General Cell Lines and Cell Cultures
Eurofins Discoverx cAMP Hunter CHO-K1 mRXFP1 Gs Cell Line, 2 vials. (95-0180C2)
The cAMP Hunter mRXFP1 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. relaxin-2) based activation of mRXFP1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type mRXFP1, a naturally Gs coupled GPCR. Upon activation of mRXFP1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx cAMP Hunter 1321N1 CALCR-RAMP3 Gs Cell Line, 2 vials. (95-0166C6)
The cAMP Hunter CALCR-RAMP3 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. calcitonin) based activation of CALCR GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CALCR, a naturally Gs coupled GPCR, alongside modulator protein RAMP3. Upon activation of CALCR-RAMP3, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. This product expresses CALCR alongside the receptor modifying protein RAMP3, which increases activity of the CALCR receptor For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx cAMP Hunter U2OS HTR7B Gs Cell Line, 2 vials. (95-0156C3)
The cAMP Hunter HTR7B Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin/5-HT) based activation of HTR7B GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type HTR7B, a naturally Gs coupled GPCR. Upon activation of HTR7B, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Clostridioides difficile Strain 4111 genomic DNA
Genomic DNA isolated from Clostridioides difficile Strain 4111. This bacterial strain is also available as ATCC Catalog No. BAA-1871™.
ATCC Methylorubrum extorquens; (u s patent 5,302,525)
Methylorubrum extorquens strain 58 is a bacterium that was isolated from oil-contaminated soil. It is cited to produce poly-beta-hydroxybutyric acid polymers.
ATCC Mycobacterium tuberculosis; variant bovis BCG
The depositor states that this strain exhibits low virulence in mice and guinea pigs.
ATCC Olsenella uli
Olsenella uli strain VPI D76D-27C [NCFB 2895] is a anaerobic bacterial type strain that was isolated from the gingival crevice of a human.
ATCC M059J; Malignant Glioblastoma; Human (Homo sapiens)
M059J is a glial cell isolated from the brain of a 33-year-old, male patient with malignant glioblastoma. These cell lines provide helpful model systems in which to study the role of DNA protein kinase in cellular and molecular processes involving DNA damage recognition and repair. It can be used in neuroscience research.
Revvity Health Sciences Inc cAMPZen Frozen Human Adenosine A2α, HEK293 Cells
cAMPZen Frozen Human Adenosine A2α, HEK293 Cells
ATCC Escherichia coli; O145-Nanoluc
A kit containing reporter-labeled Escherichia coli designed to distinguish control strain cross-contamination from true contamination in test samples. This product is appropriate for use as a positive control in quality control assays for E. coli.