General Cell Lines and Cell Cultures
Vector Biolabs Arrestin, beta 1 Adenovirus (Ad-Arrestin-1(beta))
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions.
ATCC Candida albicans; Type II
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Brain: Cerebellum (right), 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
ATCC L1210; Leukemia; Mouse (Mus musculus)
L1210 is a cell line exhibiting lymphoblast morphology that was isolated from the skin of an eight-month-old, female mouse with lymphocytic leukemia, developed after skin paintings with 0.2% methylcholanthrene in ether. This cell line was deposited by EM Jensen and can be used in immune system disorder research.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Blood Vessel: Artery, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx ChemiScreen MCH2 Melanin-concentrating Hormone Receptor Stable Cell Line, 2 vials. (HTS026C)
The ChemiScreen MCH2 Melanin-concentrating Hormone Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. MCH) based activation of MCHR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MCHR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of MCHR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Corynebacterium striatum; 6 x 0.3mL
ATCC BAA-1293-MINI-PACK™ consists of 6 ready-to-use vials of ATCC BAA-1293™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.