General Cell Lines and Cell Cultures
Eurofins Discoverx ChemiScreen EP1 Prostanoid Receptor Stable Cell Line, 2 vials. (HTS099C)
The ChemiScreen EP1 Prostanoid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin E2) based activation of PTGER1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGER1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of PTGER1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Biolegend Ultra-LEAFTM Purified anti-mou
Ultra-LEAF™ Purified anti-mouse/human CD351 (Fc α/µ receptor) [TX61]; Isotype: Mouse IgG1, κ; Reactivity: Mouse, Human; Apps: FC, Block; Size: 1 mg
Brainxell Inc Cortical Glutamatergic Neurons (Human iPSC-Derived, Male Line, GFP Reporter, 2M)
Cortical glutamatergic neurons derived from iPSC line WC-30, male. Contents: 1 vial of ≥ 2x10^6 viable cryopreserved cells. Ubiquitously expressing eGFP. Marker Expression: Cortical Glutamatergic Neurons (BX-0300) have high neuronal purity (>80%) and comprise predominantly excitatory neurons. Labeling with the pan-neuronal marker MAP2 (red) highlights the neuronal purity of these cells. Labeling with the glutamatergic-specific marker FOXP2 indicates the overwhelming presence of glutamatergic neurons. Function: Cortical Glutamatergic Neurons exhibit pronounced electrophysiological activity after two weeks in culture, as demonstrated by multi-electrode array (MEA) recordings. Related diseases: Alzheimer's & Huntington's Disease. Primary neurotransmitter released: Glutamate
ATCC Quantitative Genomic DNA from; Aspergillus terreus; Strain: MF4845
Quantitative Genomic DNA from Aspergillus terreus strain MF4845 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine fungal load.
ATCC Saccharomyces cerevisiae; YPH499
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
ATCC NCI-H1299; Lung Carcinoma; Human (Homo sapiens)
NCI-H1299 is an epithelial-like cell that was isolated from the lung of a White, 43-year-old, male patient with carcinoma. This cell line was deposited by AF Gazdar and JD Minna and can be used in cancer and immuno-oncology research.
Montana Molecular Human Kappa Opioid Receptor (KOR, OPRK, OPRK1) Big Sky BacMam, 15mL
Human Kappa Opioid receptor packaged in Big Sky BacMam for mammalian cell expression. BacMam packaging provides efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in primary or iPSC-derived cells. BacMam expression is easily titrateable to suit your experimental needs.
Amsbio LLC eLuCidate™ HeLa, TLR4/IL-8 Reporter Cell Line
eLuCidate™ HeLa TLR4/IL-8 Reporter Cell Line
Eurofins Discoverx cAMP Hunter CHO-K1 GPR109A Gi Cell Line, 2 vials. (95-0122C2)
The cAMP Hunter GPR109A Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. nicotinic acid) based activation of GPR109A GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GPR109A, a naturally Gi/Go coupled GPCR. Upon activation of GPR109A, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Lacticaseibacillus paracasei; subsp. paracasei
Lacticaseibacillus paracasei subsp. paracasei is a whole-genome sequenced bacterium that was isolated from an oral cavity.
Amsbio LLC Luciferase & GFP Expression Hela cells (Puro)
Luciferase & GFP Expression Hela cells (Puro)