General Cell Lines and Cell Cultures
ATCC L-M; Connective Tissue; Mouse (Mus musculus)
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
ATCC Borrelia burgdorferi; Quantitative DNA
Quantitative genomic DNA from Borrelia burgdorferi strain B31 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load and for other molecular biology applications.
Eurofins Discoverx Ready-to-Assay NK2 Tachykinin Receptor Frozen Cells, 2 Vials of Cells. (HTS144RTA)
The Ready-to-Assay NK2 Tachykinin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. tachykinins) based activation of TACR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TACR2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of TACR2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PathHunter U2OS FLT3 Activity Assay, 2 vials. (93-0901C3)
The PathHunter FLT3 RTK Activity cell line is a stable, engineered cell line for use in studying small molecule drug candidates targeting RTKs. This cell line enables assessment of RTK activity via detection of resulting FLT3 phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged FLT3 to the extracellular ligand binding domain of EGFR alongside an EA-tagged SH2 domain protein. Upon ligand induced receptor activation, cross-phosphorylation of the receptor leads to SH2-EA recruitment and production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Eurofins Discoverx Ready-to-Assay 5-HT4B Serotonin Receptor Frozen Cells, 2 Vials of Cells. (HTS110RTA)
The Ready-to-Assay 5-HT4B Serotonin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. serotonin/5-HT) based activation of HTR4B GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses HTR4B alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of HTR4B, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Debaryomyces hansenii; genomic DNA
DESCRIPTION: Genomic DNA isolated from Debaromyces hansenii CBS 767. This fungal strain is also available as ATCC Catalog No.: 36239™.
ATCC Eubacterium nodatum
Eubacterium nodatum strain VPI D6 A-5 is a bacterial type strain that was isolated from the subgingival region of a mouth. This strain is propagated anaerobically.
Eurofins Discoverx ChemiScreen 5-HT6 Serotonin Receptor Stable Cell Line, 2 vials. (HTS111C)
The ChemiScreen 5-HT6 Serotonin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin/5-HT) based activation of HTR6 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses HTR6 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of HTR6, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen CXCR4 Receptor Stable Cell Line, 2 vials. (HTS004C)
The ChemiScreen CXCR4 Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL12/SDF-1α) based activation of CXCR4 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CXCR4 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CXCR4, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen NTR1 Neurotensin Receptor Stable Cell Line, 2 vials. (HTS034C)
The ChemiScreen NTR1 Neurotensin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. neurotensin) based activation of NTSR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses NTSR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of NTSR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Salmonella enterica; subspecies enterica; serovar Enteritidis; Strain: SAP18-0432
Salmonella enterica subsp. enterica serovar Enteritidis strain SAP18-0432 was isolated in the United States from a human. This whole-genome sequenced bacterium was part of the 2018 PulseNet-GenomeTrakr joint proficiency test exercise. This strain has applications in infectious disease research and zoonotic disease research.
Eurofins Discoverx BRS3 Gq Calcium Signaling Cell-Based Assay Kit (CHO-K1)
The BRS3 Gq Stable Cell Line Calcium Signaling Assay (CHO-K1) contains a stable clonal cell line used to measure BRS3 (GPCR) activation via an increase in intracellular calcium. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ATCC Cryptococcus gattii; A6MR38
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.