Sera
Cayman Chemical 3- 4-PyrIdylIndole 50mg
A ROCK1 inhibitor (IC50 = 25 µM) that promotes cell spreading, inhibits membrane blebbing, and induces dissolution of actin stress fibers in a wound healing assay; also inhibits ROCK2 and PRK2 with similar potency, while inhibiting MSK-1 and PKA with relatively weaker potency
American Research Products Inc Rat Complement fragment 5 C5
Rat Complement fragment 5 C5 ELISA Kit from CUSABIO Detection Range 9 38 ng/mL-600 ng/mL Sensitivity 2 34 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Cayman Chemical SB-271046hydrochlorIde 50mg
A selective, orally-available antagonist of the 5-HT6 receptor (pKi = 9.02-8.92); produces a significant increase in extracellular levels of glutamate and aspartate within the frontal cortex; used to evaluate the role of 5-HT6 in learning and memory
Cayman Chemical BIs 2CLOroIsopropyl ethR 100mg
A byproduct in the synthesis of ethylene and propylene glycol; has been found in municipal drinking water in the United States and waterways in the Netherlands where it is considered a POP; mutagenic in the S. typhimurium strains TA 1535 and TA 100
Cayman Chemical snGlycerol3phosphatecycl 100mg
A lipid biosynthesis intermediate; functions in oxidative phosphorylation as part of the glycerophosphate shuttle; used in synthetic biology, studies of reactive oxygen species, and to measure phosphatidic acid in cell cultures; vital for systemic acquired resistance in plants; levels in saliva are altered in patients with Alzheimer’s, dementia, and Lewy body disease
Cayman Chemical BuformInhydrochlorIde 100mg
A biguanide that exhibits antihyperglycemic activity by increasing glucose utilization and inhibiting hepatic gluconeogenesis; inhibits the mitochondrial respiratory complex I and the mitochondrial ATP synthase; disrupts the unfolded protein response transcription program during glucose deprivation, inducing cell death in glucose-deprived tumor cells
Cayman Chemical 1R 9SHydrastIn 50mg
An inhibitor of dopamine biosynthesis (IC50 = 20.7 µM in PC12 cells); inhibits tyrosine hydroxylase activity; inhibits dopamine release in the presence of a high extracellular K+ level (IC50 = 66.5 µM); inhibits L-type and caffeine-activated store-operated Ca2+ channels; prevents Ca2+ leakage from intracellular stores
Cayman Chemical DesloratdIn 100mg
A histamine H1 receptor antagonist (Ki = 0.97 nM) and an active metabolite of loratadine; inhibits calcium flow in neurons and glia in vitro (IC50s = 9.177 and 0.3185 µM, respectively) in a 5-HT2A receptor-dependent manner; reduces ovalbumin-induced sneezing, nose rubbing, eye watering, and congestion in ovalbumin-sensitized guinea pigs at 10 mg/kg; increases the clearance of amyloid-β by microglia and reverses learning and memory deficits in the Morris water maze in the APP/PS1 mouse model of Alzheimer’s disease at 20 mg/kg per day
Cayman Chemical PF-562271besylate 50mg
An ATP-competitive, reversible inhibitor of FAK (IC50 = 1.5 nM) and PYK2 (IC50 = 14 nM); inhibits FAK phosphorylation (EC50 = 93 ng/ml) in glioblastoma-bearing mice and has been shown to regress tumors in multiple xenograft models
Cusabio Technology LLC Horse LeptinLEP ELISA kit
The Horse Leptin (LEP) ELISA Kit is designed to detect and quantify LEP concentrations in equine serum plasma and tissue homogenates with high sensitivity and precision This kit employs a competitive ELISA format enabling reliable quantitative measurement within a dynamic range of 3 12 pg/mL to 200 pg/mL and achieves a lower detection limit of 0 78 pg/mL The assay requires a sample volume of 50-100 L and can be completed within 1-5 hours with absorbance readings taken at 450 nm Suitable for both research and diagnostic applications it provides a standardized user-friendly method to assess leptin levels in horses ensuring consistent reproducibility across experimental or clinical settings
Cayman Chemical CarbetapentncItrate 100mg
A σ1 receptor agonist (Ki = 10.4 nM); inhibits citric acid-induced cough in guinea pigs from 1-5 mg/kg; reduces the number of seizures, mortality, and hippocampal neuronal cell death in a rat model of kainate-induced seizures at 12.5 and 25 mg/kg