General Cell Lines and Cell Cultures
Biotium PAX8 (Renal Cell Marker)(PAX8/2774R), CF568 conjugate, 0.1mg/mL
Recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors. Primary antibodies are available purified, or with a
Eurofins Discoverx FFAR2 (GPR43) Gq Calcium Signaling Cell-Based Assay Kit (CHO-K1)
The FFAR2 (GPR43) Gq Stable Cell Line Calcium Signaling Assay (CHO-K1) contains a stable clonal cell line used to measure FFAR2 (GPR43) (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Biotium Ki-67 (Proliferating Cell Marker) (MKI67/2462), Biotin conjugate, 0.1mg/mL
Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.Primary antibodies are available purified, or with a selection of
Biotium MUC16 / CA125 (Ovarian Carcinoma Marker)(MUC16/1860), Biotin conjugate, 0.1mg/mL
The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker
Eurofins Discoverx mGlu5 (GRM5) Gq Calcium Signaling Cell-Based Assay Kit (U2OS)
The mGlu5 (GRM5) Gq Stable Cell Line Calcium Signaling Assay (U2OS) contains a stable clonal cell line used to measure GRM5 (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Cyno IL-8 (CXCR2) β-Arrestin Cell-Based Assay Kit (HEK 293)
The PathHunter Cyno IL-8 (CXCR2) β-Arrestin Stable Cell Line Assay (HEK 293) contains a stable clonal cell line used to measure CXCR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Bioworld Frozen Storage Buffer for Competent Cells, 125 mL
This Frozen Storage Buffer is used for frozen storage of competent cells. It contains 10mM potassium acetate, 10mM calcium chloride (CaCl2.2H2O), 100mM potassium chloride, 45 mM manganese chloride (MnCl2.4H2O), 3mM cobalt chloride hexahydrate and 10% glycerol. The pH of complete solution is adjusted to pH 6.4 with HCl and autoclaved.Warning: For laboratory use only.Not fit for agricultural, household, clinical use or human consumption. Appearance: LiquidPH Value: 6.4
Biotium Ki-67 (Proliferating Cell Marker) (MKI67/2462), CF647 conjugate, 0.1mg/mL
Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.Primary antibodies are available purified, or with a selection of