Cayman Chemical Isobavachalcon 50mg
A chalcone and flavonoid with diverse biological activities; active against C. albicans and C. neoformans (IC50s = 3 and 7 UG/ml, respectively), as well as T. rubrum and M. audouinii (MIC = 1.2 UG/ml for both); active against various bacteria (MICs = 4.9-39.1 UG/ml); induces mitochondrial-mediated apoptosis in IMR-32 and NB-39 human neuroblastoma cells; inhibits the proliferation of OVCAR-8 ovarian, PC3 prostate, MCF-7 breast, and A549 lung cancer cell lines; reduces dopaminergic neuronal cell death and increases the stay time in the rotarod test in a mouse model of MPTP-induced Parkinson’s disease at 50 mg/kg