Sera
Cayman Chemical Termitomycamide B, Purity: ≥97%, CAS: 1254277-89-8, 50 mg
A fatty acid amide from T. titanicus that at 0.1 μg/ml protects against ER stress-dependent cell death in Neuro2a cells induced by tunicamycin
Cayman Chemical INCB 3284 (dimesylate), Purity: ≥95%, CAS: 887401-93-6, 50 mg
A potent, selective, and orally bioavailable antagonist of MCP-1 binding to CCR2 (IC50 = 3.7 nM); inhibits chemotaxis in vitro (IC50 = 4.7 nM) and displays acceptable oral bioavailability in mice, rats, dogs, monkeys, and chimpanzees
Cayman Chemical Alexidine (hydrochloride), Purity: ≥98%, CAS: 1715-30-6, 50 mg
An alkyl bis(biguanide) antiseptic which kills plaque forming microorganisms; binds to LPS and LTA and inhibits fungal phospholipase B (IC50 ~ 250 nM); inhibits the mitochondrial phosphatase PTPMT1 (IC50 = 1.08 μM, in vitro) and induces apoptosis in cancer cell lines (ED50 = 1.8-2.6 μM)
Cayman Chemical Ganciclovir, Purity: ≥95%, CAS: 82410-32-0, 50 mg
An active metabolite of valganciclovir and an antiviral nucleoside derivative; reduces human, monkey, mouse, and guinea pig CMV replication in plaque reduction assays (EC50s = 1.3-70 µM); topical application decreases disease severity and corneal leukocyte infiltration in a cat model of ocular FHV-1 epithelial infection at 0.15%; prevents allograft histologic injury and NK and myeloid cell infiltration in a mouse model of murine CMV infection with renal transplantation at 15 mg/kg; induces tumor regression in a K-BALB murine sarcoma model using a mixed population of HSV TK positive or negative cells
Sigma Aldrich Fine Chemicals Biosciences fetal Bovine srum fetal B500ML
Animal serum is commonly used to supplement basal media formulations for the optimal growth of many cell types in vitro. fetal Bovine Serum (fBS) is the most common serum used to supplement cell culture media due to its high nutritional content. Although it is relatively low in protein fBS is effective in promoting and sustaining growth of vertebrate mammalian and insect cells. IgG is the most common immunoglobulin present in fBS. Elevated levels of IgG may cause problems within certain recombinant protein or monoclonal antibody purification processes. for applications where IgG may interfere or cause issues we have depleted IgG levels in this fetal bovine serum by sequential chromatography down to a level of 5 ug/mL while maintaining performance equivalent to regular fBS.
Cayman Chemical (R)-Tetrahydrofuran-2-yl-methylamine, Purity: ≥95%, CAS: 7202-43-9, 50 mg
A synthetic intermediate useful for pharmaceutical synthesis.
Cayman Chemical (–)-Sitagliptin (phosphate), Purity: ≥98%, CAS: 654671-78-0, 100 mg
A DPP-4 inhibitor (IC50 = 18 nM); selective for DPP-4 over DPP-8 (IC50 = 48 µM) as well as several other peptidases; improves glucose tolerance in insulin-resistant Zucker fatty and high-fat diet fed rats as well as ob/ob and high-fat diet fed mice; reduces hyperglycemia in mice fed a high-fat diet with streptozotocin-induced diabetes
Cayman Chemical Dorsomorphin, Purity: ≥98%, CAS: 866405-64-3, 50 mg
A potent, reversible inhibitor of AMPK (Ki = 109 nM); dose-dependently inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK6); downregulates the Akt/mTOR pathway to induce autophagy in U251 human glioma cells
Cayman Chemical Pimecrolimus, Purity: ≥98%, CAS: 137071-32-0, 100 mg
A macrolactam that binds to macrophilin-12 and inhibits calcineurin as well as prolyl isomerase; the activation of T cells by allogeneic dendritic cells (IC50 = 0.55 nM) and suppresses the generation of pro-inflammatory cytokines; used in countering inflammatory skin diseases, such as eczema and psoriasis
Cayman Chemical 1S 3S3Hydroxycyclopentn 50mg
A synthetic intermediate useful for pharmaceutical synthesis.
Sigma Aldrich Fine Chemicals Biosciences fetal Bovine srum Austral500ML
fetal Bovine srum Austral500ML
Sigma Aldrich Fine Chemicals Biosciences Bovine Calf Serum USA orig
Animal serum is commonly used to supplement basal media formulations for the optimal growth of many cell types in vitro. Bovine Calf Serum (BCS) is collected from calves that are less than 12 months old. The serum contains approximately double the protein of fetal bovine serum (fBS). BCS will promote growth in a variety of mammalian cell lines and is often used as a cost-effective substitute for fBS.
Cayman Chemical EnzalutamIde 50mg
A non-steroidal androgen receptor antagonist (IC50 = 36 nM); reduces the efficiency of nuclear translocation of the androgen receptor and impairs both its binding to DNA and the recruitment of coactivators