General Cell Lines and Cell Cultures
Eurofins Discoverx GPR17 Gq Calcium Signaling Cell-Based Assay Kit (CHO-K1)
The GPR17 Gq Stable Cell Line Calcium Signaling Assay (CHO-K1) contains a stable clonal cell line used to measure GPR17 (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cell Systems Corporation 5 Vials Primary Human Coronary Artery Endothelial Cells - Same Lot (ACBRI377V5)
Boost your research program with 5 identical vials of passage 3 Primary Human Coronary Artery Endothelial Cells while saving ~ 20% on purchase. Isolated from normal human coronary artery without positive control antibody labels. Each vial contains ~1 x 10^6 cells with 85-92% viability under ideal conditions. They are available at Passage 3 (<12 cumulative population doublings) and will initiate a Passage 4 cell culture in a 75 cm2 flask. Each vial of cells is shipped with Bac-Off (antibiotic) and CultureBoost (animal derived growth factors) at no additional cost. You can enhance consistency in your research program with reserved lots. Need vials in bulk? Contact your Fisher Scientific Sales representative for tailored quotes. Tight Deadline? Our cells are available for next day delivery after the purchase order is received. Accelerate Your Research! Try our Attachment Factor (4Z0-201, 4Z0-210) – innovative 5 seconds plating solution for all surfaces.
Eurofins Discoverx MRGPRX1 Gq Calcium Signaling Cell-Based Assay Kit (RBL-2H3)
The MRGPRX1 Gq Stable Cell Line Calcium Signaling Assay (RBL-2H3) contains a stable clonal cell line used to measure MRGPRX1 (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Biochain Institute Inc Multiple Species Frozen Tissue Array - Brain, 1 slide/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. Multiple Species Frozen Tissue Array is designed for testing the species reactivity of antibodies. This array can bring very important information of antibodies in immunohistochemistry studies. Besides, frozen tissues are always the solution in case antibodies can not recognize their antigens in paraffin embedded tissues. The Multiple Species frozen tissue array can also enable you to study expression of genes or proteins of interest among different animals. BioChain's Frozen Tissue Arrays are manufactured using high-quality tissues. Each section is approximately 5 um thick. H.E. staining and immunostaining using beta-actin antibody ensure quality. Frozen tissue array is ideal for rapid cellular localization of RNA and protein expression.
Biochain Institute Inc Matched Pair - Frozen Tissue Section - Human Primary Tumor and Normal (PP): Colon, 5 x2 slides /PK
BioChain's tissue products are based on the sample repository network established following the ethical standard and IRB-approved procedures. During the collection, the excised tissues are immediately put into liquid nitrogen and then identified by a board-licensed pathologist. Patient demographic and disease related history data are available. Human frozen tissue section matched pair products include: Primary Pair (PP), Primary and Metastatic Pair (PM). PP consists of frozen tissue sections of primary tumor and its adjacent normal tissue; PM consists of frozen tissue sections of primary tumor and corresponding metastatic tumor. Frozen tissue sections in each pair are prepared from the same donor. This product line is ideal for localization of tumor-specific genes and tumor metastatic genes.
Eurofins Discoverx PathHunter Rat PROKR1 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Rat PROKR1 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure rPROKR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter CHO-K1 MC4R Gs Cell Line, 2 vials. (95-0050C2)
The cAMP Hunter MC4R Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. α-melanocyte stimulating hormone) based activation of MC4R GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type MC4R, a naturally Gs coupled GPCR. Upon activation of MC4R, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen C5aR Anaphylotoxin Receptor Membrane Preparation, 1 vial. (HTS017M)
The ChemiScreen C5aR Anaphylotoxin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of C5AR1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx ChemiScreen NMU1 Neuromedin U Receptor Stable Cell Line, 2 vials. (HTS062C)
The ChemiScreen nMU1 Neuromedin U Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. Neuromedin U) based activation of nMU1R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses nMU1R alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of nMU1R, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Biochain Institute Inc Frozen Tissue Section - Multiple Sclerosis Disease: Brain: Corpus Callosum, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
ATCC Pfizer Pneumococcal polysaccharide powder Type 70 (d33F) 200mg
Purified pneumococcal polysaccharide type 33F is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 33F can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Genscript Corporation HVEM-Fc Human
Herpes Virus Entry Mediator (HVEM) is a transmembrane protein that is the receptor for TNFSF14 (also known as LIGHT) and is therefore referred to asTNFRSF14 HVEM is expressed broadly on immune cells such as T cells natural killer (NK) cells and monocytes The interaction of 3 molecules of LIGHT with three molecules of HVEM forms a hexameric complex that leads to the recruitment and retention of effector cells and activates NK cells to produce large amounts of IFN- and GM-CSF In addition to the canonical binding partner LIGHT HVEM can also bind to the inhibitory signaling protein B- and T- lymphocyte attenuator (BTLA) which suppresses immune responses Therefore the HVEM network plays an important role in regulating immunity and the behavior of lymphocytes