Sera
Cayman Chemical ThIophnate-methyl 100mg
A carbamate fungicide; active against a variety of fungi (EC50s = <1 to 1-10 µM); induces hepatotoxicity and increases hepatic ROS in zebrafish larvae and adults at 12.5 and 25 mg/L
Cayman Chemical TerlIpresInacetate 50mg
A prodrug form of lysipressin; a partial agonist of the vasopressin V1A receptor (Ki = 0.85 µM); an agonist of vasopressin V1B and V2 receptors (Kis = 1.11 and 1.58 µM, respectively); increases MAP and decreases mortality in a rat model of uncontrolled hemorrhagic shock at 15 UG/kg; improves vascular reactivity and increases survival time in a rat model of cecal ligation and puncture-induced septic shock and a rabbit model of LPS-induced septic shock at 2.6 UG/kg per hour in combination with norepinephrine; increases MAP in a rat model of liver cirrhosis
Cayman Chemical NMethylNnItrosopIperazIn 50mg
A potential impurity in various pharmaceutical preparations
Cayman Chemical LPhenylephrInhydroCLOrId 100mg
An adrenergic α1A receptor agonist (Ki = 1.4 µM) that demonstrates selectivity against the α1B and α1C receptor subtypes (Kis = 23.9 and 47.8 µM, respectively); frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents
Cayman Chemical Maytnsnol 50mg
An ansa macrolide; inhibits polymerization and induces depolymerization of bovine brain tubulin (EC50s = 12 and 43 µM, respectively); inhibits sea urchin egg mitosis at 10 µM and decreases proliferation of KB nasopharyngeal cancer cells (EC50 = 0.19 UG/ml)
Sigma Aldrich Fine Chemicals Biosciences Human serum cystatin C ERM1EA
Certified for cystatin C in human serum. ERM-DA471IfCC cert ERM-DA471IfCC reportERM-DA471IfCC origin
Cayman Chemical trns-nrolIdol 100mg
A sesquiterpene with diverse biological activities; inhibits the growth of S. aureus, B. subtilis, E. coli, and S. cerevisiae; reduces viability of CaCo-2 adenocarcinoma cells (IC50 = 28.7 mg/L); insecticidal against A. aegypti (LC50 = 9 mg/L)
Cayman Chemical 7ahydroxy3oxo5Choln24 50mg
A metabolite of chenodeoxycholic acid; formed from chenodeoxycholic acid primarily by CYP3A4 but also by CYP3A5 and other P450 enzymes at lower rates
Cayman Chemical LuteolosIde 50mg
A flavanoid with diverse biological activities; reduces LDH and caspase-3 activities and production of ROS and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury; blocks 3C protease activity (IC50 = 0.36 mM); reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM); inhibits the growth of HCC cells in vitro and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model at 2 mg/kg; reduces acanthosis and expression of epidermal differentiation markers in a mouse model of imiquimod-induced psoriasis
Cayman Chemical EIcosapentaenoylLcarnItIn 50mg
A long-chain acylcarnitine; levels are increased in the eyes of mice fed a diet high in n-3/n-6 PUFAs, but not in mice fed normal diet, in a mouse model of myopia induced by out-of-focus lenses
Cayman Chemical trcetrapb 50mg
A CETP inhibitor (IC50s = 47 and 51 nM for cholesteryl and triglyceride transfer, respectively); selective for CETP over PLTP, LCAT, and hepatic and lipoprotein lipases at 10 µM; inhibits CETP activity and increases HDL cholesterol levels in serum from transgenic mice expressing human CETP and ApoA1 at 30 mg/kg; increases mean arterial blood pressure in Zucker fa/fa diabetic rats at 60 and 200 mg/kg
Cayman Chemical KetrolaccalcIum salt 100mg
An NSAID and COX inhibitor (IC50 = 20 nM for both COX-1 and COX-2); prevents increases in paw swelling, increases paw withdrawal latency in a hot-plate test, and decreases PGE2 levels in paw tissue in a mouse model of carrageenan-induced inflammation at 30 mg/kg; a racemic mixture of the active (S)-ketorolac and inactive (R)-ketorolac enantiomers
Cayman Chemical NalmefenhydrochlorIde 50mg
A μ- and κ-opioid receptor antagonist (Kis = 0.91 and 1.03 nM, respectively, in CHO membranes expressing the human receptors); selective for μ- and κ-opioid receptors over δ-opioid receptors (Ki = 13.26 nM in CHO membranes expressing the human receptors); decreases self-administration of alcohol in non-alcohol- and alcohol-dependent rats; reduces food and water intake and body weight in obese and lean rats at 25 mg/kg per day; inhibits morphine-induced scratching behavior and increases in the latency to tail withdrawal in a warm water tail withdrawal assay in rhesus monkeys at 32 UG/kg
Cayman Chemical 2 7DICLOrdIhydrofluorSceI 50mg
A fluorescent indicator of peroxynitrite formation; neither NO, superoxide, nor hydrogen peroxide alone appear to oxidize DCFH
Cayman Chemical 5trns Fluprostnl Isopropy 50mg
A potential impurity in commercial preparations of travoprost