General Cell Lines and Cell Cultures
ATCC MSTO-211H; Mesothelioma; Human (Homo sapiens)
MSTO-211H is a cell line exhibiting fibroblast morphology that was isolated in 1985 from the lung of a 62-year-old, White male patient with biphasic mesothelioma. This cell line was deposited by G Bepler.
ATCC Bordetella pertussis; Strain: D420
Bordetella pertussis strain D420 is a bacterium isolated in 2002 from a human within the United States. This culture has applications in respiratory disease research.
Biochain Institute Inc Rectum Tumor Tissue Array - 64 Different Rectum tumors. Plus positive control and negative control, 2 slides/PK
BioChain's tissue arrays or tissue microarrays (TMAs) are a useful tool in biomarker research and drug target validation. It consists of paraffin blocks that are assembled in array fashion to allow multiplex histological analysis. BioChain's TMAs provide a valuable tool for analysis of protein, RNA, or DNA molecules in oncology, both the malignant and metastatic markers. TMAs can also be constructed with tissues from other diseases and species.
ATCC Primary Bronchial/Tracheal Epithelial Cells; COPD, Human
Primary bronchial/tracheal epithelial cells COPD are spindle-shaped cells isolated from the respiratory tract of a donor with COPD. The cells have an application in microbial (eg, viral, bacterial) infection and pathogenesis, airway inflammation and wound healing, asthma, pulmonary fibrosis, chronic obstructive pulmonary disease, chronic bronchitis, toxicology, and testing of pharmaceuticals.
Eurofins Discoverx GALR2 Gq Calcium Signaling Cell-Based Assay Kit (CHO-K1)
The GALR2 Gq Stable Cell Line Calcium Signaling Assay (CHO-K1) contains a stable clonal cell line used to measure GALR2 (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ATCC Staphylococcus aureus; subsp. aureus
Penicillin sensitive. Does not produce penicillinase. Usually lysed by phages 7, 47, 53, 54 and 77. According to the depositor, this item is resistant to 25 μg of tetracycline, but sensitive to 50 μg.
Eurofins Discoverx PathHunter CHO-K1 GPR157 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0414C2A)
The PathHunter GPR157 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR157 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR157 and EA-tagged β-Arrestin-2. Activation of GPR157 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. This is an orphan receptor without a known ligand. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PrecisION hKv1.2 Recombinant Stable Cell Line, 2 vials. (CYL3015)
The PrecisION hKv1.2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv1.2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv1.2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
ATCC Streptococcus pyogenes T1 genomic DNA
Genomic DNA isolated from Streptococcus pyogenes typing strain T1 (ATCC 12344). This whole-genome sequenced product can be used in PCR and other molecular biology applications.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Heart: Atrium (right), 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Heart: Auricula (left), 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Brain: Olfactory ( region), 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Frozen Tissue Section - Arteriosclerosis Artery and Matched Non-arteriosclerosis Artery, 2 x 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. The tissues are immediately put in liquid nitrogen after being excised, and then identified by a board-licensed pathologist. Patient demographic and disease related history data are available. BioChain's frozen tissue section line encompasses a large selection of tissue sections which are good for immunohistochemistry and in situ hybridization. The tissue sections are approximately 5-10 um thick.
Eurofins Discoverx PathHunter GLP1R Total GPCR Internalization U2OS Cell Line, 2 vials. (93-1075C3)
The PathHunter GLP1R Total GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of GLP1R via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged GLP1R and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the GLP1R receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.