General Cell Lines and Cell Cultures
Lonza Walkersville AGM Astrocyte Growth Medium BulletKit
Clonetics AGM Astrocyte Growth Medium has been developed to support the growth of primary astrocytes. Media products are provided as convenient BulletKits which contain basal medium and necessary growth factors for cell culture.Media are supplied in several formats:Basal Medium - Contains no growth factors cytokines, or supplementsSingleQuots - Growth factors, cytokines, and supplements (basel media not included)BulletKits- Basal media and SingleQuots Kit packaged togetherContent:1 x ABM Basal Medium (CC-3187), 500 mL1 x AGM SingleQuots Supplement Pack (CC-4123) containing:1 x Bottle FBS, 15.0 mL1 x Bottle L-Glutamine, 5.00 mL1 x Vial GA-1000, 0.50 mL1 x Vial Ascorbic Acid, 0.50 mL1 x Vial HEGF, 0.50 mL1 x Vial Insulin, 1.25 mL
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Diaphragm, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ABclonal Technology CHRM1 Rabbit pAb
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Biochain Institute Inc Paraffin Tissue Section - Human Lung Tumor, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Genscript Corporation CHO-K1/human CD32A 131His Stab
Recombinant CHO-K1 cells stably overexpress human immunoglobulin gamma Fc region receptor II-a (Fc RIIa/CD32A 131His) on the surface The surface expression of CD32A 131His is validated by FACS analysis This stable cell line product is designed for measuring binding affinity and stability of Fc region of antibodies and Fc fusion proteins or antibody based biologics binding with CD32A 131His GenScript also offers CD32A 131Arg stable cell line (Cat No M00887) for Fc RIIa polymorphism study
Genscript Corporation CD47 Human
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRP ) CD-47 acts as a don t eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers
Eurofins Discoverx PathHunter U2OS AVPR1A β-Arrestin Cell Line, 2 vials. (93-0587C3)
The PathHunter AVPR1A cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. vasopressin) based activation of AVPR1A GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged AVPR1A and EA-tagged β-Arrestin-2. Activation of AVPR1A stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Innovative Research Inc Pooled Human Saliva 250ml
Pooled Human Saliva from Innovative Research is collected fresh from two or more donors, pooled, and stored frozen. Produced in the salivary glands, human saliva is 99.5% water, but contains many important substances including electrolytes, mucus, antibacterial compounds, and various enzymes.
Genscript Corporation CHO-K1/CB2 Stable Cell Line
The Cannabinoid receptor 2 (CNR2) is a G sub i/o /sub -coupled GPCR expressed in spleen tonsils bone marrow and peripheral blood leukocytes There is one report that cannabinoid-induced inhibition of helper T cell activation is lost in macrophages obtained from CNR2 knockout mice CNR2 is a potential therapeutic target in the treatment of various disease conditions such as pain multiple sclerosis vascular disease Parkinson s disease and other central nerve system disorders
Heat-inactivated SARS-CoV-2 strain 2019-nCoV/USA-WA1/2020 (ATCC VR-1986HK™)
Heat-inactivated SARS-CoV-2 strain 2019-nCoV/USA-WA1/2020 (ATCC VR-1986HK™) is a whole-genome sequenced preparation inactivated by heating to 65°C for 30 minutes. Originally isolated from a confirmed human case in Washington state, it is intended for use in molecular assays or as a process control (eg, viral RNA extraction through qPCR amplification process), and it can also be used to make a dilution series to estimate level of detection. Each vial contains ~0.25 mL of clarified cell lysate and supernatant from infected Vero E6 cells.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Vagina, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Biochain Institute Inc Paraffin Tissue Section - Human Breast Tumor: Lobular carcinoma, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Genscript Corporation CHO-K1/ADORA3/G15 Stable Cell
Extracellular adenosine mediates a multitude of biological effects including wakefulness antiarrythmia bronchoconstriction and response to ischemia and oxidative stress A family of four G-protein coupled adrenoceptors A1 A2A A2B and A3 is responsible for these effects A3 which couples to G sub i/o /sub is expressed in a wide range of human tissues but most predominantly in the lung and liver Recent animal model studies have shown that A3 receptors play important roles in brain ischemia immunosuppresion and bronchospasm A3 receptor agonists and/or agonists may have important clinical value in the treatment of asthma and inflammation Mice lacking A3 receptors display reduced mast cell degranulation and bronchoconstriction in response to adenosine
Cell Biolabs Inc Platinum-E Retroviral Packaging Cell Line, Ecotropic
The Platinum-E (Plat-E) Cell Line, a potent retrovirus packaging cell line based on the 293T cell line, was generated using novel packaging constructs with an EF1a promoter to ensure longer stability and high-yield retroviral structure protein expression. Plat-E cells stably express the gag, pol, and ecotropic envelope genes, allowing retroviral packaging with a single plasmid transfection: a cloning vector containing the gene of interest. Plat-E cells can be kept in good condition in for at least 4 months in the presence of drug selection, and can produce retroviruses with an average titer of 1 x 10^7 infectious units/mL by transient transfection. In addition, replication competent retroviruses are virtually nonexistent because only coding sequences of viral structural genes are used, avoiding unnecessary retroviral sequences. The resulting ecotropic virus can readily infect mouse or rat cells, but not cells of other species. FOR SALE TO ACADEMIC, GOVERNMENT AND NON-PROFIT LABS ONLY.
Eurofins Discoverx ChemiScreen LPA2 Lysophospholipid Receptor Stable Cell Line, 2 vials. (HTS207C)
The ChemiScreen LPA2 Lysophospholipid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. LPA) based activation of LPAR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses LPAR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of LPAR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.