An inhibitor of glucosylceramide synthase; inhibits glucosylceramide synthase by 70, 41, and 62% in MDCK cell homogenates, mouse liver microsomes, and mouse brain homogenates, respectively, at 20 µM; inhibits sphingomyelin synthase activity in P. falciparum-infected erythrocytes and inhibits growth of P. falciparum (IC50 = 0.85 µM)