General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter MC3R Total Internalization U2OS Cell Line, 2 vials. (93-0837C3)
The PathHunter MC3R Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of MC3R via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged MC3R and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the MC3R receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PrecisION hNav1.2 Recombinant Stable Cell Line, 2 vials. (CYL3023)
The PrecisION hNav1.2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Nav1.2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Nav1.2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Amsbio LLC Human HT-29 / Luciferase (Firefly) Stable Cell Line
Human HT-29 / Luciferase (Firefly) Stable Cell Line
ATCC Primary Uterine; Smooth Muscle Cells; Normal, Human
Primary uterine smooth muscle cells are elongated myocytes isolated from the uterus of a donor and can be used in female reproductive biology, drug testing, and oncology.
ATCC pTR-UF-11 plasmid; in E. coli
pTR-UF11 is an adeno-associated virus-based plasmid vector containing a CMV IE enhancer and chicken Beta-actin promoter driving the hGFP gene. It is distributed in Escherichia coli.
Biochain Institute Inc Frozen Tissue Array - Human Tumor and Normal Tissue, Multi-tissue I, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. The tissues are immediately put in liquid nitrogen after being excised, and then identified by a board-licensed pathologist. Patient demographic and disease related history data are available. BioChain's human tumor and normal multiple frozen tissue arrays are designed for studying tumor tissue specific cellular localization of genes or proteins of interest in different human tissues. 14 tumors and 14 correspondant normal tissues are mounted on a positively charged glass slide.
Genscript Corporation CHO-K1/MC2/G15 Stable Cell Li
The melanocortin receptor 2 MC2 receptor is G sub s /sub -coupled GPCRs expressed in zona fasciculata of the adrenal cortex placental and stimulates production of cortisol MC2 is a member of the rhodopsin family of 7-transmembrane and it s also known as the ACTH receptor or corticotropin receptor because it is specific for ACTH alone Activation of the MC2 receptor initiates a cascade of events affecting multiple steps in corticoid steroidogenesis Mutations in MC2 may result in familial glucocorticoid deficiency a group of autosomal recessive disorders characterized by resistance to ACTH
Miltenyi Biotec, Inc. CD270 (HVEM)-PE, human
Identification and enumeration of CD270 (HVEM)+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
Eurofins Discoverx ChemiScreen CCR1 Chemokine Receptor Membrane Preparation, 1 vial. (HTS005M)
The ChemiScreen CCR1 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CCR1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Cell Applications Inc Proliferating Rat Epidermal Keratinocytes (REK), Adult
Proliferating Rat Epidermal Keratinocytes (REK), Adult
ATCC Mesenchymal Stem Cell Basal Medium, 485mL
Mesenchymal Stem Cell Basal Medium for Adipose, Umbilical, and Bone Marrow-derived MSCs is a sterile, phenol red-free, liquid tissue culture medium intended for use as one component in a complete ATCC Primary Cell Solutions system. This low serum (2% FBS) system supports mesenchymal stem cells derived from various normal human tissues lipoaspirates, and umbilical cord. Mesenchymal Stem Cell Basal Medium for Adipose, Umbilical, and Bone Marrow-derived MSCs contains essential and non-essential amino acids, vitamins, other organic compounds, trace minerals, and inorganic salts. To support the proliferation and plating efficiency of various adult stem cells, Mesenchymal Stem Cell Basal Medium with the appropriate cell-specific growth kit. When using this complete media system, the growth of undifferentiated mesenchymal stem cells does not need feeder layers, extracellular matrix proteins, or other substrates.
Eurofins Discoverx mGlu5 (GRM5) Gq Calcium Signaling Cell-Based Assay Kit (U2OS)
The mGlu5 (GRM5) Gq Stable Cell Line Calcium Signaling Assay (U2OS) contains a stable clonal cell line used to measure GRM5 (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ATCC MCF7-Luc2; Breast Adenocarcinoma; Human (Homo sapiens)
For-profit organizations: For every order of this item, you must provide a signed Material Transfer Agreement Addendum for Screening Application. We cannot ship this item until we receive this addendum. The person signing the addendum as the principal investigator must match the end user as listed on the applicable sales order for the item.Email the signed addendum to SalesPermits@atcc.org with a reference to both your account and sales order numbers. Once received, your addendum will be reviewed, and this item will be released for shipment if all requirements are met. Additional fees may apply if this product is being used for a screening use (ATCC ACS-2103F), and these fees will be applied after your order is confirmed. If you need assistance with your order, please contact our Customer Care team.
ATCC Escherichia coli; Quantitative DNA
Quantitative Genomic DNA from Escherichia coli strain 2003-3014 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC Merck Pneumococcal polysaccharide powder Type 57 (d19A) 2mg
Purified pneumococcal polysaccharides are manufactured by Merck & Company for small quantity distribution by ATCC. The pneumococcal powders include those types which are components of the current 23-valent vaccine against Streptococcus pneumoniae.Each of the polysaccharide antigens used in the polyvalent vaccine is extracted and purified separately. These vaccine products can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.