Cell Lines and Cell Cultures
Thermo Scientific™ GeneBLAzer™ RXRα-UAS-bla HEK 293T Cells
RXR alpha-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human retinoid X receptor-alpha (RXR alpha) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UASbla HEK 293T cell line.
Thermo Scientific™ CellSensor™ NFKB-bla Freestyle™ HEK293F Cell Line
Nuclear Factor kappaB (NFκB) signaling regulates genes involved in apoptosis, viral defense, cancer, inflammation, and autoimmune disease.
Thermo Scientific™ GeneBLAzer™ PPARδ-UAS-bla HEK 293T Cells
PPAR delta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Peroxisome Proliferator-Activated Receptor-delta (PPAR delta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ CellSensor™ SIE-bla HEK293T Cell Line
The CellSensor™ SIE-bla HEK 293T cell line contains a beta-lactamase reporter gene under control of the SIE response element stably integrated into HEK 293T cells.
Thermo Scientific™ GeneBLAzer™ GLP1R-CRE-bla CHO-K1 Cells
The GeneBLAzer™ GLP1R-CRE-bla CHO-K1 cells contain the human Glucagon-like Peptide 1 Receptor (GLP1R) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ LanthaScreen™ STAT5 TF-1 Cell Line
LanthaScreen™ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context.
Thermo Scientific™ LanthaScreen™ STAT3 GripTite™ Cell Line
The JAK/STAT3 signaling pathway is known to be activated by cytokines such as IL-6. In this pathway, binding of IL-6 to its cell-surface receptors results in the activation of JAKs, which in turn phosphoactivate STAT3 proteins at a specific tyrosine residue (Y705).
Thermo Scientific™ GeneBLAzer™ CRHR2-CRE-bla CHO-K1 Cells
GeneBLAzer™ CRHR2-CRE-bla CHO-K1 cells contain the human Corticotropin Releasing Factor Receptor 2 (CRHR2) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ CCKBR-NFAT-bla HEK293T Cells
GeneBLAzer™ CCKBR-NFAT-bla HEK293T cells contain the human Cholecystokinin Receptor B (CCKBR) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line.
Thermo Scientific™ GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 Cells
GeneBLAzer™ HTR2B-NFAT-bla CHO-K1 cells contain the human 5-hydroxytryptamine (serotonin) receptor 2B (HTR2B), stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ TrkC-NFAT-bla CHO-K1 Cell Line
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
Thermo Scientific™ GeneBLAzer™ ADRA1A-NFAT-bla CHO-K1 Cells
The GeneBLAzer™ ADRA1A-NFAT-bla CHO-K1 cells contain the human Adrenergic Alpha-1A Receptor (ADRA1A), (Accession No. NM_000680) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ LXRα-UAS-bla HEK 293T Cells
LXR alpha-UAS-bla HEK 293T 293 cells contain the ligand-binding domain (LBD) of the human Liver-X receptor-alpha(LXR alpha) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ CellSensor™ T-REx™ NICD CSL-bla HeLa Cell Line
This cell line is a clonal population isolated by flow cytometry. Addition of doxycycline to these cells allows for regulated NICD transcription factor expression and subsequent beta-lactamase expression.
Thermo Scientific™ LanthaScreen™ PRAS40 293E Cell Line
The PI3K/AKT pathway is activated by various stimuli (including insulin and IGF-1) and mediates signals for cell growth, cell survival, translation, and inhibition of apoptosis.