Plasma is the liquid part of the blood and lymphatic fluid which makes up about half of its volume. Plasma is devoid of cells and unlike serum has not clotted. Some of the more common proteins found in plasma are albumin and prealbumin alpha1-acid glycoprotein transferrin lipoproteins (HDL LDL and VLDL) immunoglobulins complement proteins and coagulation proteins (thrombin plasminogin and fibrinogen). Citrated plasma contains citrate (3.8% trisodium citrate) as an anticoagulant.Plasma contains a variety of proteins with diverse functions. The primary functions of the plasma proteins include the maintenance of colloid osmotic pressure pH and electrolyte balance the transport of metal ions fatty acids steroids hormones and drugs to various organs of the body use as a source for amino acids for tissue nourishment hemostasis and the prevention of thrombosis the regulation of cellular activity and function through hormone signaling and defense against invasion through the