Cell Culture Growth Factors and Hormones
CPC Scientific H-Gly-Pro-Glu-OH (trifluoroacetate salt) 250MG
This N-terminal tripeptide of IGF-I facilitated the in vitro release of acetylcholine with a several hundredfold higher potency (10-10 - 10-6 M) than intact IGF-I (4 ? 10-8 M), whereas truncated IGF-I lacking the tripeptide GPE, did not show any significant effect. This raises the possibility that GPE may be the active site of IGF-I. - Although the precise mode of action of GPE is still unknown, another study suggests that local administration of GPE is neuroprotective after brain HI injury via glial cells. In addition, systemic administration of GPE showed a more widespread neuroprotective effect. Therefore, GPE may represent a complementary pathway for central and systemic IGF-1's antiapoptotic effects.SEQUENCE: H-Gly-Pro-Glu-OH (trifluoroacetate salt)ONE-LETTER SEQUENCE: GPEMOLECULAR FORMULA: C12H19N3O6MOLECULAR WEIGHT: 301.3STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [32302-76-4]SYNONYMS: RESEARCH AREA: DiabetesREFERENCES:L.Nilsson-Hakansson et al., Neuro
CPC Scientific H-Gly-His-Lys-OH (acetate salt) 250MG
GHK possesses a high affinity for copper(II) ions, with which it spontaneously forms a complex (GHK-Cu). This growth-modulating plasma tripeptide, when added at nanomolar concentrations to a wide group of cultured systems, produces a disparate set of responses ranging from the stimulation of growth and differentiation to outright toxicity. It may function by facilitating copper uptake into cells. GHK-Cu accelerates wound healing. The palmitoylated peptide is marketed as a cosmetic ingredient under the trade name Biopeptide CL. CAS Number (net): 49557-75-7.SEQUENCE: H-Gly-His-Lys-OH (acetate salt)ONE-LETTER SEQUENCE: GHKMOLECULAR FORMULA: C14H24N6O4MOLECULAR WEIGHT: 340.38STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [72957-37-0]SYNONYMS: Prezatide, GHKRESEARCH AREA: MiscellaneousREFERENCES:S.-J.Lau and B.Sarkar, Biochem. J., 199, 649 (1981)J.-P.Laussac et al., Biochem. J., 209, 533 (1983)D.Downey et al., Surg. Forum, 36, 573 (1985)L.Pickart and S.Lovejoy, Me
Sigma Aldrich Fine Chemicals Biosciences Transforming Growth factor
Tgfb1 (transforming growth factor-1 human) is a 25kDa peptide encoded by the gene mapped to human chromosome 19q13.2. TGf-1 polypeptide is produced as a precursor with hydrophobic signal sequence pro-region and mature peptide. Cleavage of the precursor at tetrabasic cleavage site results in monomers of carboxy-terminal 112 amino acids. The biologically active form of Tgfb1 exists as a disulphide-linked homodimer. In mammals three isoforms of TGf- has been identified TGf-1 TGf-2 and TGf-3.
AdipoGen FGF-2 human rec
Protein. Human FGF-2 153aa. Source E. coli. Endotoxin content <0.1ng/µg protein. Lyophilized. Contains PBS. Purity >98% SDS-PAGE. FGF-2 plays an important role in the regulation of angiogenesis, cell survival, cell division, wound healing and tissue repair, embryonic development, cell differentiation and cell migration, neuronal function and neural degeneration. It functions as potent mitogen in vitro.
Sigma Aldrich Fine Chemicals Biosciences VEGf human Animal componen
VEGf (vascular endothelial growth factor) signals through the three receptors fms-like tyrosine kinase (flt-1) KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGf is a 38.2kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Cell Signaling Technology PathScanR RP Total Stat2 Sandwich ELISA Kit 50 Kit
PathScanR RP Total Stat2 Sandwich ELISA Kit 50 Kit
Cell Signaling Technology PathScanR Phospho-PDGF Receptor beta Tyr751 Sandwich ELISA Kit 5 Kit
PathScanR Phospho-PDGF Receptor beta Tyr751 Sandwich ELISA Kit 5 Kit
Biolegend APC anti-beta Catenin 1 CTNNB1
APC anti-β Catenin 1 (CTNNB1) [12F7]; Isotype: Mouse IgG1, κ; Reactivity: Human, Mouse, Rat; Apps: ICFC; Size: 25 tests
Medchemexpress LLC DDR1 protein, mouse (HEK293, His) | >95.0% | 100 UG
Recombinant mouse discoidin domain receptor 1 (DDR1) protein produced in HEK293 cells and supplied as a 0.22 μm filtered PBS solution with a C-terminal His tag. The protein is >95% pure by reducing SDS-PAGE, has an approximate molecular weight of 50-60 kDa, and is provided in a 100 μg format for research applications.
- Expressed in HEK293 for mammalian-like post-translational modifications.
- Supplied as a 0.22 μm filtered PBS solution ready for assays.
- C-terminal His tag facilitates purification and detection.
- High purity (>95%) suitable for biochemical and cell-based studies.
- Amino acid range corresponds to accession Q03146-2 (D20-T414) representing functional domains.
Medchemexpress LLC HY-P7074A 10ug Medchemexpress, IL-10 (CHO-expressed), Mouse CAS: Purity:>98%
Medchemexpress, HY-P7074A 10ug IL-10 (CHO-expressed), Mouse CAS: Recombinant Mouse Interleukin-10 (CHO-expressed) is a potent CHO cell derived anti-inflammatory cytokine results in increased immune-mediated demyelination in mice infected with a neurotropic coronavirus. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-P7066 10ug Medchemexpress, FGF-basic, Mouse CAS: Purity:>98%
Medchemexpress, HY-P7066 10ug FGF-basic, Mouse CAS: Recombinant Mouse Basic Fibroblast Growth Factor is a potent mitogen and chemoattractant for endothelial cells as well as fibroblasts. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Rab1b protein, human (HEK293, Fc) | 97.9% | 10 UG
Recombinant human RAB1B protein expressed in HEK293 cells and fused to an Fc tag. Supplied as purified protein suitable for biochemical and cell-based assays; reported molecular weight ~58 kDa and reported purity 97.9%.
- Recombinant human RAB1B expressed in HEK293 cells.
- Fc-tagged fusion to aid stability and detection.
- Purified protein with reported purity of 97.9%.
- Approximate molecular weight ~58 kDa.
- Suitable for biochemical and cell-based assays.